Job Description P31677 Confidence 99.72% Date Thu Jan 5 11:48:33 GMT 2012 Rank 38 Aligned Residues 372 % Identity 14% Template c2iyfA_ PDB info PDB header:transferase Chain: A: PDB Molecule:oleandomycin glycosyltransferase; PDBTitle: the crystal structure of macrolide glycosyltransferases: a2 blueprint for antibiotic engineering Resolution 1.7 Å

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.			.	.	.	30	.	.	.	.	.	.	.		.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.
Predicted Secondary structure																											.	.												.
Query SS confidence																											.	.												.
Query Sequence		S	R	L	V	V	V	S	N	R	I	A	P	P	D	E	H	A	A	S	A	G	G	L	A	V	.	.	G	I	L	G	A	L	K	A	A	G	G	.	L	W	F	G	W	S	G	E	T	G	N	E	D	Q	P	L	K	K	V	K	K	G	N	I	T	W	A	S	F	N	L	S	E	Q	D	L	D	E	Y	Y	N
Query Conservation																											.	.												.
Alig confidence										.	.	.	.	.	.	.	.	.									.	.												.										.	.	.	.	.	.
Template Conservation										.	.	.	.	.	.	.	.	.																																.	.	.	.	.	.
Template Sequence		A	H	I	A	M	F	S	I	.	.	.	.	.	.	.	.	.	A	A	H	G	H	V	N	P	S	L	E	V	I	R	E	L	V	A	R	G	H	R	V	T	Y	A	I	P	P	V	F	.	.	.	.	.	.	A	D	K	V	A	A	T	G	P	R	P	V	L	Y	H	S	T	L	P	G	P	D	A	D	P	E
Template Known Secondary structure										.	.	.	.	.	.	.	.	.	S						G	G	G										T	T									G	G	G	.	.	.	.	.	.						T	T	S										S			T	T	S		G	G
Template Predicted Secondary structure										.	.	.	.	.	.	.	.	.																																.	.	.	.	.	.
Template SS confidence
		7	.	.	10	.	.	.	.										.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.							.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.
		79	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	F	S	N	A	V	L	W	P	A	F	H	Y	R	L	D	L	V	Q	F	Q	R	P	A	W	D	G	Y	L	R	V	N	A	L	L	A	D	K	L	L	P	L	L	Q	D	D	D	I	I	W	I	H	D	Y	H	L	L	P	F	A	H	E	L	R	K	R	G	V	N	N	R	I	G	F	F	L	H	I	P	F
Query Conservation
Alig confidence										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																													.
Template Conservation										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																													.
Template Sequence		A	W	G	S	T	L	L	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	V	E	P	F	L	N	D	A	I	Q	A	L	P	Q	L	A	D	A	Y	A	D	D	I	P	D	L	V	L	H	D	I	T	S	Y	P	A	R	V	L	A	R	R	W	.	G	V	P	A	V	S	L	S	P	N	L	V
Template Known Secondary structure		G	G		S	S				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																					T	T	S			S						T	T												.	T								S	S
Template Predicted Secondary structure										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																													.
Template SS confidence
		72	.	.	.	.	.	.	.																80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.		.	.	.	.	.	.	130	.	.	.	.	.
		159	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	T	P	E	I	F	N	A	L	P	T	Y	D	T	L	L	E	Q	L	C	D	Y	D	L	L	G	F	Q	T	E	N	D	R	L	A	F	L	D	C	L	S	N	L	T	R	V	T	T	R	S	A	K	S	H	T	A	W	G	K	A	F	R	T	E	V	Y	P	I	G	I	E	P	K	E	I	A	K	Q	A	A
Query Conservation
Alig confidence																					.	.	.	.	.	.	.	.	.
Template Conservation																					.	.	.	.	.	.	.	.	.
