Return to main results Retrieve Phyre Job Id

Job DescriptionP24555
Confidence100.00%DateThu Jan 5 11:41:42 GMT 2012
Rank9Aligned Residues532
% Identity15%Templatec2qtbB_
PDB info PDB header:hydrolaseChain: B: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor
Resolution2.25 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   129130.........140.........150.........160.........170.... .....180........
Predicted Secondary structure 


















....................




Query SS confidence 













































. . . . . . . . . . . . . . . . . . . .













Query Sequence  MGGMAITPDNTIMALAEDFLSRRQYGIRFRNLETGNWYPELLDNVE. . . . . . . . . . . . . . . . . . . . PSFVWANDSWIFYY
Query Conservation        




 

   
  
 
   
 
 

 

           ....................    

 

  
 
Alig confidence 



















......



















....................













Template Conservation       





 



 
  ......
 
     
    

  
    
          
          




  

 
Template Sequence  TQWVTWSPVGHKLAYVWNND. . . . . . IYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAY
Template Known Secondary structure  B

SSTT
TT......SSTTS



S

BTTTSB

TTSSSB

TTSS
Template Predicted Secondary structure 







......


























Template SS confidence 















































































   152.......160.........170. ........180.........190.........200.........210.........220.....
 
   189190......... 200.........210......... 220.........230
Predicted Secondary structure 







..............................








........



Query SS confidence 










. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .



















. . . . . . . .










Query Sequence  VRKHPVTLLPY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . QVWRHAIGTPASQDKLIYEE. . . . . . . . KDDTYYVSLHK
Query Conservation             .............................. 
    

       

   ........           
Alig confidence 










..............................



















........










Template Conservation     
   
                      
   
  
    
 
 
                                
Template Sequence  AQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTW
Template Known Secondary structure 
TT



STT
SS


BTTS


GGGTTTSSS






TS
Template Predicted Secondary structure 














































Template SS confidence 















































































   226...230.........240.........250.........260.........270.........280.........290.........300.....
 
   231........240.. .......250.........260..... ....270.........280.........290......
Predicted Secondary structure 





.












.............














Query SS confidence 











.






















. . . . . . . . . . . . .






























Query Sequence  TTSKHYVVIHLA. SATTSEVRLLDAEMADAEPFVFL. . . . . . . . . . . . . PRRKDHEYSLDHYQHRFYLRSNRHGKNFGLY
Query Conservation 
 

  
 
   .        
              .............                
   
        
 
Alig confidence 











.






















.............






























Template Conservation 
 

   
    
                                                
        
         
Template Sequence  ATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHIC
Template Known Secondary structure  TTSSTTTTTT
GGG

SSS
SSSSS




TTSS
TTS
Template Predicted Secondary structure 















































Template SS confidence 















































































   306...310.........320.........330.........340.........350.........360.........370.........380.....
 
   297..300.........310.........320.........330..... ....340.........350....... ..360.........370
Predicted Secondary structure 













....







..





Query SS confidence 






































. . . .





















. .












Query Sequence  RTRMRDEQQWEELIPPRENIMLEGFTLFTDWLVVEERQR. . . . GLTSLRQINRKTREVIGIAFDD. . PAYVTWIAYNPEP
Query Conservation                       
         

      ....
   
                 ..             
Alig confidence 










..

























....





















..












Template Conservation             ..

     
                          
  
          
              
 

Template Sequence  YFQIDKKDCTF. . ITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSK
Template Known Secondary structure  TT
S

..S

SSS

SSS
GGG
TT
BTTSSTTTSTTTB
B
T
Template Predicted Secondary structure 





..

































Template SS confidence 















































































   386...390...... ...400.........410.........420.........430.........440.........450.........460...
 
   371........380.........390.........400.........410..... ....420.........430.........440........
Predicted Secondary structure 

























..















Query SS confidence 












































. .
































Query Sequence  ETARLRYGYSSMTTPDTLFELDMDTGERRVLKQTEVPGFYAANYR. . SEHLWIVARDGVEVPVSLVYHRKHFRKGHNPLL
Query Conservation           

   
      
        
              ..       
 

  

  
  
         
 
Alig confidence 












































..
































Template Conservation 

   
   
    
               
                         

  
   
  
         
 
Template Sequence  EAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLL
Template Known Secondary structure  TSS
SBSS
TTTT

TT

TT
TT

TTS
Template Predicted Secondary structure 








































Template SS confidence 















































































   464.....470.........480.........490.........500.........510.........520.........530.........540...
 
   449450.........460. ........470.........480.........490.........500.........510.........520.....
Predicted Secondary structure 









...























Query SS confidence 












. . .































































Query Sequence  VYGYGSYGASIDA. . . DFSFSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKKNTFNDYLDACDALLKLGYGSPSL
Query Conservation 
  



      ... 
      
   
  
   
 


 
 
  
  
           
 

    

  
  
  
Alig confidence 












...































































Template Conservation      

                      
  
     

    
                 
              
   
Template Sequence  LDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKR
Template Known Secondary structure 


TT









STT



TT
SSS
GGGTT
TTSTTSS
Template Predicted Secondary structure 


































Template SS confidence 















































































   544.....550.........560.........570.........580.........590.........600.........610.........620...
 
   526...530.........540.........550.........560.........570.........580.........590.........600.....
Predicted Secondary structure 





























Query SS confidence 















































































Query Sequence  CYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVDVVTTMLDESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNVTAQA
Query Conservation 
 
 
 
 

 
        



 
 
   

 
                  
 
 
            

   
    
Alig confidence 






































.......

































Template Conservation 
 
 
 
 

             
 
 
      
    .......                        

        
Template Sequence  IAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYY. . . . . . . DSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK
Template Known Secondary structure  TTTT
S

SS



GGGS.......B

SSTTTTS
SGGGGGGGG
Template Predicted Secondary structure 










.......












Template SS confidence 















































































   624.....630.........640.........650.........660.. .......670.........680.........690......
 
   606...610.........620.........630.........640.........650.........660.........670.........
Predicted Secondary structure 



























Query SS confidence 









































































Query Sequence  YPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDDHLLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGT
Query Conservation   
  

  
  
 

      
    
         
 
      


            
    

       
Alig confidence 
































...














.





















Template Conservation    
 
   
  
  
           
   
  ...          
    .             
    
   
Template Sequence  QVEYLLIHGTADDNVHFQQSAQISKALVDVGVD. . . FQAMWYTDEDHGIAS. STAHQHIYTHMSHFIKQCFSLP
Template Known Secondary structure  GSTT
SSS
TTT

...
TT

TT

S.TT

Template Predicted Secondary structure 














...








.





Template SS confidence 









































































   697..700.........710.........720......... 730.........740.... .....750.........760......
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions