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Job DescriptionP24555
Confidence100.00%DateThu Jan 5 11:41:42 GMT 2012
Rank10Aligned Residues586
% Identity16%Templatec1z68A_
PDB info PDB header:lyaseChain: A: PDB Molecule:fibroblast activation protein, alpha subunit; PDBTitle: crystal structure of human fibroblast activation protein alpha
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   62.......70.........80.........90.........100.........110.........120.........130.........140.
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Query Sequence  LKEIIDRIPQREVSAPYIKNGYRYRHIYEPGCEYAIYQRQSAFSEEWDEWETLLDANKRAAHSEFYSMGGMAITPDNTIM
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Template Sequence  LKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLY. . . . . . . NIETGQSYTILSNRTMKSVNAS. . . . NYGLSPDRQFV
Template Known Secondary structure  TTT






SSSS
TTS
.......SSS


TTT
S....
TTSS
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   44.....50.........60.........70......... 80.........90.........100. ........110..
 
   142.......150.. .......160....... ..170.........180.........190.........200.........210.....
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Query Sequence  ALAEDFLSRRQ. . . . YGIRFRNLETGNWYP. ELLDNVEPSFVWANDSWIFYYVRKHPVTLLPYQVWRHAIGTPASQDKL.
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Template Sequence  YLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQN. . . . . . . NIYLKQRPGDPPFQITF
Template Known Secondary structure 
SSS
TTTT

SS


SSB


SSTT
TT.......SSTTS




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   113......120.........130.........140.........150.........160........ .170.........180.....
 
   216...220.........230.........240..... ....250..
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Query Sequence  . . . . . . . . . . . . . . IYEEKDDTYYVSLHKTTSKHYVVIHLASAT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . TSEVRLL
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Template Sequence  NGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIF
Template Known Secondary structure 

BTTTSS

TT
SS


TTSS
TTS


SSSS


BTTS


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   186...190.........200.........210.........220.........230.........240.........250.........260.....
 
   253......260......... 270.........280.........290.........300.........310.
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Query Sequence  DAEMADAEPFVFLPRRK. . . . . . . . . . DHEYSLDHYQHRFYLRSNRHGKNFGLYRTRMRDEQQWEELIP. . . . . . . . . . .
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Template Sequence  IIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTG
Template Known Secondary structure  SS






TS
SSSSSSTT
SSSSS

GGG
SSS
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   266...270.........280.........290.........300.........310.........320.........330.........340.....
 
   312.......320.........330.........340.........350........
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Query Sequence  . . . PRENIMLEGFTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Conservation                                               
     
                          
 
Template Sequence  WAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIY
Template Known Secondary structure 
SSSSS




TTSS

TTS
SS
STT

S
SSS

SSS
GGG
TT
B
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   346...350.........360.........370.........380.........390.........400.........410.........420.....
 
   359360.........370.........380.........390.........400.........410..... .
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Query Sequence  . . . . . . . . . . . . . . . . . . . . AYVTWIAYNPEPETARLRYGYSSMTTPDTLFELDMDTGERRVLKQTEVPGFYAANYR. . S
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Template Conservation   
                            
 

       
    
               
                 
Template Sequence  RISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPK
Template Known Secondary structure 
SSSS

SSTTTTTTTB
B
GGGSS

BSS

SSS



TTSB


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   426...430.........440.........450.........460.........470.........480.........490.........500.....
 
   417..420.........430.........440.........450.........460.. .......470.........480.........490...
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Query Sequence  EHLWIVARDGVEVPVSLVYHRKHFRKGHNPLLVYGYGSYGASIDAD. . . FSFSRLSLLDRGFVYAIVHVRGGGELGQQWY
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Template Conservation          

  
 
 
  
         
 
    


                     
  
     


   
    
Template Sequence  EEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLL
Template Known Secondary structure  TT
TT

SSS



TTB









TT


TTBSSS
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   506...510.........520.........530.........540.........550.........560.........570.........580.....
 
   494.....500.........510.........520.........530.........540.........550.........560.........570...
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Query Sequence  EDGKFLKKKNTFNDYLDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVDVVTTMLDESIPLT
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Template Sequence  YAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYY. . . . . . . AS
Template Known Secondary structure  GGGTT
TTTTS
TTTSSS

SS



TTTS.......B
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   586...590.........600.........610.........620.........630.........640.........650...... ..
 
   574.....580.........590.........600.........610.........620.........630.........640.........650...
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Query Sequence  TGEFEEWGNPQDPQYYEYMKSYSPYDNVTAQAYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDDHLLLLCTDMDSGHG
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Template Sequence  VYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVD. . . FQAMWYSDQNHG
Template Known Secondary structure 

SSTTTTT
SGGGGGGGTTSTT
SSS
TTT

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TT

TT
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   659660.........670.........680.........690.........700.........710.........720... ......730.....
 
   654.....660.........670.......
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Query Sequence  GKSGRFKSYEGVAMEYAFLVALAQ
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Template Sequence  LSG. . LSTNHLYTHMTHFLKQCFS
Template Known Secondary structure 

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   736.. .740.........750.......
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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