|   |
2 | . | . | . | . | . | . | . | 10 | . | . | |
. | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
|
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | K | P | I | V | F | S | G | A | Q | P | . |
S | G | E | L | T | I | G | N | Y | M | G | A | L | R | Q | W | V | N | M | Q | D | . |
D | Y | H | C | I | Y | C | I | V | D | Q | H | A | I | T | V | R | Q | . |
. |
D | A | Q | K | L | R | K | A | T | L | D | T | L | A | L | Y | L | A | C | G | I | D | P | E | K | S |
Query Conservation |   |
  |
|   |   |
|   |
|
|   |   |
| . |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   | . |
|   |   |   |   |   |   |
|
|
|   |
|
|   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|
|
|
|   |   |
|
|
|
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |
|   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
Template Sequence |   |
H | P | I | Y | I | Y | T | G | R | G | P | S | S | G | A | L | H | L | G | H | L | L | P | F | I | F | T | K | Y | L | Q | D | A | F | K | C | Y | V | V | I | Q | I | T | D | D | E | K | F | L | R | N | R | S | L | S | Y | A | E | V | D | S | Y | T | R | E | N | I | K | D | I | I | A | C | G | F | D | P | D | K | T |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
| S | S |
|
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| G | G | G |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
T | I | F | V | Q | S | H | V | P | E | H | A | Q | L | G | W | A | L | N | C | Y | T | Y | F | G | E | L | S | R | M | T | Q | F | K | D | K | S | A | R | Y | A | E | N | I | N | A | G | L | F | D | Y | P | V | L | M | A | A | D | I | L | L | Y | Q | T | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | I | F | I | N | S | Q | Y | L | S | L | K | N | R | Y | R | F | S | C | L | V | D | R | M | L | P | I | S | Q | L | R | A | S | . |
. |
. |
. |
F | G | F | S | N | D | A | N | V | G | Y | A | A | F | P | P | K | Q | M | L | P | V | Y | S | T | Y | F | D | G | L | P | F | T | R | V | P | L | P | V | G | A | V | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T | S | T | T |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  | . | . | . | . |  |
|
|
| S | S |
|
|  |  |  |  | T |
|  |  |  |  |  | G | G | G | S | G | G | G | G | T | T | S | G | G | G |
| S | B |
|
|
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . | . | . | . |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | |
|
|
|
. | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | V | P | V | G | E | D | Q | K | Q | H | L | E | L | S | R | D | I | A | Q | R | F | N | A | L | Y | G | E | I | F | K | V | P | E | P | F | I | P | K | S | G | A | R | V | M | S | L | L | E | P | T | K | K | M | S | K | S | D | D |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|   |
|   |
|
|   |   |
|
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|
|
|
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|   |   |
|
|   |
|   |
|
|
|
|   |
|   |   | . | . | . | . | . | . |   |   |   |
|   |   |
| . | . | . |   |   |   |   |
|
|
|
|   |
|   |   |   |
|
|
|
|
|   |   |
Template Sequence |   |
S | P | V | H | V | V | E | E | L | F | P | D | S | K | R | Y | Q | K | A | M | C | L | I | A | S | G | I | E | Q | D | P | Y | F | R | L | A | R | D | L | A | P | R | M | G | . |
. |
. |
. |
. |
. |
H | P | K | N | A | Y | L | . |
. |
. |
L | G | K | F | L | P | G | L | Q | G | S | G | T | K | M | S | A | S | D | P |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |
| G | G | G | T | T | B |
|
|
|  |  |  |  |  |  |
| T | T | T |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T | . | . | . | . | . | . | S |
|
|
|  |  |  | . | . | . |  |  |
|
|
|
|
| T | T |
| T | T |
|
|
|
| S | S |
| G |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|  |  |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
|
|
|
|
. | . | . | . | . | . | . | |
|
|
. | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
  |
  |   |
202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | |
|
270 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | R | N | N | V | I | G | L | L | E | D | P | K | S | V | V | K | K | I | K | R | A | V | T | D | S | D | E | P | P | V | V | R | Y | D | V | Q | N | K | A | G | V | S | N | L | L | D | I | L | S | A | V | T | G | Q | S | I | P | E | L | E | K | Q | F | E | G | K | M | . |
. |
Y | G | H | L | K | G | E | V | A | D |
Query Conservation |   |
|   |   |
|   |
|   |
|   |
|   |
|
|   |
|   |   |
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   | . | . |   |   |
|
|
|   |   |
|
|
|
Alig confidence |   |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . |
|
|
|   |
|   |
|   |
|
|   |
|   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   | . |
|   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |
|
|   |
|
|   |
|
|
|
Template Sequence |   |
N | . |
. |
S | A | I | Y | L | T | D | T | P | A | Q | I | K | N | K | I | N | R | Y | A | F | S | G | G | R | D | T | A | F | G | . |
A | D | L | S | V | D | V | S | V | R | Y | L | E | V | F | M | K | . |
D | D | A | E | L | E | K | L | K | A | D | Y | K | T | G | K | L | L | T | G | E | V | K | A | T | L | I | G |
Template Known Secondary structure |   |
G | . | . | G | S |
| B | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| S |
|
|
|
|
|
| . |
|
| T | T | T |
|  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
| . | . |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
318 | |
|
. | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | |
. | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | |
. | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . |
  |
  |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | V | S | G | M | L | T | E | L | Q | E | R | Y | H | R | F | R | N | D |
Query Conservation |   |
  |
|   |   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |
|   |
Template Sequence |   |
I | L | Q | G | L | I | K | E | H | A | E | R | R | D | K | V | D | T | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
399 | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . |
  |