|   |
312 | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | |
. | . | 350 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  | . |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | V | A | V | I | G | A | G | P | A | G | L | G | C | A | D | I | L | A | R | A | G | V | Q | V | D | V | F | D | R | H | P | E | I | G | G | . |
M | L | T | F | G | I | P | P | F | K | . |
. |
. |
. |
. |
. |
. |
L | D | K | T | V | L | S | Q | R | R | E | I | F | T | A | M | G | I | D | F | H | L | N | C | E | I |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|   |
|   |   |
|
|
|   |
|
|   |   |   |   |
|
| . |   |
|   |   |
|
|
|   |   |   | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | V | V | V | V | G | G | G | I | S | G | M | A | A | A | K | L | L | H | D | S | G | L | N | V | V | V | L | E | A | R | D | R | V | G | G | R | T | Y | T | L | R | N | Q | K | V | K | Y | V | D | L | G | G | S | Y | V | G | P | T | Q | N | R | I | L | R | L | A | K | E | L | G | L | E | T | Y | K | V | N | E | V |
Template Known Secondary structure |   |
|  |  |  |  |
|
| B |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  | S | S | S | S | S | B | T | T |
|
|  |  |
|
| T | T | T | S |
|  |  | S | S |
|
|  |  |
| T | T |
|  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |
|
|
| S |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . |
  |
  |   |
384 | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | R | D | I | T | F | S | D | L | T | S | E | Y | D | A | V | F | I | G | V | G | T | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | M | M | R | A | D | L | P | H | E | D | A | P | G | V | I | Q | A | L | P | F | L | T | A | H | T | R | Q | L | M | G | L | P | E | S | E | E | Y | P | L | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|
|   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | R | L | I | H | H | V | K | G | K | S | Y | P | F | R | G | P | F | P | P | V | W | N | P | I | T | Y | L | D | H | N | N | F | W | R | T | M | D | D | M | G | R | E | I | P | S | D | A | P | W | K | A | P | L | A | E | E | W | D | N | M | T | M | K | E | L | L | D | K | L | C | W | T | E | S | A | K | Q | L | A |
Template Known Secondary structure |   |
S |
|  |  |  |  |  | T | T |  |  |  |  |  |
| S | S | S |
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| T | T |
| G | G | G | S | T | T |  |  |  |  |  | T | S | B |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
86 | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . |
  |
  |   |
448 | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | |
|
|
|
490 | . | . | . | . | . | . | . | . | . | 500 | . | . | |
. | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | V | E | G | K | R | V | V | V | L | G | G | G | D | T | T | M | D | C | L | R | T | S | I | R | L | N | A | A | S | V | T | C | A | Y | R | R | D | E | V | S | M | . |
. |
. |
. |
P | G | S | R | K | E | V | V | N | A | R | E | E | . |
G | V | E | F | Q | F | N | V | Q | P | Q | Y | I | A | C | D | E | D | G | R |
Query Conservation |   |
  |   |   |
|
|   |
|
|
|
|
|
|
|   |   |
|   |
|   |
|   |   |   |   |
|   |
|
|   |   |
|
|
|
|   |
|   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |
|
|   |   |
|   |
|
| . |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . |
Template Sequence |   |
T | L | F | V | N | L | C | V | T | A | E | T | H | E | V | S | A | L | W | F | L | W | Y | V | K | Q | C | G | G | T | T | R | I | I | S | T | T | N | G | G | Q | E | R | K | F | V | G | G | S | G | Q | V | S | E | R | I | M | D | L | L | G | D | R | V | K | L | E | R | P | V | I | Y | I | D | Q | T | R | E | . |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | S | S |
| T | T | T | S | B |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |
| S | T | T | S | T | T | S |  |  |  | T | T |
| T |  |  |  |  |  |  |  |  |  |  |  | G | G | G |  |  |  | S |
|
|  |  |  |  |  |
| S | S | S | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
166 | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | |
|
  |
  |   |
523 | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | A | V | G | L | I | R | T | A | M | G | E | P | G | P | D | G | R | R | R | P | R | P | V | A | G | S | E | F | E | L | P | A | D | V | L | I | M | A | F | . |
. |
. |
. |
. |
. |
. |
. |
G | F | Q | A | H | A | M | P | W | L | Q | G | S | G | I | K | L | D | K | W | G | L | I | Q | T | G | D | V | G | Y | L |
Query Conservation |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|   |
|
| . | . | . | . | . | . | . | . |
|   |   |
|   |   |   |   |
|
|   |   |   |
|
|   |
|
|   |   |
|   |
|   |
|
|   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |
|   |   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | V | L | V | E | T | L | N | H | E | M | Y | E | A | K | Y | V | I | S | A | I | P | P | T | L | G | M | K | I | H | F | N | P | P | L | P | M | M | R | N | Q | M | I | T | R | V | F | P | P | G | I | L | T | Q | Y | G | . |
. |
. |
R |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |  |  |  |  |  | T | T | S |
|  |  |  |  | S |  |  |  |  |
| S |
| G | G | G | G | G | G | S |  |  |  | S |
|
|
|  |  |  |  |  |  | T | T |
|
|
|
| T | T |  |  |  |  |  | G | . | . | . | G |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
|
|
300 |
  |
  |   |
595 | . | . | . | . | 600 | . | . | . | . | . | . | . | . | |
|
. | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | T | Q | T | H | L | K | K | V | F | A | G | G | D | . |
. |
A | V | H | G | A | D | L | V | V | T | A | M | A | A | G | R | Q | A | A | R | D | M | L | T | L | F | D |
Query Conservation |   |
  |   |   |
|
|   |
|
|
|
|
|
|
|
| . | . |
|   |   |
|   |   |   |
|
|   |
|
|   |   |
|
|   |
|
|   |   |
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |
Template Sequence |   |
V | L | R | Q | P | V | D | R | I | Y | F | A | G | T | E | T | A | T | H | W | S | G | Y | M | E | G | A | V | E | A | G | E | R | A | A | R | E | I | L | H | A | M | G |
Template Known Secondary structure |   |
G | T | T |
|
| B | T | T |  |  |  |
| S | G | G | G |
| S | S | S | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
413 | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . |
  |