Job Description P11447 Confidence 100.00% Date Thu Jan 5 11:32:38 GMT 2012 Rank 14 Aligned Residues 415 % Identity 17% Template c2vd6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:adenylosuccinate lyase; PDBTitle: human adenylosuccinate lyase in complex with its substrate2 n6-(1,2-dicarboxyethyl)-amp, and its products amp and3 fumarate. Resolution 2.00 Å

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		6	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.		50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.
Predicted Secondary structure																																														.
Query SS confidence																																														.
Query Sequence		G	R	F	T	Q	A	A	D	Q	R	F	K	Q	F	N	D	S	L	R	F	D	Y	R	L	A	E	Q	D	I	V	G	S	V	A	W	S	K	A	L	V	T	V	G	V	.	L	T	A	E	E	Q	A	Q	L	E	E	A	L	N	V	L	L	E	D	V	R	A	R	P	Q	Q	I	L	E	S	D	A	E	D	I
Query Conservation																																														.
Alig confidence						.	.											.	.	.	.	.																								.																												.	.	.
Template Conservation						.	.											.	.	.	.	.																																																				.	.	.
Template Sequence		S	R	Y	A	.	.	S	P	E	M	C	F	V	F	S	D	.	.	.	.	.	R	Y	K	F	R	T	W	R	Q	L	W	L	W	L	A	E	A	E	Q	T	L	G	L	P	I	T	D	E	Q	I	Q	E	M	K	S	N	L	E	N	I	D	F	K	M	A	A	E	E	E	K	R	.	.	.	L	R	H	D	V
Template Known Secondary structure			T	T	S	.	.								T	S		.	.	.	.	.																					T	T		S												T	S	S														.	.	.		S
Template Predicted Secondary structure						.	.											.	.	.	.	.																																																				.	.	.
Template SS confidence
		19	20	.	.			.	.	.	.	.	.	.	30	.	.						.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.				.	.	.	.	.
		85	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	S	W	V	E	G	K	L	I	D	K	V	G	Q	L	G	K	K	L	H	T	G	R	S	R	N	D	Q	V	A	T	D	L	K	L	W	C	K	D	T	V	S	E	L	L	T	A	N	R	Q	L	Q	S	A	L	V	E	T	A	Q	N	N	Q	D	A	V	M	P	G	Y	T	H	L	Q	R	A	Q	P	V	T
Query Conservation
Alig confidence		.
Template Conservation		.
Template Sequence		.	M	A	H	V	H	T	F	G	H	C	C	P	K	A	A	G	I	I	H	L	G	A	T	S	C	Y	V	G	D	N	T	D	L	I	I	L	R	N	A	L	D	L	L	L	P	K	L	A	R	V	I	S	R	L	A	D	F	A	K	E	R	A	S	L	P	T	L	G	F	T	H	F	Q	P	A	Q	L	T	T
Template Known Secondary structure		.												T	T	T	G	G	G	T	T	T	T			T																																					T	T	T								T	T
Template Predicted Secondary structure		.
Template SS confidence
			89	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
		165	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.					.	.	.	.	.	.	.	.								210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
Predicted Secondary structure																																							.	.	.	.									.	.	.	.	.	.	.
Query SS confidence																																							.	.	.	.									.	.	.	.	.	.	.
Query Sequence		F	A	H	W	C	L	A	Y	V	E	M	L	A	R	D	E	S	R	L	Q	D	A	L	K	R	L	D	V	S	P	L	G	C	G	A	L	A	.	.	.	.	G	T	A	Y	E	I	D	R	.	.	.	.	.	.	.	E	Q	L	A	G	W	L	G	F	A	S	A	T	R	N	S	L	D	S	V	S	D	R	D
Query Conservation																																							.	.	.	.									.	.	.	.	.	.	.
Alig confidence																																							.	.	.	.									.	.	.	.	.	.	.																	.
Template Conservation																																																																										.
Template Sequence		V	G	K	R	C	C	L	W	I	Q	D	L	C	M	D	L	Q	N	L	K	R	V	R	D	D	L	R	F	R	G	V	K	G	T	T	G	T	Q	A	S	F	L	Q	L	F	E	G	D	D	H	K	V	E	Q	L	D	K	M	V	T	E	K	A	G	F	K	R	A	F	I	I	T	.	G	Q	T	Y	T	R	K
Template Known Secondary structure																													B			S			T	T	S	S								T	T	T																T	T		S		B		S			.	S	S	S			T
Template Predicted Secondary structure																																																																										.