Template Sequence		A	W	K	G	Y	E	E	E	V	A	E	P	M	W	R	E	P	R	Q	.	.	.	.	.	.	.	.	.	T	E	R	G	R	A	Y	Y	A	R	F	E	A	W	L	K	E	N	G	I	T	E	H	P	D	T	F	A	S	H	P	P	R	S	L	V	L	I	P	K	A	L	Q	P	H	A	D	R	V	D	E	D
Template Known Secondary structure				T	T					T											.	.	.	.	.	.	.	.	.	S																	T	T			S										S	S					S		G	G	G	S	T	T	G	G	G	S		T	T
Template Predicted Secondary structure																					.	.	.	.	.	.	.	.	.
Template SS confidence
		136	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.										.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.			.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
Predicted Secondary structure																	.	.
Query SS confidence																	.	.
Query Sequence		G	P	L	P	P	K	L	A	Q	L	K	A	E	L	K	.	.	N	V	Q	N	I	F	S	V	E	R	L	D	Y	S	K	G	L	P	E	R	F	L	A	Y	E	A	L	L	E	K	Y	P	Q	H	H	G	K	I	R	Y	T	Q	I	A	P	T	S	R	G	D	V	Q	A	Y	Q	D	I	R	H	Q	L	E	N
Query Conservation																	.	.
Alig confidence																	.	.																																				.	.	.	.												.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																						.	.	.	.												.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		V	Y	T	F	V	G	A	C	Q	E	G	G	W	Q	R	P	A	G	A	E	K	V	V	L	V	S	L	G	S	A	F	T	Q	P	A	F	Y	R	E	C	V	R	A	F	G	N	L	P	G	W	H	L	.	.	.	.	V	L	Q	I	G	T	P	A	E	L	G	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		T																T	T		S								T	T	T															T	T		T	T				.	.	.	.							G	G	G	G		.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																						.	.	.	.												.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		207	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.					.	260	.	.	.	.	.	.	.	.	.
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.
Predicted Secondary structure																																																																																	.
Query SS confidence																																																																																	.
Query Sequence		E	A	G	R	I	N	G	K	Y	G	Q	L	G	W	T	P	L	Y	Y	L	N	Q	H	F	D	R	K	L	L	M	K	I	F	R	Y	S	D	V	G	L	V	T	P	L	R	D	G	M	N	L	V	A	K	E	Y	V	A	A	Q	D	P	A	N	P	G	V	L	V	L	S	Q	F	A	G	A	A	N	E	L	.
Query Conservation																																																																																	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.																.	.	.																	.	.	.	.												.																		.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.																.	.	.																	.	.	.	.												.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	E	L	P	D	N	V	E	V	H	D	W	V	P	Q	L	.	.	.	A	I	L	R	Q	A	D	L	F	V	T	H	A	G	A	G	.	.	.	.	G	S	Q	E	G	L	A	T	A	T	P	.	M	I	A	V	P	Q	A	V	D	Q	F	G	N	A	D	M	L	Q
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	S			T	T					S	S					.	.	.				T	T		S										.	.	.	.								T	T			.							S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.																.	.	.																	.	.	.	.												.
Template SS confidence
														279	280	.	.	.	.	.	.	.	.	.	290	.	.	.				.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.					310	.	.	.	.	.	.	.	.	.	320		.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.
				396	.	.	.	400	.	.	.	.	.			.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.
Predicted Secondary structure		.	.											.	.
Query SS confidence		.	.											.	.
Query Sequence		.	.	T	S	A	L	I	V	N	P	Y	D	.	.	R	D	E	V	A	A	A	L	D	R	A	L	T	M	S	L	A	E	R	I	S	R	H	A	E	M	L	D	V	I	V	K	N	D	I	N	H	W	Q	E	C	F	I	S	D	L
Query Conservation		.	.											.	.
Alig confidence		.	.											.	.														.
Template Conservation																													.
Template Sequence		G	L	G	V	A	R	K	L	A	T	E	E	A	T	A	D	L	L	R	E	T	A	L	A	L	V	D	.	D	P	E	V	A	R	R	L	R	R	I	Q	A	E	M	A	Q	E	G	G	T	R	R	A	A	D	L	I	E	A	E	L
Template Known Secondary structure			T	T	S								.																.																														T	T	S
Template Predicted Secondary structure																													.
Template SS confidence
		339	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.		.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.