|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
S | D | Y | Q | M | F | E | V | Q | V | S | Q | V | E | P | L | T | . |
. |
. |
. |
. |
E | Q | V | K | R | F | T | L | V | A | T | D | G | K | P | L | P | A | F | T | G | G | S | H | V | I | V | Q | M | S | D | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
| . | . | . | . | . |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   | . |   |
|   |   |
|
|   |
|   |
|   |
|   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
H | K | K | R | V | S | A | A | R | L | L | S | R | Q | N | L | Q | S | P | K | S | S | R | S | T | I | F | V | R | L | H | T | N | G | N | Q | E | L | . |
Q | Y | Q | P | G | D | H | L | G | V | F | P | G | N | H | E | D | L | V | N | A | L | I | E | R | L | E | D | A | P | P | A | N | H | V | V | K | V | E | M | L |
Template Known Secondary structure |   |
T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |
| S |
| T | T |
| S | S |
|  |  |  |  |  |  |  |
| T | T |
| G | G | G | . |
|
|
| T | T |
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  | T | T |
| S | S |
|
|
| S |
| S |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
988 | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | |
. | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
Template Sequence |   |
E | E | R | N | T | A | L | G | V | I | S | N | W | K | D | E | S | R | L | P | P | C | T | I | F | Q | A | F | K | Y | Y | L | D | I | T | T | P | P | T | P | L | Q | L | Q | Q | F | A | S | L | A | T | N | E | K | E | K | Q | R | L | L | V | L | S | K | G | L | Q | E | Y | E | E | W | K | W | G | K | N | P | T | M |
Template Known Secondary structure |   |
 |  |
|
|
| S | S | S |
|
|  |  |  |  |  |
|
| S | S |
| S | B |
|  |  |  |  |  |  |  | T | B |
|
| S | S |
|
|
|  |  |  |  |  |  |  |  | T | T | B |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  |  |  |  |  |
|
|
|  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1067 | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
51 | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | |
. | . | . | 70 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | N | Q | Y | S | N | A | Y | S | L | L | S | S | P | H | D | . |
T | S | C | Y | Q | I | A | V | R | L | E | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | S | R | G | G | S | R | F | L | H | Q | Q | V | K | V | G | D | R | L | T |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |
|   |
|
|
|
|
|   |
|   |   | . |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |
|
|
|   |   |   |
|
|   |   |
|
|   |   |
|
|   |
|   |
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   | . |   |
|   |   |
|
|   |
|   |
Template Sequence |   |
V | E | V | L | E | E | F | P | S | I | Q | M | P | A | T | L | L | L | T | Q | L | S | L | L | Q | P | R | Y | Y | S | I | S | S | S | P | D | M | Y | P | D | E | V | H | L | T | V | A | I | V | S | Y | H | T | R | D | G | E | G | P | V | H | H | G | V | C | S | S | W | L | N | . |
R | I | Q | A | D | D | V | V | P |
Template Known Secondary structure |   |
 |  |  |  |  |  | S | T | T | B |
|
|
|  |  |  |  |  |  |  | S |
| B |
|
|
|  |  |  |  | B |
| S |
| T | T | T | S | T | T |  |  |  |  |  |  |  |
|
|  |  |  | T | G | G | G | T | S |
|  |  |  |
|  |  |  |  |  |  | T | . | T |
|
| T | T | S |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|  |  |  | . |
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1147 | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | |
. | . | . | 1220 | . | . | . | . | . |
  |
  |   |
99 | 100 | . | . | . | . | . | . | . | . | . | 110 | . | |
|
. | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | |
. | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
|
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  | . |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
| . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
I | S | T | P | N | N | L | F | A | L | I | P | S | . |
. |
A | R | K | H | L | F | I | A | G | G | I | G | I | T | P | F | L | S | H | M | A | E | L | Q | . |
. |
. |
. |
. |
. |
. |
H | S | D | V | D | W | Q | L | H | Y | C | S | R | N | P | E | . |
S | C | A | F | R | D | E | L | V | Q | H | P | Q | A | E | . |
. |
Query Conservation |   |
  |   |   |
|   |
|   |
|   |   |   |   |   | . | . |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |
|   |   |
|   | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   | . |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
C | F | V | R | G | A | P | S | F | H | L | P | R | N | P | Q | V | P | C | I | L | V | G | P | G | T | G | I | A | P | F | R | S | F | W | Q | Q | R | Q | F | D | I | Q | H | K | G | M | N | P | C | P | M | V | L | V | F | G | C | R | Q | S | K | I | D | H | I | Y | R | E | E | T | L | Q | A | K | N | K | G | V | F |
Template Known Secondary structure |   |
 |  |  |  |
|
| G | G | G | S |
|
| S |
| T | T | S |
|  |  |  |  |  |  | G | G | G | G | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
|
|  |  |  |  |  |  |  | S |
| T | T | T | T |
| T | T |  |  |  |  |  |  |  |  |  | T | T | S |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1226 | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260 | . | . | . | . | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | . | . | . | . |
  |
  |   |
|
167 | . | . | 170 | . | . | . | . | |
|
. | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . |
Predicted Secondary structure |   |
. |
|  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
K | V | H | L | H | H | S | S | . |
. |
T | G | T | R | L | E | L | A | R | L | L | A | D | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | P | G | T | H | V | Y | T | C | G | P | E | A | L | I | E | A | V | R | S | E | A | A | R |
Query Conservation |   |
. |   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |   |   |   |   |
|
|   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|
|   |   |   |   |   |
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
R | E | L | Y | T | A | Y | S | R | E | P | D | R | P | K | K | Y | V | Q | D | V | L | Q | E | Q | L | A | E | S | V | Y | R | A | L | K | E | Q | G | G | H | I | Y | V | C | G | D | V | T | M | A | A | D | V | L | K | A | I | Q | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | S | S |
| T | T | S |
|
|
|
|  |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1306 | . | . | . | 1310 | . | . | . | . | . | . | . | . | . | 1320 | . | . | . | . | . | . | . | . | . | 1330 | . | . | . | . | . | . | . | . | . | 1340 | . | . | . | . | . | . | . | . | . | 1350 | . | . | . | . | . | . | . | . | . | 1360 | . | . | . | . |
  |