Template SS confidence
		168	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.		240	.	.	.	.	.	.
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310		.	.
Predicted Secondary structure																																																																															.
Query SS confidence																																																																															.
Query Sequence		H	V	L	E	L	L	S	A	A	A	I	G	M	V	H	L	S	R	F	A	E	D	L	I	F	F	N	T	G	E	A	G	F	V	E	L	S	D	R	V	T	S	G	S	S	L	M	P	Q	K	K	N	P	D	A	L	E	L	I	R	G	K	C	G	R	V	Q	G	A	L	T	G	M	M	M	T	L	.	K	G
Query Conservation																																																																															.
Alig confidence																													.	.								.	.	.	.	.	.	.	.	.	.																																.
Template Conservation																													.	.								.	.	.	.	.	.	.	.	.	.
Template Sequence		V	D	I	E	V	L	S	V	L	A	S	L	G	A	S	V	H	K	I	C	T	D	I	R	L	L	A	.	.	N	L	K	E	M	E	E	.	.	.	.	.	.	.	.	.	.	P	F	Y	K	R	N	P	M	R	S	E	R	C	C	S	L	A	R	H	L	M	T	L	V	M	D	P	L	Q	T	A	S	V	Q
Template Known Secondary structure																													.	.		T	T	S				.	.	.	.	.	.	.	.	.	.																								T									T
Template Predicted Secondary structure																													.	.								.	.	.	.	.	.	.	.	.	.
Template SS confidence
		247	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.			.	.	.	.	.	.	280											.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.
		313	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.			.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390
Predicted Secondary structure																																																			.	.
Query SS confidence																																																			.	.
Query Sequence		L	P	L	A	Y	N	K	D	M	Q	E	D	K	E	G	L	F	D	A	L	D	T	W	L	D	C	L	H	M	A	A	L	V	L	D	G	I	Q	V	K	R	P	R	C	Q	E	A	A	Q	.	.	Q	G	Y	A	N	A	T	E	L	A	D	Y	L	V	A	K	G	V	P	F	R	E	A	H	H	I	V	G	E
Query Conservation																																																			.	.
Alig confidence																																																			.	.
Template Conservation
Template Sequence		W	F	E	R	T	L	D	D	S	A	N	R	R	I	C	L	A	E	A	F	L	T	A	D	T	I	L	N	T	L	Q	N	I	S	E	G	L	V	V	Y	P	K	V	I	E	R	R	I	R	Q	E	L	P	F	M	A	T	E	N	I	I	M	A	M	V	K	A	G	G	S	R	Q	D	C	H	E	K	I	R	V
Template Known Secondary structure			T	T			G	G	G																											S	S																															T	T
Template Predicted Secondary structure
Template SS confidence
		326	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.
		391	.	.	.	.					.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.
Predicted Secondary structure							.	.	.	.
Query SS confidence							.	.	.	.
Query Sequence		A	V	V	E	A	.	.	.	.	I	R	Q	G	K	P	L	E	D	L	P	L	S	E	L	Q	K	F	S	Q	V	I	D	E	D	V	Y	P	I	L	S	L	Q	S	C	L	D	K	R	A	A	K	G	G	V	S	P	Q	Q	V	A	Q	A	I	A	F
Query Conservation							.	.	.	.
Alig confidence							.	.	.	.																																					.	.	.	.	.	.	.
Template Conservation																																															.	.	.	.	.	.	.
Template Sequence		L	S	Q	Q	A	A	S	V	V	K	Q	E	G	G	D	N	D	L	I	E	R	I	Q	V	D	A	Y	F	S	P	I	H	S	Q	L	D	H	L	L	D	P	S	S	F	T	.	.	.	.	.	.	.	G	R	A	S	Q	Q	V	Q	R	F	L	E	E
Template Known Secondary structure													S														G	G	G	G	G	G	G	G	G					T		G	G	G	G	S	.	.	.	.	.	.	.	T	T
Template Predicted Secondary structure																																															.	.	.	.	.	.	.
Template SS confidence
		406	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450								.	.	.	.	.	.	.	.	.	460	.	.	.