Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	I	H	K	K	G	Q	A	H	W	E	G	D	I	K	R	G	K	G	T	V	S	T	E	S	G	V	L	N	Q	Q	P	Y	G	F	N	T	R	F	E	G	E	K	G	T	N	P	E	E	L	I	G	A	A	H	A	A	C	F
Secondary structure
SS confidence
Disorder		?	?												?		?	?	?	?						?			?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	M	A	L	S	L	M	L	G	E	A	G	F	T	P	T	S	I	D	T	T	A	D	V	S	L	D	K	V	D	A	G	F	A	I	T	K	I	A	L	K	S	E	V	A	V	P	G	I	D	A	S	T	F	D	G	I	I	Q	K
Secondary structure
SS confidence
Disorder																														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.
Sequence		A	K	A	G	C	P	V	S	Q	V	L	K	A	E	I	T	L	D	Y	Q	L	K	S
Secondary structure
SS confidence
Disorder																							?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1qwi chain A Region: 2 - 143 Aligned: 142 Modelled: 142 Confidence: 100.0% Identity: 98% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1nye chain D Region: 1 - 143 Aligned: 143 Modelled: 143 Confidence: 100.0% Identity: 100% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1ukk chain A Region: 5 - 142 Aligned: 136 Modelled: 138 Confidence: 100.0% Identity: 39% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 3eer chain A Region: 5 - 141 Aligned: 131 Modelled: 137 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: A: PDB Molecule:organic hydroperoxide resistance protein, putative; PDBTitle: high resolution structure of putative organic hydroperoxide resistance2 protein from vibrio cholerae o1 biovar eltor str. n16961 Phyre2 PDB 2bjo chain A Region: 5 - 142 Aligned: 133 Modelled: 138 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: A: PDB Molecule:organic hydroperoxide resistance protein ohrb; PDBTitle: crystal structure of the organic hydroperoxide resistance2 protein ohrb of bacillus subtilis Phyre2 PDB 2onf chain A domain 1 Region: 4 - 142 Aligned: 134 Modelled: 139 Confidence: 100.0% Identity: 16% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1n2f chain A Region: 1 - 142 Aligned: 136 Modelled: 142 Confidence: 100.0% Identity: 22% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1usp chain A Region: 4 - 142 Aligned: 134 Modelled: 139 Confidence: 100.0% Identity: 25% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1vla chain A Region: 4 - 141 Aligned: 134 Modelled: 136 Confidence: 100.0% Identity: 17% Fold: OsmC-like Superfamily: OsmC-like Family: YhfA-like Phyre2 PDB 2pn2 chain A domain 1 Region: 6 - 141 Aligned: 129 Modelled: 136 Confidence: 99.9% Identity: 9% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 2opl chain A domain 1 Region: 4 - 142 Aligned: 137 Modelled: 139 Confidence: 99.9% Identity: 13% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1zb8 chain B Region: 5 - 141 Aligned: 131 Modelled: 137 Confidence: 99.9% Identity: 24% PDB header:oxidoreductase Chain: B: PDB Molecule:organic hydroperoxide resistance protein; PDBTitle: crystal structure of xylella fastidiosa organic peroxide resistance2 protein Phyre2 PDB 1lql chain A Region: 1 - 142 Aligned: 134 Modelled: 142 Confidence: 99.9% Identity: 19% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1lql chain E Region: 1 - 142 Aligned: 134 Modelled: 142 Confidence: 99.9% Identity: 19% PDB header:unknown function Chain: E: PDB Molecule:osmotical inducible protein c like family; PDBTitle: crystal structure of osmc like protein from mycoplasma2 pneumoniae Phyre2 PDB 2d7v chain A domain 1 Region: 4 - 139 Aligned: 136 Modelled: 136 Confidence: 99.9% Identity: 15% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 2ql8 chain A Region: 5 - 141 Aligned: 126 Modelled: 137 Confidence: 99.9% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:putative redox protein; PDBTitle: crystal structure of a putative redox protein (lsei_0423) from2 lactobacillus casei atcc 334 at 1.50 a resolution Phyre2 PDB 1ml8 chain A Region: 6 - 142 Aligned: 125 Modelled: 137 Confidence: 99.9% Identity: 14% Fold: OsmC-like Superfamily: OsmC-like Family: YhfA-like Phyre2 PDB 2egt chain A Region: 5 - 142 Aligned: 124 Modelled: 125 Confidence: 99.9% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein aq_1549; PDBTitle: crystal structure of hypothetical protein (aq1549) from aquifex2 aeolicus Phyre2 PDB 3cje chain A Region: 6 - 142 Aligned: 135 Modelled: 137 Confidence: 99.9% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:osmc-like protein; PDBTitle: crystal structure of an osmc-like hydroperoxide resistance protein2 (jann_2040) from jannaschia sp. ccs1 at 1.70 a resolution Phyre2 PDB 3c7b chain B domain 2 Region: 100 - 137 Aligned: 38 Modelled: 38 Confidence: 21.1% Identity: 8% Fold: Ferredoxin-like Superfamily: Nitrite/Sulfite reductase N-terminal domain-like Family: DsrA/DsrB N-terminal-domain-like Phyre2 1 d1qwia_ 2 d1nyed_ 3 d1ukka_ 4 c3eerA_ 5 c2bjoA_ 6 d2onfa1 7 d1n2fa_ 8 d1uspa_ 9 d1vlaa_ 10 d2pn2a1 11 d2opla1 12 c1zb8B_ 13 d1lqla_ 14 c1lqlE_ 15 d2d7va1 16 c2ql8A_ 17 d1ml8a_ 18 c2egtA_ 19 c3cjeA_ 20 d3c7bb2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1qwia_ 100.0 98 