|   |
2 | . | . | . | |
|
|
|
. | . | |
. | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 40 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
| . | . | . | . |
|
| . |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
| . |
. |
. |
. |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | D | T | T | . |
. |
. |
. |
L | P | . |
L | T | D | I | H | R | H | L | D | G | N | I | R | P | Q | T | I | L | E | L | G | R | Q | Y | N | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | L | P | A | Q | S | L | E | T | L | I | P |
Query Conservation |   |
|   |
|   | . | . | . | . |
|
| . |
|
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
| . | . | . | . |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | D | V | A | G | K | V | V | S | P | G | F | I | D | S | H | T | H | D | D | N | Y | L | L | K | H | R | D | M | T | P | K | I | S | Q | G | V | T | T | V | V | T | G | N | C | G | I | S | L | A | P | L | A | H | A | N | P | P | A | P | L | D | L | L | D | E | G | G | S | F | R | F | A | R | F | S | D | Y | L | E |
Template Known Secondary structure |   |
 |  |
| T | T |
|  |  |  |  |
|  |  |  | S | S |
|
|
| T | T |  |  |  |  |
| T | T |
|  |  |  |  | T | T | T |  |  |  |  |  |  | S |
| T | T |
|
| S |
| S |  |  |
| S | S |
|
| T | T | G | G | G | G |
| S | S | S |
|
|  |  | S | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
52 | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . |
  |
  |   |
46 | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | V | Q | V | I | A | N | E | P | D | . |
. |
. |
. |
. |
L | V | S | F | L | T | K | L | D | W | G | V | K | V | L | A | S | L | D | A | C | R | R | V | A | F | E | N | I | E | D | A | A | R | H | G | L | H | Y | V | E | L | R | F | S | P | G | Y | M | A | M | A | H | Q | L | P | V | A | G | V | V | E | A | V | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   | . | . | . | . | . |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |
Template Sequence |   |
A | L | R | A | A | P | P | A | V | N | A | A | C | M | V | G | H | S | T | L | R | A | A | V | M | P | D | L | R | R | E | A | T | A | D | E | I | Q | A | M | Q | A | L | A | D | D | A | L | A | S | G | A | I | G | I | S | T | G | A | F | Y | P | . |
. |
. |
P | A | A | H | A | S | T | E | E | I | I | E | . |
. |
. |
Template Known Secondary structure |   |
 |  |  |  | S |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| T | T | S | G | . | . | . | G | G | T | T |
|
|  |  |  |  |  |  | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |  | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
132 | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | |
|
|
. | . | . | . | . | . | 200 | . | . | . | . | . | |
|
|
  |
  |   |
121 | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | |
. | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | G | V | R | E | G | C | R | T | F | G | V | Q | A | K | L | I | G | I | M | S | R | T | F | G | E | A | A | C | Q | Q | E | L | E | A | F | L | A | H | R | D | Q | I | T | A | L | D | L | A | G | D | E | L | . |
G | F | P | G | S | L | F | L | S | H | F | N | R | A | R | D | A | G | W | H | I | T | V | H | A | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |
|   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
V | C | R | P | L | I | T | H | G | G | V | Y | A | T | H | M | R | D | E | G | E | H | I | V | Q | A | L | E | E | T | F | R | I | G | R | E | L | D | V | P | V | V | I | S | H | H | K | V | M | G | K | L | N | F | G | R | S | K | E | T | L | A | L | I | E | A | A | M | A | S | Q | D | V | S | L | D | A | Y |
Template Known Secondary structure |   |
. | . |  |  | T |  |  |  |  |  | T |
|  |  |  |  |
|
| S |
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |
| S |
|
|
|
| S | G | G | G | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |
|
Template Predicted Secondary structure |   |
. | . |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
  |
  |   |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | |
|
|
|
. | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  | . | . | . | . |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | A | G | P | E | S | I | W | Q | A | I | R | E | L | G | A | E | R | I | G | H | G | V | K | A | I | E | D | R | A | . |
. |
. |
. |
L | M | D | F | L | A | E | Q | Q | I | G | I | E | S | C | L | T | S | N | I | Q | T | S | T | V | A | E | L | A | A | H | P | L | K | T | F | L | E | H | G | I | R | A | S | I |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |
|   |   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |
|
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | Y | V | A | G | S | T | M | L | K | Q | D | R | V | L | L | A | G | R | T | L | I | T | W | C | K | P | Y | P | E | L | S | G | R | D | L | E | E | I | A | A | E | R | G | K | S | K | Y | D | V | V | P | E | L | Q | P | A | G | A | I | Y | F | M | M | D | E | P | D | V | Q | R | I | L | A | F | G | P | T | M | I |
Template Known Secondary structure |   |
S |
| S |
|  |  |  |  |
|
|
|
| T | T | T | T | S | S |
|  |  |  |  |  |  | S | S |
| G | G | G | T | T |
| B |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | S | T | T |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
284 | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . |
  |
  |   |
276 | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 300 | . | . | . | . | |
. | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | T | D | D | P | G | V | Q | G | V | D | I | I | H | E | Y | T | V | A | A | P | . |
. |
. |
. |
. |
. |
. |
. |
A | A | G | L | S | R | E | Q | . |
I | R | Q | A | Q | I | N | G | L | E | M | A | F | L | S | A |
Query Conservation |   |
  |
|
|
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |
|   |   | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   | . |
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
Template Sequence |   |
G | S | A | G | L | P | H | D | E | R | P | H | P | R | L | W | G | T | F | P | R | V | L | G | H | Y | S | R | D | L | G | L | F | P | L | E | T | A | V | W | K | M | T | G | L | T | A | A | K | F | G | L | A | E |
Template Known Secondary structure |   |
|
|
|
|
| T | T |
| S | S |
|
| T |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| T |
| S | S |
|  |  |  |  |  |  | T | T | T |  |  |  |  |  |  | T | T |
| T | T |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
364 | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . |
  |