Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	Q	A	A	L	N	T	R	N	S	E	E	E	V	S	S	R	R	N	N	G	T	R	L	A	G	I	L	F	L	L	T	V	L	T	T	V	L	V	S	G	W	V	V	L	G	W	M	E	D	A	Q	R	L	P	L	S	K	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																														?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	L	T	G	E	R	H	Y	T	R	N	D	D	I	R	Q	S	I	L	A	L	G	E	P	G	T	F	M	T	Q	D	V	N	I	I	Q	T	Q	I	E	Q	R	L	P	W	I	K	Q	V	S	V	R	K	Q	W	P	D	E	L	K
Secondary structure
SS confidence
Disorder											?										?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	H	L	V	E	Y	V	P	I	A	R	W	N	D	Q	H	M	V	D	A	E	G	N	T	F	S	V	P	P	E	R	T	S	K	Q	V	L	P	M	L	Y	G	P	E	G	S	A	N	E	V	L	Q	G	Y	R	E	M	G	Q	M
Secondary structure
SS confidence
Disorder																														?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	A	K	D	R	F	T	L	K	E	A	A	M	T	A	R	R	S	W	Q	L	T	L	N	N	D	I	K	L	N	L	G	R	G	D	T	M	K	R	L	A	R	F	V	E	L	Y	P	V	L	Q	Q	Q	A	Q	T	D	G	K	R
Secondary structure
SS confidence
Disorder			?	?	?	?																																																	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.
Sequence		I	S	Y	V	D	L	R	Y	D	S	G	A	A	V	G	W	A	P	L	P	P	E	E	S	T	Q	Q	Q	N	Q	A	Q	A	E	Q	Q
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2vh1 chain A Region: 58 - 260 Aligned: 203 Modelled: 203 Confidence: 100.0% Identity: 100% PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsq; PDBTitle: crystal structure of bacterial cell division protein ftsq2 from e.coli Phyre2 PDB 2vh2 chain A Region: 56 - 260 Aligned: 200 Modelled: 205 Confidence: 100.0% Identity: 72% PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsq; PDBTitle: crystal structure of cell divison protein ftsq from2 yersinia enterecolitica Phyre2 PDB 3j00 chain Z Region: 22 - 116 Aligned: 94 Modelled: 94 Confidence: 99.8% Identity: 89% PDB header:ribosome/ribosomal protein Chain: Z: PDB Molecule:cell division protein ftsq; PDBTitle: structure of the ribosome-secye complex in the membrane environment Phyre2 PDB 2alj chain A Region: 124 - 221 Aligned: 97 Modelled: 98 Confidence: 98.6% Identity: 12% PDB header:cell cycle Chain: A: PDB Molecule:cell-division initiation protein; PDBTitle: structure of the cis confomer of the major extracytoplasmic2 domain of the bacterial cell division protein divib from3 geobacillus stearothermophilus Phyre2 PDB 2qcz chain A Region: 55 - 132 Aligned: 74 Modelled: 78 Confidence: 94.0% Identity: 14% PDB header:membrane protein, protein transport Chain: A: PDB Molecule:outer membrane protein assembly factor yaet; PDBTitle: structure of n-terminal domain of e. coli yaet Phyre2 PDB 3efc chain A Region: 55 - 132 Aligned: 74 Modelled: 78 Confidence: 92.6% Identity: 14% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane protein assembly factor yaet; PDBTitle: crystal structure of yaet periplasmic domain Phyre2 PDB 2x8x chain X Region: 53 - 128 Aligned: 73 Modelled: 76 Confidence: 79.3% Identity: 12% PDB header:chaperone Chain: X: PDB Molecule:tlr1789 protein; PDBTitle: structure of the n-terminal domain of omp85 from the2 thermophilic cyanobacterium thermosynechococcus elongatus Phyre2 PDB 2v9h chain A Region: 52 - 132 Aligned: 77 Modelled: 81 Confidence: 61.4% Identity: 14% PDB header:protein-binding Chain: A: PDB Molecule:outer membrane protein assembly factor yaet; PDBTitle: solution structure of an escherichia coli yaet tandem potra2 domain Phyre2 PDB 3og5 chain A Region: 49 - 126 Aligned: 75 Modelled: 78 Confidence: 52.2% Identity: 16% PDB header:protein binding Chain: A: PDB Molecule:outer membrane protein assembly complex, yaet protein; PDBTitle: crystal structure of bama potra45 tandem Phyre2 PDB 3f41 chain B Region: 227 - 259 Aligned: 33 Modelled: 33 Confidence: 39.2% Identity: 27% PDB header:hydrolase Chain: B: PDB Molecule:phytase; PDBTitle: structure of the tandemly repeated protein tyrosine2 phosphatase like phytase from mitsuokella multacida Phyre2 PDB 2qdz chain A Region: 53 - 101 Aligned: 47 Modelled: 49 Confidence: 20.4% Identity: 4% PDB header:protein transport Chain: A: PDB Molecule:tpsb transporter fhac; PDBTitle: structure of the membrane protein fhac: a member of the2 omp85/tpsb transporter family Phyre2 PDB 2cw5 chain B Region: 115 - 138 Aligned: 24 Modelled: 24 Confidence: 13.4% Identity: 17% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:bacterial fluorinating enzyme homolog; PDBTitle: crystal structure of a conserved hypothetical protein from2 thermus thermophilus hb8 Phyre2 PDB 3mc8 chain A Region: 51 - 206 Aligned: 153 Modelled: 156 Confidence: 12.7% Identity: 11% PDB header:membrane protein Chain: A: PDB Molecule:alr2269 protein; PDBTitle: potra1-3 of the periplasmic domain of omp85 from anabaena Phyre2 PDB 1q1v chain A Region: 70 - 104 Aligned: 35 Modelled: 35 Confidence: 12.5% Identity: 11% Fold: Another 3-helical