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 2 d1nyed_ 100.0 100 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 3 d1ukka_ 100.0 39 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 4 c3eerA_ 100.0 23 PDB header:oxidoreductase Chain: A: PDB Molecule:organic hydroperoxide resistance protein, putative; PDBTitle: high resolution structure of putative organic hydroperoxide resistance2 protein from vibrio cholerae o1 biovar eltor str. n16961 5 c2bjoA_ 100.0 28 PDB header:oxidoreductase Chain: A: PDB Molecule:organic hydroperoxide resistance protein ohrb; PDBTitle: crystal structure of the organic hydroperoxide resistance2 protein ohrb of bacillus subtilis 6 d2onfa1 100.0 16 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 7 d1n2fa_ 100.0 22 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 8 d1uspa_ 100.0 25 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 9 d1vlaa_ 100.0 17 Fold:OsmC-like Superfamily:OsmC-like Family:YhfA-like 10 d2pn2a1 99.9 9 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 11 d2opla1 99.9 13 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 12 c1zb8B_ 99.9 24 PDB header:oxidoreductase Chain: B: PDB Molecule:organic hydroperoxide resistance protein; PDBTitle: crystal structure of xylella fastidiosa organic peroxide resistance2 protein 13 d1lqla_ 99.9 19 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 14 c1lqlE_ 99.9 19 PDB header:unknown function Chain: E: PDB Molecule:osmotical inducible protein c like family; PDBTitle: crystal structure of osmc like protein from mycoplasma2 pneumoniae 15 d2d7va1 99.9 15 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 16 c2ql8A_ 99.9 25 PDB header:oxidoreductase Chain: A: PDB Molecule:putative redox protein; PDBTitle: crystal structure of a putative redox protein (lsei_0423) from2 lactobacillus casei atcc 334 at 1.50 a resolution 17 d1ml8a_ 99.9 14 Fold:OsmC-like Superfamily:OsmC-like Family:YhfA-like 18 c2egtA_ 99.9 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein aq_1549; PDBTitle: crystal structure of hypothetical protein (aq1549) from aquifex2 aeolicus 19 c3cjeA_ 99.9 19 PDB header:oxidoreductase Chain: A: PDB Molecule:osmc-like protein; PDBTitle: crystal structure of an osmc-like hydroperoxide resistance protein2 (jann_2040) from jannaschia sp. ccs1 at 1.70 a resolution 20 d3c7bb2 21.1 8 Fold:Ferredoxin-like Superfamily:Nitrite/Sulfite reductase N-terminal domain-like Family:DsrA/DsrB N-terminal-domain-like 21 d1gsma1 not modelled 11.7 25 Fold:Immunoglobulin-like beta-sandwich Superfamily:Immunoglobulin Family:I set domains 22 d1zbsa2 not modelled 11.5 50 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like 23 d1szpa1 not modelled 10.7 22 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 24 c3m05A_ not modelled 8.7 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pepe_1480; PDBTitle: the crystal structure of a functionally unknown protein2 pepe_1480 from pediococcus pentosaceus atcc 25745 25 d1zxoa1 not modelled 8.6 40 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like 26 d1szpb1 not modelled 8.6 22 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 27 d1ozbg_ not modelled 7.4 11 Fold:SecB-like Superfamily:SecB-like Family:Bacterial protein-export protein SecB 28 c3luyA_ not modelled 7.3 13 PDB header:isomerase Chain: A: PDB Molecule:probable chorismate mutase; PDBTitle: putative chorismate mutase from bifidobacterium adolescentis 29 d1b22a_ not modelled 7.3 26 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 30 c1b22A_ not modelled 7.3 26 PDB header:dna binding protein Chain: A: PDB Molecule:dna repair protein rad51; PDBTitle: rad51 (n-terminal domain) 31 d1p42a1 not modelled 7.2 29 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC 32 c3mwbA_ not modelled 7.0 11 PDB header:lyase Chain: A: PDB Molecule:prephenate dehydratase; PDBTitle: the crystal structure of prephenate dehydratase in complex with l-phe2 from arthrobacter aurescens to 2.0a 33 d2fgca2 not modelled 6.8 21 Fold:Ferredoxin-like Superfamily:ACT-like Family:IlvH-like 34 c2cx8B_ not modelled 6.5 21 PDB header:transferase Chain: B: PDB Molecule:methyl transferase; PDBTitle: crystal structure of methyltransferase with ligand(sah) 35 d2v4jb2 not modelled 6.1 8 Fold:Ferredoxin-like Superfamily:Nitrite/Sulfite reductase N-terminal domain-like Family:DsrA/DsrB N-terminal-domain-like 36 d2pc6a2 not modelled 5.8 12 Fold:Ferredoxin-like Superfamily:ACT-like Family:IlvH-like 37 d1v6za2 not modelled 5.7 21 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:YggJ C-terminal domain-like 38 c2egwB_ not modelled 5.5 16 PDB header:rna methyltransferase Chain: B: PDB Molecule:upf0088 protein aq_165; PDBTitle: crystal structure of rrna methyltransferase with sah ligand 39 c1vhyB_ not modelled 5.5 16 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein hi0303; PDBTitle: crystal structure of haemophilus influenzae protein hi0303, pfam2 duf558

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0