|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | |
. | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 60 | |
|
|
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
T | K | P | I | V | F | S | G | A | Q | P | S | G | E | . |
L | T | I | G | N | Y | M | G | A | L | R | Q | W | V | N | M | Q | D | D | Y | H | C | I | Y | C | I | V | D | Q | H | A | I | T | V | R | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | A | Q | K | L | R | K | A | T | . |
. |
. |
L | D | T | L | A | L | Y |
Query Conservation |   |
  |
|   |   |
|   |
|
|   |   |
|
|
|   | . |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |
|   |   |
|
|
|   |   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
E | R | V | T | L | Y | C | G | F | D | P | T | A | D | S | L | H | I | G | H | L | A | T | I | L | T | M | R | R | F | Q | Q | A | G | H | R | P | I | A | L | V | G | G | A | T | G | L | I | G | D | P | S | G | K | K | S | E | R | T | L | N | A | K | E | T | V | E | A | W | S | A | R | I | K | E | Q | L | G | R | F |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  |
|
| S | S | S | S |
| B | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
| T | T | G | G | G | T |
|
|
| T | T |
| S | S |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
29 | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . |
  |
  |   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
|
140 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
Query Sequence |   |
L | A | C | G | I | D | P | E | K | S | T | I | F | V | Q | S | H | V | P | E | H | A | Q | L | G | W | A | L | N | C | Y | T | Y | F | G | E | L | S | R | M | T | Q | F | K | D | K | S | A | R | Y | A | E | N | I | N | A | G | L | F | D | Y | P | V | L | M | A | A | D | I | L | L | Y | . |
. |
. |
. |
Q | T | N | L |
Query Conservation |   |
  |
|   |
|   |
|
|   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|   |   | . | . | . | . |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
Template Conservation |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|
Template Sequence |   |
L | D | F | E | A | D | G | N | P | A | K | I | K | N | N | Y | D | W | I | G | P | L | D | V | I | T | F | L | R | D | V | G | K | H | F | S | V | N | Y | M | M | A | K | E | S | V | Q | S | R | I | E | T | G | I | S | F | T | E | F | S | Y | M | M | L | Q | A | Y | D | F | L | R | L | Y | E | T | E | G | C | R | L |
Template Known Secondary structure |   |
S |
| S | S |
| S | S | S |
|
|  |  |  |  | T |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  | T | G | G | G |
|
|  |  |  |  |  | T | S |  |  |  |  | T | T | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
109 | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . |
  |
  |   |
144 | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | P | V | G | E | D | Q | K | Q | H | L | E | L | S | R | D | I | A | Q | R | F | N | A | L | Y | G | E | I | F | K | V | P | E | P | F | I | P | K | S | G | A | R | V | M | S | L | L | E | P | T | K | K | M | S | K | S | D | D | N | R | N | N | V | I | G | L | L | E | D | P | K | S | V | V | K | K | I | K | R | A |
Query Conservation |   |
|
|   |
|   |
|
|   |   |
|
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |
|   |
|   |
|   |
|   |
|
|   |
|   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|
|   |   |   |
|   |   |   |
|
|
|
|   |
|   |   | . | . | . | . | . | . | . |   |
|
|   |   |
| . | . | . |   |   |
|
|
|   |
|
| . | . |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |
|   |   |
|
|   |   |   |
Template Sequence |   |
Q | I | G | G | S | D | Q | W | G | N | I | T | A | G | L | E | L | I | R | K | T | K | . |
. |
. |
. |
. |
. |
. |
G | R | A | F | G | L | . |
. |
. |
T | I | P | L | V | T | K | A | . |
. |
D | G | T | K | F | G | K | T | E | S | G | T | I | W | L | D | K | E | K | T | S | P | Y | E | F | Y | Q | F | W | I | N | T |
Template Known Secondary structure |   |
 |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|  |  |  | . | . | . |  |  |
|
|
|
|
| T | . | . | T | S |
|
| T | T |
|
| S | S |
|
|
| B | S | S | T | T | T | S |
|  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . |
|
|
|  |  |  | . | . | . |  |  |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
189 | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
|
|
|
|
|
|
. | . | . | . | . | . | |
|
|
. | . | . | 220 | . | . | . | . | |
|
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . |
  |
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | |
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | T | D | S | D | E | P | P | V | V | R | Y | D | V | Q | N | K | A | G | V | S | N | L | L | D | I | L | S | A | V | T | G | Q | S | I | P | E | L | E | K | Q | F | . |
E | G | K | M | Y | G | H | L | K | G | E | V | A | D | A | V | S | G | M | L | T | E | L | Q | E | R | Y | H | R | F | R |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   | . |   |   |
|   |   |   |
|
|
|   |   |
|
|
|   |
|   |   |   |
|   |
|   |
|
|
|   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | D | R | D | V | I | R | Y | L | K | Y | F | T | F | L | S | K | E | E | I | E | A | L | E | Q | E | L | R | E | A | P | E | K | R | A | A | Q | K | T | L | A | E | E | V | T | K | L | V | H | G | E | E | A | L | R | Q | A | I | R |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
  |