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Job DescriptionP24555
Confidence100.00%DateThu Jan 5 11:41:42 GMT 2012
Rank4Aligned Residues659
% Identity23%Templatec3iumA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:prolyl endopeptidase; PDBTitle: appep_wtx opened state
Resolution2.25 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.........70.........80.
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Query Sequence  LPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQENSYGHRVMASQQALQDRILKEIIDRIPQREVSAPYIKN
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Template Conservation   
            
    
 
 

 
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Template Sequence  YPVTRQGEQVDHYFGQAVADPYRWLED. . DRSPETEAWVKAQNAVTQDYLAQIP. YRAAIKEKLAASWNYAKEGAPFREG
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TT

S

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T.TS





T
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   910.........20.........30..... ....40.........50.........60 .........70.........80.....
 
   82.......90.........100.........110.........120.........130.........140.........150.........160.
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Query Sequence  GYRYRHIYEPGCEYAIYQRQSAFSEEWDEWETLLDANKRAAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNLE
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Template Sequence  RYHYFFKNDGLQNQNVLWRQ. . . . QEGKPAEVFLDPNTLSPD. GTTALDQLSFSRDGRILAYSLSLAGSDWREIHLXDVE
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SS
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   86...90.........100..... ....110.........120... ......130.........140.........150.........160
 
   162.......170.........180.........190.........200.........210.........220 .........230.........
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Query Sequence  TGNWYPELLDNVEPSFVWANDSWIFYYVRKHPVTLLPYQVWRHAIGTPASQDKLIYEEK. . DDTYYVSLHKTTSKHYVVI
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Template Conservation 

                
  
    
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Template Sequence  SKQPLETPLKDVKFSGISWLGNEGFFYSSYDKP. TDQHKVYFHRLGTAQEDDRLVFGAIPAQHHRYVGATVTEDDRFLLI
Template Known Secondary structure  TTS


TTTSS

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TTS
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   161........170.........180.........190... ......200.........210.........220.........230.........
 
   240.........250.........260.........270.........280.........290.........300.........310........
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Query Sequence  . HLASATTSEVRLLDAEMADAEPFVFLPRRKDHEYSLDHYQHRFYLRSNRHGKNFGLYRTRMRDEQQWEELIPPRENIML
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Template Conservation                                                 
        
                       
Template Sequence  SAANSTSGNRLYVKDLSQENAPLLTVQGDLDADVSLVDNKGSTLYLLTNRDAPNRRLVTVDAANPGPAHWRDLIPERQQV
Template Known Secondary structure  SSSS

TTSTT



SSSS
TT
TT
TT
TTS

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   248.250.........260.........270.........280.........290.........300.........310.........320.......
 
   319320.........330.........340.........350.........360.........370.........380.........390........
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Query Sequence  EGFTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAYVTWIAYNPEPETARLRYGYSSMTTPDTLFELDMDTGER
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Template Conservation           
           
   
        
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Template Sequence  LTVHSGSGYLFAEYXVDATARVEQFDYEGKRVREVALPGLG. . SVSGFNGKHDDPALYFGFENYAQPPTLYRFEPKSGAI
Template Known Secondary structure 
TTTT
TTS



SSSS..



TT
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TTT

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   328.330.........340.........350.........360........ .370.........380.........390.........400.....
 
   399400.........410.........420.........430.........440.........450.........460.........470........
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Query Sequence  RVLKQTEVPGFYAANYRSEHLWIVARDGVEVPVSLVYHRKHFRKGHNPLLVYGYGSYGASIDADFSFSRLSLLDRGFVYA
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Template Conservation          .               
 

  

  
  
         
 

  



       
      
   
  
 
Template Sequence  SLYRASAA. PFKPEDYVSEQRFYQSKDGTRVPLIISYRKGLKLDGSNPTILYGYGGFDVSLTPSFSVSVANWLDLGGVYA
Template Known Secondary structure 


S.S

GGG
TTS
TT


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BTTB






TT
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   406...410... ......420.........430.........440.........450.........460.........470.........480....
 
   479480.........490.........500.........510.........520.........530.........540.........550........
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Query Sequence  IVHVRGGGELGQQWYEDGKFLKKKNTFNDYLDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPF
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Template Sequence  VANLRGGGEYGQAWHLAGTQQNKQNVFDDFIAAAEYLKAEGYTRTDRLAIRGGSNGGLLVGAVXTQRPDLXRVALPAVGV
Template Known Secondary structure 

TTSSSS
TTSGGGTTS

GGGT
TTT
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   485....490.........500.........510.........520.........530.........540.........550.........560....
 
   559560.........570.........580... ......590.........600..... ....610.........620.........630......
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Query Sequence  VDVVTTMLDESIPLTTGEFEEWGNP. QDPQYYEYMKSYSPYDNVTAQA. YPHLLVTTGLHDSQVQYWEPAKWVAKLRELK
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Template Conservation   
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Template Sequence  LDXLRY. . . HTFTAGTGWAYDYGTSADSEAXFDYLKGYSPLHNVRPGVSYPSTXVTTADHDDRVVPAHSFKFAATLQADN
Template Known Secondary structure 

GGGS...TTSGGGGG


SSS

TTTT

TT



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   565....570 .........580.........590.........600.........610.........620.........630.........640.
 
   637..640.........650.........660.........670.........680...
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Query Sequence  TDDHLLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGTLPAT
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Template Sequence  AGPHPQLIRIETPVAKL. . . . . . . . IEQSADIYAFTLYEXGYRELPR
Template Known Secondary structure 
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   642.......650........ .660.........670.........680
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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