bundle Superfamily: DEK C-terminal domain Family: DEK C-terminal domain Phyre2 PDB 3lno chain A Region: 92 - 115 Aligned: 24 Modelled: 24 Confidence: 10.6% Identity: 17% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of domain of unknown function duf59 from2 bacillus anthracis Phyre2 PDB 3jru chain B Region: 125 - 220 Aligned: 88 Modelled: 96 Confidence: 8.5% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:probable cytosol aminopeptidase; PDBTitle: crystal structure of leucyl aminopeptidase (pepa) from xoo0834,2 xanthomonas oryzae pv. oryzae kacc10331 Phyre2 PDB 1gyt chain A domain 2 Region: 125 - 220 Aligned: 88 Modelled: 96 Confidence: 7.6% Identity: 15% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: Leucine aminopeptidase, C-terminal domain Phyre2 PDB 3m92 chain B Region: 122 - 142 Aligned: 21 Modelled: 21 Confidence: 6.6% Identity: 10% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein ycin; PDBTitle: the structure of ycin, an unchracterized protein from shigella2 flexneri. Phyre2 PDB 1uwd chain A Region: 92 - 115 Aligned: 23 Modelled: 24 Confidence: 5.4% Identity: 13% Fold: Alpha-lytic protease prodomain-like Superfamily: Fe-S cluster assembly (FSCA) domain-like Family: PaaD-like Phyre2 1 c2vh1A_ 2 c2vh2A_ 3 c3j00Z_ 4 c2aljA_ 5 c2qczA_ 6 c3efcA_ 7 c2x8xX_ 8 c2v9hA_ 9 c3og5A_ 10 c3f41B_ 11 c2qdzA_ 12 c2cw5B_ 13 c3mc8A_ 14 d1q1va_ 15 c3lnoA_ 16 c3jruB_ 17 d1gyta2 18 c3m92B_ 19 d1uwda_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2vh1A_ 100.0 100 PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsq; PDBTitle: crystal structure of bacterial cell division protein ftsq2 from e.coli 2 c2vh2A_ 100.0 72 PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsq; PDBTitle: crystal structure of cell divison protein ftsq from2 yersinia enterecolitica 3 c3j00Z_ 99.8 89 PDB header:ribosome/ribosomal protein Chain: Z: PDB Molecule:cell division protein ftsq; PDBTitle: structure of the ribosome-secye complex in the membrane environment 4 c2aljA_ 98.6 12 PDB header:cell cycle Chain: A: PDB Molecule:cell-division initiation protein; PDBTitle: structure of the cis confomer of the major extracytoplasmic2 domain of the bacterial cell division protein divib from3 geobacillus stearothermophilus 5 c2qczA_ 94.0 14 PDB header:membrane protein, protein transport Chain: A: PDB Molecule:outer membrane protein assembly factor yaet; PDBTitle: structure of n-terminal domain of e. coli yaet 6 c3efcA_ 92.6 14 PDB header:membrane protein Chain: A: PDB Molecule:outer membrane protein assembly factor yaet; PDBTitle: crystal structure of yaet periplasmic domain 7 c2x8xX_ 79.3 12 PDB header:chaperone Chain: X: PDB Molecule:tlr1789 protein; PDBTitle: structure of the n-terminal domain of omp85 from the2 thermophilic cyanobacterium thermosynechococcus elongatus 8 c2v9hA_ 61.4 14 PDB header:protein-binding Chain: A: PDB Molecule:outer membrane protein assembly factor yaet; PDBTitle: solution structure of an escherichia coli yaet tandem potra2 domain 9 c3og5A_ 52.2 16 PDB header:protein binding Chain: A: PDB Molecule:outer membrane protein assembly complex, yaet protein; PDBTitle: crystal structure of bama potra45 tandem 10 c3f41B_ 39.2 27 PDB header:hydrolase Chain: B: PDB Molecule:phytase; PDBTitle: structure of the tandemly repeated protein tyrosine2 phosphatase like phytase from mitsuokella multacida 11 c2qdzA_ 20.4 4 PDB header:protein transport Chain: A: PDB Molecule:tpsb transporter fhac; PDBTitle: structure of the membrane protein fhac: a member of the2 omp85/tpsb transporter family 12 c2cw5B_ 13.4 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:bacterial fluorinating enzyme homolog; PDBTitle: crystal structure of a conserved hypothetical protein from2 thermus thermophilus hb8 13 c3mc8A_ 12.7 11 PDB header:membrane protein Chain: A: PDB Molecule:alr2269 protein; PDBTitle: potra1-3 of the periplasmic domain of omp85 from anabaena 14 d1q1va_ 12.5 11 Fold:Another 3-helical bundle Superfamily:DEK C-terminal domain Family:DEK C-terminal domain 15 c3lnoA_ 10.6 17 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of domain of unknown function duf59 from2 bacillus anthracis 16 c3jruB_ 8.5 11 PDB header:hydrolase Chain: B: PDB Molecule:probable cytosol aminopeptidase; PDBTitle: crystal structure of leucyl aminopeptidase (pepa) from xoo0834,2 xanthomonas oryzae pv. oryzae kacc10331 17 d1gyta2 7.6 15 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Leucine aminopeptidase, C-terminal domain 18 c3m92B_ 6.6 10 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein ycin; PDBTitle: the structure of ycin, an unchracterized protein from shigella2 flexneri. 19 d1uwda_ 5.4 13 Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:PaaD-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0