|   |
409 | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | |
. | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | |
|
|
. | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | Y | A | A | N | Y | R | S | E | H | L | W | I | V | A | R | . |
D | G | V | E | V | P | V | S | L | V | Y | H | R | K | H | F | R | K | G | H | N | P | L | L | V | Y | G | Y | G | S | Y | G | A | S | I | D | A | D | F | S | F | S | . |
. |
. |
R | L | S | L | L | D | R | G | F | V | Y | A | I | V | H | V | R | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   | . | . | . |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |
| . | . | . | . | . |   |   |   |   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
Template Sequence |   |
F | S | R | P | G | L | P | V | E | Y | L | Q | V | P | S | P | S | M | G | R | D | I | K | V | Q | F | Q | S | G | . |
. |
. |
. |
. |
G | A | N | S | P | A | L | Y | L | L | D | G | L | R | A | Q | D | D | F | S | G | W | D | I | N | T | P | A | F | E | W | Y | D | Q | S | G | L | S | V | V | M | P | V | G | G | Q |
Template Known Secondary structure |   |
B | S | S | T | T |
|
|
|  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | S | T | T | B |
|  |  |  |  |  |
|
| T | T |
|
| S | S | S |
|  |  |  |  |  |
|
|  |  |  |  |  | T | T | S | S |
|  |  |  |  |  |
|
|
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . |
  |
  |   |
485 | . | . | . | . | 490 | . | . | . | . | . | |
. | . | . | . | 500 | . | . | . | . | . | . | . | . | . | |
|
510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | G | E | L | G | Q | Q | W | Y | E | D | . |
G | K | F | L | K | K | K | N | T | F | N | D | Y | L | . |
. |
D | A | C | D | A | L | L | K | L | G | Y | G | S | P | S | L | C | Y | A | M | G | G | S | A | G | G | M | L | M | G | V | A | I | N | Q | R | P | E | L | F | H | G | V | I | A | Q | V | P | F | V | D | V |
Query Conservation |   |
|   |
|   |
|   |   |
|   |   |
| . |   |   |   |   |   |   |   |   |   |   |   |
|   |
| . | . |
|   |   |   |   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |
|   |   |   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |
Template Sequence |   |
S | S | F | Y | S | D | W | Y | Q | P | A | C | G | K | A | G | C | Q | T | Y | K | W | E | T | F | L | T | S | E | L | P | G | W | L | Q | A | N | R | H | V | K | P | T | G | S | A | V | V | G | L | S | M | A | A | S | S | A | L | T | L | A | I | Y | H | P | Q | Q | F | V | Y | A | G | A | M | S | G | L | L | D | P |
Template Known Secondary structure |   |
T |
| T | T |
| B |
| S | S |
|  |  |  | T | T |  |  |  |
|
| B |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |
| B |
| S | S | S |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | T |  |  |  |  |  |  |  | S |
|
| S |
| T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
  |
  |   |
562 | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | |
|
|
. | . | . | . | . | . | 610 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |
|  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
Query Sequence |   |
V | T | T | M | L | D | E | S | I | P | L | T | T | G | E | F | E | E | W | G | N | P | Q | D | P | Q | Y | Y | . |
. |
. |
. |
. |
. |
E | Y | M | K | S | Y | S | P | Y | D | N | V | T | A | . |
. |
. |
Q | A | Y | P | H | L | L | V | T | T | G | L | H | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|
|   |   |   |
|   |   | . | . | . |   |   |   |
|   |   |
|
|   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | Q | A | M | G | P | T | . |
. |
. |
. |
L | I | G | L | A | M | G | D | A | G | G | Y | K | A | S | D | M | W | G | P | K | E | D | P | A | W | Q | R | N | D | P | L | L | N | V | G | K | L | I | A | N | N | T | R | . |
V | W | V | Y | C | G | N | G | K | P | S | D | L | G | G | N | N | L | P | A | K | F | L | E |
Template Known Secondary structure |   |
T | S | T | T |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  | T | T | S |
|
|  |  |  |  |  |
| S | T | T | S | T |  |  |  |  | S |
| T | T | T | T |  |  |  |  |  |  |  | T |
|  | . |  |  |  |  |
|
|
| S |
|
| B | T | T | B |
|
| S |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
156 | . | . | . | 160 | . | . | |
|
|
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 |
  |
  |   |
619 | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | V | Q | Y | W | E | P | A | K | W | V | A | K | L | R | E | L | K | T | D | D | H | L | L | L | L | C | T | D | M | D | S | G | H | G | G | K | S | G | R | F | K | S | Y | E | G | V | A | M | E | Y | A | F | L | V | A | L | A | Q | G | T | L |
Query Conservation |   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |
|   | . | . | . | . |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
Template Sequence |   |
G | F | V | R | T | S | N | I | K | F | Q | D | A | Y | N | A | G | G | G | H | N | . |
. |
G | V | F | D | F | P | D | S | G | T | H | S | . |
. |
. |
. |
W | E | Y | W | G | A | Q | L | N | A | M | K | P | D | L | Q | R | A | L | G | A | T | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S | . | . |  |  |  |  |
|
| S |
|
|
| S | S | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  | T |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  | . | . |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
231 | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | |
|
. | . | . | . | . | . | . | . | 260 | . | . | . | |
|
|
|
. | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . |
  |