|   |
414 | . | . | . | . | . | 420 | . | . | . | . | . | . | |
|
. | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | |
|
|
|
. | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
| . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
Y | R | S | E | H | L | W | I | V | A | R | D | G | . |
. |
V | E | V | P | V | S | L | V | Y | H | R | K | H | F | R | K | G | H | N | P | L | L | V | Y | G | Y | G | S | Y | G | A | S | I | D | A | D | F | S | F | . |
. |
. |
. |
S | R | L | S | L | L | D | R | G | F | V | Y | A | I | V | H | V | R | G | G | G | . |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|
| . | . |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |
|   |   | . | . | . | . |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |
|
|
|   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |
|   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|   |
|   |   |   |
|   |
|
|   |
|   |
Template Sequence |   |
Y | P | A | E | E | Y | E | V | V | T | E | D | G | Y | I | L | G | I | D | R | I | P | Y | G | R | K | N | S | E | N | I | G | R | R | P | V | A | F | L | Q | H | G | L | L | A | S | A | T | N | W | I | S | N | L | P | N | N | S | L | A | F | I | L | A | D | A | G | Y | D | V | W | L | G | N | S | R | G | N | T | W |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |  |  |  |
| S |
| S | S |
|
| T | T | T | T | T |
|
|  |  |  |  |  |
|
| T | T |
|
| G | G | G | G | S | S | S |
| T | T | T |
|  |  |  |  |  |  |  | T | T |
|  |  |  |  |
|
|
| T | T | S | T | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . |
  |
  |   |
|
|
|
|
|
487 | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | |
|
|
. | 550 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
E | L | G | Q | Q | W | Y | E | D | G | K | F | L | K | K | K | N | T | F | N | D | Y | L | D | A | C | D | A | L | L | K | L | G | Y | G | S | P | S | L | C | Y | A | M | G | G | S | A | G | G | M | L | M | G | V | A | I | N | Q | R | P | E | L | . |
. |
. |
F | H | G | V | I | A | Q | V | P | F |
Query Conservation |   |
. | . | . | . | . |
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
| . | . | . |
|   |
|   |
|   |   |   |
|
|
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |
|   |   | . | . |
|
|   |
|
|
|
|
|   |
|
|   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
A | R | R | N | L | Y | Y | S | P | D | S | V | E | F | W | A | F | S | F | D | E | M | A | K | Y | D | L | P | A | T | I | D | F | I | L | K | K | T | G | Q | D | . |
. |
K | L | H | Y | V | G | H | S | Q | G | T | T | I | G | F | I | A | F | S | T | N | P | K | L | A | K | R | I | K | T | F | Y | A | L | A | P | V |
Template Known Secondary structure |   |
S |
|  |  | S | S | S |
| T | T | S | T | T | T | T |
|
|
|  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | . | . |
|  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  | T | T |  |  |  |  |  |  |  | S |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | |
|
. | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . |
  |
  |   |
559 | 560 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 570 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | D | V | V | T | T | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | D | E | S | I | P | L | T | T | G | E | F | E | E |
Query Conservation |   |
  |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | T | V | K | Y | T | E | T | L | I | N | K | L | M | L | V | P | S | F | L | F | K | L | I | F | G | N | K | I | F | Y | P | H | H | F | F | D | Q | F | L | A | T | E | V | C | S | R | E | T | V | D | L | L | C | S | N | A | L | F | I | I | C | G | F | D | T | M | N | L | N | M | S | R | L | D | V | Y | L | S | H |
Template Known Secondary structure |   |
S |
|
| S | S |
|
| S | G | G | G | G | G | G | T | S |
|  |  |  |  |  |  |  | S |
| S | S |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  | T | T | T | B | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| G | G | G | S |
| G | G | G |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
183 | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
  |
  |   |
580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | G | N | P | Q | D | P | Q | Y | Y | E | Y | M | K | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | S | P | Y | D | N | V | T | A | Q | A | Y | P | H | L | L | V | T | T | G | L | H | D | S | Q | V | Q | Y | W | E | P | A | K | W | V | A | K | L | R | E |
Query Conservation |   |
  |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
| . |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | P | A | G | T | S | V | Q | N | V | L | H | W | S | Q | A | V | K | S | G | K | F | Q | A | F | D | W | G | S | P | V | Q | N | M | M | H | Y | H | Q | S | M | P | P | Y | Y | N | L | T | D | M | H | V | P | . |
I | A | V | W | N | G | G | N | D | L | L | A | D | P | H | D | V | D | L | L | L | S | K | L | P | N |
Template Known Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |
| B |
|
|
|
| S | S |  |  |  |  |  |  |  |  | S | S | S | S |
|
| B |
|
| G | G | G |
|
| S |
| . |  |  |  |  |  |  | T | T |
| S | S | S |
|  |  |  |  |  |  |  |  | T | T |
| T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . |  |  |  |  |  |  |
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
263 | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | |
. | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
  |
  |   |
635 | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | |
|
|
. | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | T | D | D | H | L | L | L | L | C | T | D | M | D | S | G | H | G | . |
. |
. |
G | K | S | G | R | F | K | S | Y | E | G | V | A | M | E | Y | A | F | L |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
| . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
Alig confidence |   |
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
| . | . |   |   |   |
|   |   |
|
|
Template Sequence |   |
L | . |
. |
. |
. |
. |
. |
I | Y | H | R | K | I | P | P | Y | N | H | L | D | F | I | W | A | M | D | A | P | Q | A | V | . |
. |
Y | N | E | I | V | S | M | M |
Template Known Secondary structure |   |
 | . | . | . | . | . | . |  |  |  |  |  |  | T | T |
|
| T | T |  |  |  |  |
| T | T |  |  |  |  | T | . | . |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
| . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
342 | |
|
|
|
|
|
. | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | |
|
. | . | . | 370 | . | . | . | . |
  |