|   |
415 | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | |
. | . | 470 | . | . | . | |
. | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . |  |  |  |  |  |
| . |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | S | E | H | L | W | I | V | A | R | D | G | V | E | V | P | V | S | L | V | Y | H | R | K | H | F | R | K | G | H | N | P | L | L | V | Y | G | Y | G | S | Y | G | A | S | I | D | A | D | F | S | F | S | R | . |
L | S | L | L | D | R | . |
G | F | V | Y | A | I | V | H | V | R | G | G | G | E | L | G | Q | Q | W |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   | . |   |   |
|   |   |   | . |
|   |   |
|   |   |   |
|   |
|
|
|   |
|   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
| . |   |   |   |   |   |
|   |   |
| . | . | . | . | . |   |   |   |   |
|
|
|
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
Template Sequence |   |
R | V | E | D | R | T | I | K | G | R | N | G | . |
D | I | R | V | R | V | Y | Q | Q | . |
. |
. |
. |
. |
K | P | D | S | P | V | L | V | Y | Y | H | G | G | G | F | V | I | C | S | I | E | S | H | D | A | L | C | R | R | I | A | R | L | S | N | S | T | V | V | S | V | D | Y | R | L | A | P | E | H | K | F | P | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |  | . |  |  |  |  |  |  |  |  | S | . | . | . | . | . | S | S | S |  |  |  |  |  |  |  |
|
| S | T | T | T | S |
|
| T | G | G | G |  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |  |  |  |  |
|
|
| T | T | T | S |
| T | T |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
| . |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
55 | . | . | . | . | 60 | . | . | . | . | . | . | |
. | . | . | 70 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . |
  |
  |   |
493 | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | |
|
|
520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | |
|
|
|
. | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
Y | E | D | G | K | F | L | K | K | K | N | T | F | N | D | Y | L | D | A | C | D | A | L | L | K | L | G | . |
. |
. |
Y | G | S | P | S | L | C | Y | A | M | G | G | S | A | G | G | M | L | M | G | V | A | I | N | Q | R | P | E | . |
. |
. |
. |
L | F | H | G | V | I | A | Q | V | P | F | V | D | V | V | T | T | . |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |
|
|   |   |
| . | . | . |   |   |
|   |   |
|
|   |
|   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
| . | . | . | . |
|
|   |
|   |
|   |   |   |
|
|   |
|   |   |   |   | . |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
A | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | D | C | Y | D | A | T | K | W | V | A | E | N | A | E | E | L | R | I | D | P | S | K | I | F | V | G | G | D | S | A | G | G | N | L | A | A | A | V | S | I | M | A | R | D | S | G | E | D | F | I | K | H | Q | I | L | I | Y | P | V | V | N | F | V | A | P | T |
Template Known Secondary structure |   |
 |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  | S |
|
|
|
| S | S | S |
|
|
Template Predicted Secondary structure |   |
|  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
129 | 130 | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
565 | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | |
. | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
M | L | D | E | S | I | P | L | T | T | G | E | F | E | E | W | G | N | P | . |
Q | D | P | Q | Y | Y | E | Y | M | K | S | Y | S | P | Y | D | N | V | T | A | Q | A | Y | P | H | L | L | V | T | T | G | L | H | D | S | Q | V | Q | Y | W | E | P | A | K | W | V | A | K | L | R | E | L | K | T | D |
Query Conservation |   |
. | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
| . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
| . |   |
|
|   |   |
|   |   |
|   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
Template Sequence |   |
P | S | L | L | E | F | G | E | G | L | W | I | L | D | Q | K | I | M | S | W | F | S | E | Q | Y | F | S | R | E | E | D | K | F | N | P | L | A | S | V | I | F | A | D | L | E | N | L | P | P | . |
A | L | I | I | T | A | E | Y | D | P | L | R | D | . |
. |
E | G | E | V | F | G | Q | M | L | R | R | A | G | V | E |
Template Known Secondary structure |   |
 |  |  |  |  | T | S | S | S |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |
| S | S | G | G | G | G | G |
| T | T | T | S | G | G | G | S |
|
| T | T |
|
|
| . |  |  |  |  |  |  |  |  |
| T | T |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . |  |  |  |  |  |
|
|
|
|
|
|  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
198 | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | |
. | . | . | 250 | . | . | . | . | . | . | . | . | . | |
|
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . |
  |
  |   |
639 | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | |
|
|
. | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | H | L | L | L | L | C | T | D | M | D | S | G | H | G | . |
. |
. |
G | K | S | G | R | F | K | S | Y | E | G | V | A | M | E | Y | A | F | L | V |
Query Conservation |   |
  |   |   |
|   |
|   |   |   |   |   |   |
|
|
| . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |
|   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |
Template Sequence |   |
. |
. |
. |
A | S | I | V | R | Y | R | G | V | L | H | G | F | I | N | Y | Y | P | V | L | K | A | A | R | D | A | I | N | Q | I | A | A | L | L | V |
Template Known Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  | T | T | G | G | G | G | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
275 | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
  |