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Job DescriptionP77538
Confidence99.52%DateThu Jan 5 12:30:21 GMT 2012
Rank208Aligned Residues186
% Identity10%Templatec2px6A_
PDB info PDB header:transferaseChain: A: PDB Molecule:thioesterase domain; PDBTitle: crystal structure of the thioesterase domain of human fatty2 acid synthase inhibited by orlistat
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   73......80.........90.........100.........110.........120.........130.........140.........150..
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Query Sequence  PADNAIATIIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVL
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Template Sequence  SVQSSERPLFLVHPIEGSTTVFHSLASRL. . . SIPTYGLQCTRAAPLD. . . . . . . . SIHSLAAYYIDCIRQVQPEGPYRV
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SS



TT

SGGG
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TTS
TT........
TTT
SS


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   2236...2240.........2250.........2260.... .....2270.........2280 .........2290.........2300....
 
   153......160......... 170.........180.........190.........200.........210......
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Query Sequence  FGQSIGGANILDVIGRG. . . DREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSP. . . . . . . . . . . . .
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Template Sequence  AGYSYGACVAFEMCSQLQAQQPTHNSLFLFDGSPTYAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAAVDLI
Template Known Secondary structure  T




S
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S


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S
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   2305....2310.........2320.........2330.........2340.........2350.........2360.........2370.........2380....
 
   217..220.........230.........240.........250.........260
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . IPLLLIHGKADHVIPWQHSEKLYSLAKEPKRLILIPDGEHIDAF
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Template Sequence  IKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGADYNLS. . . . . . QVCDGKVSVHVIEG. DHRTLL
Template Known Secondary structure 
TTS
T



S
B
S



TTTTTT......TTB
S
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TTGGG
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   2405....2410.........2420.........2430.........2440.........2450....... ..2460.........2470. ......
 
   261........270......
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Query Sequence  SDRHGDVYREQMVDFI
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Template Sequence  EGSGLESIISIIHSSL
Template Known Secondary structure  S
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   2486...2490.........2500.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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