|   |
401 | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | Q | T | E | V | P | G | F | Y | A | A | N | Y | R | S | E | H | L | W | I | V | A | R | D | G | V | E | V | P | V | S | L | V | Y | H | R | K | H | F | R | K | G | H | N | P | L | L | V | Y | G | Y | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | Y | G | A | S | I | D | A | D | F | S | F | S | R | L | S | L |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
| . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |
|   |   |
|
|
|
|   |
|   |
|
|
|   |   |
|   |   | . | . | . |   |   |   |   |
|
|
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
L | S | V | Q | T | G | S | D | I | P | Q | R | D | Y | I | K | R | E | V | M | V | P | M | R | D | G | V | K | L | Y | T | V | I | V | I | P | K | N | . |
. |
. |
A | R | N | A | P | I | L | L | T | R | T | P | Y | N | A | K | G | R | A | N | R | V | P | N | A | L | T | M | R | E | V | L | P | Q | G | D | D | V | F |
Template Known Secondary structure |   |
T | T |
|
|
| S |
| S |
|
|
|
| S |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  | T | T | . | . | . |
|
| S |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  | T |
| S | S | T | T |
| S | S |  |  |  |  | S |
| G | G | G |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
53 | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | |
|
|
. | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . |
  |
  |   |
471 | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | D | R | G | F | V | Y | A | I | V | H | V | R | G | G | G | E | L | G | Q | Q | W | Y | . |
. |
. |
. |
. |
E | D | G | K | F | L | K | K | K | N | T | F | N | D | Y | L | D | A | C | D | A | L | L | K | L | G | Y | G | S | P | S | L | C | Y | A | M | G | G | S | A | G | G | M | L | M | G | V | A | I | N | Q | R |
Query Conservation |   |
  |   |   |
|   |   |
|   |   |   |
|   |
|
|
|   |
|   |
|   |   |
|   | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |
|
|   |   |
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|
|
|
|   |
|   |   |   |   |   |
|
|
|
|   |   |
|   |
|
|
|
|   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
V | E | G | G | Y | I | R | V | F | Q | D | I | R | G | K | Y | G | S | Q | G | D | Y | V | M | T | R | P | P | H | G | P | L | N | P | T | K | T | D | E | T | T | D | A | W | D | T | V | D | W | L | V | H | N | V | P | E | S | N | G | R | V | G | M | T | G | S | S | Y | E | G | F | T | V | V | M | A | L | L | D | P |
Template Known Secondary structure |   |
 |  | T | T |
|  |  |  |  |  |  |
| T | T | S | T | T |
|
| S |
|
|
| T | T |
|
|
| S | B | T | T | B |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
139 | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . |
  |
  |   |
546 | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
P | E | L | F | H | G | V | I | A | Q | V | P | F | V | D | V | V | T | T | M | L | D | E | S | I | P | L | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | G | E |
Query Conservation |   |
|
|
|
|   |
|   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |
|   |
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
H | P | A | L | K | V | A | A | P | E | S | P | M | V | D | G | W | M | G | D | D | W | F | H | Y | G | A | F | R | Q | G | A | F | D | Y | F | V | S | Q | M | T | A | R | G | G | G | N | D | I | P | R | R | D | A | D | D | Y | T | N | F | L | K | A | G | S | A | G | S | F | A | T | Q | A | G | L | D | Q | Y | P | F |
Template Known Secondary structure |   |
| T | T |  |  |  |  |  |  |  |  |  |
|
|
| T | T | T | T | S | S | S |  |  | T | T |  |  | B | T | T |  |  |  |  |  |  |  |  |  | S | S | S | S |
|
|
|
|
|
|
| S | S | S |
|  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  | T | T | G | G | G |
|  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
219 | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |
  |   |
577 | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
F | E | E | W | G | N | P | Q | D | P | Q | Y | Y | E | Y | M | K | S | Y | S | P | Y | D | N | V | T | A | Q | A | Y | P | H | L | L | V | T | T | G | L | H | D | S | Q | V | Q | Y | W | E | P | A | K | W | V | A | K | L | R | E | L | K | T | D | D | H | L | L | L | L | C | T | D | M | D | S | G | H | G | G | K | . |
Query Conservation |   |
  |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
| . |   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |
|
|   |   |   |   |   |   |   | . |   |   |   |
|   |
|
|
|
| . |   |
|   |   |   |   |
Template Sequence |   |
W | Q | R | M | H | A | H | P | A | Y | D | A | F | W | Q | G | Q | A | L | D | K | I | L | A | Q | R | K | P | T | V | P | . |
M | L | W | E | Q | G | L | W | D | Q | E | D | M | W | G | A | . |
I | H | A | W | Q | A | L | K | D | A | D | V | K | A | . |
P | N | T | L | V | M | G | P | W | . |
R | H | S | G | V | N |
Template Known Secondary structure |   |
 |  |  |  |  | T |
|
| S | S | S |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |
|
|
| S |
| . |  |  |  |  |  |  | T | T |
| S | S |
| S | S |  |  | . |  |  |  |  |  |  |  |  |  | T | T |
| S | S | . |
|  |  |  |  |  |  | S |
| . |
| T | T | G | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
. | . | . | . | 350 | . | . | . | . | . | . | . | . | . | |
360 | . | . | . | . | . | . | . | . | |
. | 370 | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
656 | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | G | R | F | K | S | Y | E | G | V | A | M | E | Y | A | F | L | V | A | L | A | Q | G | T | L | P | A | T | P | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
Template Sequence |   |
Y | N | G | S | T | L | G | P | L | E | F | E | G | D | T | A | H | Q | Y | R | R | D | V | F | R | P | F | F | D | E | Y | L | K | P | G | S | A | S | V | H | L |
Template Known Secondary structure |   |
S |
|
| S |  |  | T | T |  |  |
| S | S |
|  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  | S | T | T |
|
|
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
375 | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . |
  |