|   |
418 | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | |
. | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | L | W | I | V | A | R | D | G | V | E | V | P | V | S | L | V | Y | H | R | K | H | F | R | K | G | H | N | P | L | L | V | Y | G | Y | G | S | Y | . |
G | A | S | I | D | A | D | F | S | F | S | R | L | S | L | L | D | R | G | F | V | Y | A | I | V | H | V | R | G | G | G | E | L | G | Q | Q | W | Y | E | D | G |
Query Conservation |   |
  |   |   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|
| . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |
|
|
|   |
|   |
|   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   | . | . |
Template Sequence |   |
K | Y | K | V | I | T | K | D | A | F | A | L | P | Y | T | I | I | K | A | K | N | . |
. |
. |
Q | P | T | K | G | V | I | V | Y | I | H | G | G | G | L | M | F | G | K | A | N | D | L | S | P | Q | Y | I | D | I | L | T | E | H | Y | D | L | I | Q | L | S | Y | R | L | L | P | E | V | S | L | D | C | I | I | . |
. |
Template Known Secondary structure |   |
 |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |
|
| S | S | . | . | . | S | S |
| S |  |  |  |  |  |  |
|
| S | T | T | T | S |
|
| T | T |
| S |
|  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |
|
|
|
| T | T | T | S |
|  |  |  |  |  | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
|
|
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | |
|
  |
  |   |
497 | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | F | L | K | K | K | N | T | F | N | D | Y | L | D | A | C | D | A | L | L | K | L | G | Y | G | S | P | S | L | C | Y | A | M | G | G | S | A | G | G | M | L | M | G | V | A | I | N | Q | R | P | E | L | F | H | G | V | I | A | Q | V | P | F | V | D | V | V | T | T | M | L | D | E | S | I | P | L | T | T | G | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | D | V | Y | A | S | F | D | A | I | Q | S | . |
. |
Q | Y | S | N | C | P | I | F | T | F | G | R | S | S | G | A | Y | L | S | L | L | I | A | R | D | R | D | I | D | G | V | I | D | F | Y | G | Y | S | R | I | N | T | E | P | F | K | T | . |
. |
. |
. |
. |
. |
T | N | S | Y |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | . | . | T | T | T | T | S |
|  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
| S |  |  |  |  |  | S |
|
| S |
| S |
| S |  |  |  |  | S | . | . | . | . | . | . |
|
|  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
80 | . | . | . | . | . | . | . | . | . | 90 | . | |
|
. | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 140 | . | . |
  |
  |   |
577 | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | E | E | W | G | N | P | Q | D | P | Q | Y | Y | E | Y | M | K | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | S | P | Y | D | N | V | T | A | Q | A | Y | P | H | L | L | V | T | T | G | L | H | D | S |
Query Conservation |   |
  |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . |   |
|
|
|   |
|   |   |
|   |
Template Sequence |   |
Y | A | K | I | A | Q | S | I | N | E | T | M | I | A | Q | L | T | S | P | T | P | V | V | Q | D | Q | I | A | Q | R | F | L | I | Y | V | Y | A | R | G | T | G | K | W | I | N | M | I | N | I | A | D | Y | T | D | S | K | Y | N | I | A | P | D | E | L | K | T | L | P | P | . |
V | F | I | A | H | C | N | G | D | Y |
Template Known Secondary structure |   |
 |  |  |  |  | T | T | S |
|  |  |  |  |  | T | T | S |
| S | S |
|
| S | S |
| S | S | G | G | G |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
|
| S |
| T | T | S | G | G | G | S |
|
|  |  |  |  | T | T |
|
|
| . |  |  |  |  |  |  | T | T |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . |
  |
  |   |
619 | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | |
. | . | . | . | 670 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | V | Q | Y | W | E | P | A | K | W | V | A | K | L | R | E | L | K | T | D | D | H | L | L | L | L | C | T | D | M | D | S | G | H | G | G | K | S | G | R | F | K | S | Y | E | G | V | . |
A | M | E | Y | A | F | L | V | A | L |
Query Conservation |   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   | . |
|   |   |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
Template Sequence |   |
D | V | P | V | E | E | S | . |
. |
. |
. |
E | H | I | M | N | H | V | P | H | S | T | F | E | R | V | . |
. |
. |
N | K | N | E | H | D | F | D | R | R | P | N | D | E | A | I | T | I | Y | R | K | V | V | D | F | L | N | A | I |
Template Known Secondary structure |   |
S | S |
| T |  |  |  | . | . | . | . |  |  |  |  | T | T |
| S | S |  |  |  |  |  |  | . | . | . |
| S | S |
| S |
| T | T | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  | . | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
222 | . | . | . | . | . | . | |
|
|
|
. | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
|
. | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
  |