|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | |
|
. | . | . | . | |
|
|
|
|
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
. | . | . | . | . | . | . | |
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  | . | . |  |  |  |
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | M | R | A | V | D | A | A | M | Y | V | L | E | K | E | G | I | T | T | . |
. |
A | F | G | V | . |
. |
. |
. |
. |
P | G | A | A | I | N | P | F | Y | S | A | M | R | K | H | G | . |
G | I | R | H | I | L | A | . |
R | H | V | E | G | A | S | H | M | A | E | G | Y | T | R | A | T | A | G | N | I | G | V | C | L |
Query Conservation |   |
  |
|   |
|
|
|   |
|   |   |   |
|   |   |   |
|
|   |   | . | . |
|
|
|   | . | . | . | . | . |
|
|   |   |   |   |   |
|   |   |
|
|   |   |   |   | . |   |
|   |   |
|   |   | . |   |   |
|   |   |
|
|   |   |
|   |
|
|
|
|   |
|   |
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |
|
|
|
|
|   |   |
|
|   |
|
|
|
|
|   | . |   | . |
|   |   |
|
|
|   |
Template Sequence |   |
Q | V | T | V | R | D | A | I | N | Q | G | X | D | E | E | L | E | R | D | E | K | V | F | L | L | G | E | E | V | A | Q | Y | D | G | A | Y | K | V | S | R | G | L | W | K | K | Y | G | D | K | R | I | I | D | T | P | I | S | E | X | G | F | A | G | I | A | V | G | A | A | X | . |
A | . |
G | L | R | P | I | C | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  |  | T | T |
| S | T | T |
|
| T | T | S | T | T | T | T |  |  |  |  |  |
| T | T | T |  |  |  |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | T | . | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
| . |
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | |
. | |
. | . | . | . | . | . | . |
  |
  |   |
74 | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
. | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | T | S | G | P | A | G | T | D | M | I | T | A | L | Y | S | A | S | A | . |
. |
. |
. |
. |
. |
. |
D | S | I | P | I | L | C | I | T | G | Q | A | P | R | A | R | L | H | K | E | D | F | Q | A | V | D | I | E | A | I | A | K | P | V | . |
S | K | M | A | V | T | V | R | E | A | A | L | V | P | R | V | L | Q | Q |
Query Conservation |   |
  |
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |
|   |   | . | . | . | . | . | . | . |   |   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   | . |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|
|
|
|   |
|   |   |
|
|
|   |   |
|   |   |   |   |
|   |   |
Template Sequence |   |
F | X | T | F | N | F | S | X | Q | A | I | D | Q | V | I | N | S | A | A | K | T | Y | Y | X | S | G | G | L | Q | P | V | P | I | V | F | R | G | P | N | G | A | S | A | G | V | A | A | Q | H | S | Q | C | F | A | A | W | Y | G | H | C | P | G | L | K | V | V | S | P | W | N | S | E | D | A | K | G | L | I | K | S |
Template Known Secondary structure |   |
| S | S | G | G | G | G | G | G | T |  |  |  |  |  |  | T | T | T | T |  |  |  |  | T | T | S | S |
|
|
|
|
|  |  |  |  |  |
| S |
|
| S | S |
|
| G | G | G |
|
|
|
|  |  |  |  |  | T | S | T | T |
|  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | F | H | L | M | R | S | G | R | P | G | P | V | L | V | D | L | P | F | D | V | Q | V | A | E | I | E | F | D | P | D | M | Y | E | P | L | P | V | Y | K | P | A | A | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | M | Q | I | E | K | A | V | E | M | L | I | Q | A | E | R | P | V | I |
Query Conservation |   |
|   |   |   |
|   |   |   |   |   |
|
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|
Alig confidence |   |
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   | . | . | . | . | . |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|
|
|
|
|   |
|   |   |
|   |   |
|
|   |
|
|   |   |
|   |   |   |
|
|   |   |   |
Template Sequence |   |
A | I | R | . |
. |
. |
. |
. |
D | N | N | P | V | V | V | L | E | N | E | L | X | Y | G | V | P | F | E | F | P | P | E | A | Q | S | K | D | F | L | I | P | I | G | K | A | K | I | E | R | Q | G | T | H | I | T | V | V | S | H | S | R | P | V | G | H | C | L | E | A | A | A | V | L | S | K | E | G | V | E | C | E |
Template Known Secondary structure |   |
 |  |  | . | . | . | . | . | S | S | S |
|  |  |  |  |  |
| T | T | T | T | T |
|  |  |  |  |
|  |  |  |  | S | T | T |
|
|
|
| T | T |
|
|  |  |  |  |
|
| S | S |  |  |  |  |  |
| S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
  |
  |   |
209 | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | A | G | G | G | V | I | N | A | D | A | A | A | L | L | Q | Q | F | A | E | L | T | S | V | P | V | I | P | T | L | M | G | W | G | C | I | P | D | D | H | E | L | M | A | G | M | V | G | L | Q | T | A | H | R | Y | G | N | A | T | L | L | A |
Query Conservation |   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|   |   |   |   |
|
| . | . | . | . | . |   |
|   |   |
|   |   |   |
|   |
|   |
Template Sequence |   |
V | I | N | X | R | T | I | R | P | X | D | X | E | T | I | E | A | S | V | X | K | T | N | H | L | V | T | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
E | G | G | W | P | Q | F | G | . |
. |
. |
. |
. |
V | G | A | E | I | C | A | R | I | X | E | G |
Template Known Secondary structure |   |
 |  |  |
|
|  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  | . | . | . | . | . | . | . | . | . |
| S | S |
| S | T | T | S | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 270 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 280 | . | . |
  |