Job Description Q46820 Confidence 100.00% Date Thu Jan 5 12:34:45 GMT 2012 Rank 1 Aligned Residues 438 % Identity 31% Template c1gthD_ PDB info PDB header:oxidoreductase Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase; PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil Resolution 2.25 Å

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		189	190	.	.	.	.	.	.	.		.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.
Predicted Secondary structure											.
Query SS confidence											.
Query Sequence		T	H	F	G	E	I	Y	C	G	.	L	D	P	Q	Q	A	T	Y	E	S	D	R	C	V	Y	C	A	E	K	A	N	C	N	W	H	C	P	L	H	N	A	I	P	D	Y	I	R	L	V	Q	E	G	K	I	I	E	A	A	E	L	C	H	Q	T	S	S	L	P	E	I	C	G	R	V	C	P	Q	D	R	L
Query Conservation											.
Alig confidence											.																				.
Template Conservation																															.
Template Sequence		N	N	F	D	D	I	K	H	T	T	L	G	E	R	G	A	L	R	E	A	M	R	C	L	K	C	A	D	A	.	P	C	Q	K	S	C	P	T	H	L	D	I	K	S	F	I	T	S	I	S	N	K	N	Y	Y	G	A	A	K	M	I	F	S	D	N	P	L	G	L	T	C	G	M	V	C	P	T	S	D	L
Template Known Secondary structure		T							T	T																		T	T		.					T	S	T	T													T	T														T	T										G	G	G	S
Template Predicted Secondary structure																															.
Template SS confidence
		57	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.		.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.
		268	.	270	.	.	.	.	.	.	.	.	.		280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.									.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.		.	.
Predicted Secondary structure														.																														.	.	.	.	.	.	.	.																												.
Query SS confidence														.																														.	.	.	.	.	.	.	.																												.
Query Sequence		C	E	G	A	C	T	L	K	D	H	S	G	.	A	V	S	I	G	N	L	E	R	Y	I	T	D	T	A	L	A	M	G	W	R	P	D	V	S	K	V	V	P	.	.	.	.	.	.	.	.	R	S	E	K	V	A	V	I	G	A	G	P	A	G	L	G	C	A	D	I	L	A	R	A	G	V	Q	.	V	D
Query Conservation														.																														.	.	.	.	.	.	.	.																												.
Alig confidence														.																														.	.	.	.	.	.	.	.																												.
Template Conservation
Template Sequence		C	V	G	G	C	N	L	Y	A	T	E	E	G	S	I	N	I	G	G	L	Q	Q	F	A	S	E	V	F	K	A	M	N	I	P	Q	I	R	N	P	C	L	P	S	Q	E	K	M	P	E	A	Y	S	A	K	I	A	L	L	G	A	G	P	A	S	I	S	C	A	S	F	L	A	R	L	G	Y	S	D	I	T
Template Known Secondary structure		G	G	G	G		G	G	G	G	S	T	T																				T				B			T	T	S			G	G	G	S		G	G	G	G									S														T
Template Predicted Secondary structure
Template SS confidence
		136	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.
		338	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.		.	.	.	.	390	.	.	.	.	.		.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.
Predicted Secondary structure																																																		.											.
Query SS confidence																																																		.											.
Query Sequence		V	F	D	R	H	P	E	I	G	G	M	L	T	F	G	I	P	P	F	K	L	D	K	T	V	L	S	Q	R	R	E	I	F	T	A	M	G	I	D	F	H	L	N	C	E	I	G	R	.	D	I	T	F	S	D	L	T	S	E	.	Y	D	A	V	F	I	G	V	G	T	Y	G	M	M	R	A	D	L	P	H
Query Conservation																																																		.											.
Alig confidence																																																		.											.
Template Conservation
Template Sequence		I	F	E	K	Q	E	Y	V	G	G	L	S	T	S	E	I	P	Q	F	R	L	P	Y	D	V	V	N	F	E	I	E	L	M	K	D	L	G	V	K	I	I	C	G	K	S	L	S	E	N	E	I	T	L	N	T	L	K	E	E	G	Y	K	A	A	F	I	G	I	G	L	P	E	P	K	T	D	D	I	F	Q
Template Known Secondary structure					S	S	S	S		S	T					T	S		T	T	T	S														T	T	T						S			B	S	T	T	S	B								T	T																	G	G	G	T
Template Predicted Secondary structure
Template SS confidence
		216	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.
		416			.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.
Predicted Secondary structure			.	.
Query SS confidence			.	.
Query Sequence		E	.	.	D	A	P	G	V	I	Q	A	L	P	F	L	T	A	H	T	R	Q	L	M	G	L	P	E	S	E	E	Y	P	L	T	D	V	E	G	K	R	V	V	V	L	G	G	G	D	T	T	M	D	C	L	R	T	S	I	R	L	N	A	A	S	V	T	C	A	Y	R	R	D	E	V	S	M	P	G	S	R
Query Conservation			.	.
Alig confidence			.	.																			.
Template Conservation																							.
Template Sequence		G	L	T	Q	D	Q	G	F	Y	T	S	K	D	F	L	P	L	V	A	K	S	.	S	K	A	G	M	C	A	C	H	S	P	L	P	S	I	R	G	A	V	I	V	L	G	A	G	D	T	A	F	D	C	A	T	S	A	L	R	C	G	A	R	R	V	F	L	V	F	R	K	G	F	V	N	I	R	A	V	P
Template Known Secondary structure		T			T	T	T	T															.			T	T	T		S	S									S								S													T	T		S							S	S		G	G	G			S
Template Predicted Secondary structure																							.
Template SS confidence
		296	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.		.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.
		494	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	E	V	V	N	A	R	E	E	G	V	E	F	Q	F	N	V	Q	P	Q	Y	I	A	C	D	E	D	G	R	L	T	A	V	G	L	I	R	T	A	M	G	E	P	G	P	D	G	R	R	R	P	R	P	V	A	G	S	E	F	E	L	P	A	D	V	L	I	M	A	F	G	F	Q	A	H	A	M	P	W	L
Query Conservation
Alig confidence																								.																						.	.	.	.	.
Template Conservation																								.																						.	.	.	.	.
Template Sequence		E	E	V	E	L	A	K	E	E	K	C	E	F	L	P	F	L	S	P	R	K	V	.	I	V	K	G	G	R	I	V	A	V	Q	F	V	R	T	E	Q	D	E	T	G	.	.	.	.	.	K	W	N	E	D	E	D	Q	I	V	H	L	K	A	D	V	V	I	S	A	F	G	S	V	L	R	D	P	K	V	K
Template Known Secondary structure										T	T						S							.				S	S	S													S	S	S	.	.	.	.	.															S
Template Predicted Secondary structure																								.																						.	.	.	.	.
Template SS confidence
		375	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.		.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.						.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.
		574	.	.		.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.
Predicted Secondary structure					.
Query SS confidence					.
Query Sequence		Q	G	S	.	G	I	K	L	D	K	W	G	L	I	Q	T	G	D	V	G	Y	L	P	T	Q	T	H	L	K	K	V	F	A	G	G	D	A	V	H	G	A	D	L	V	V	T	A	M	A	A	G	R	Q	A	A	R	D	M	L	T	L	F	D	T	K
Query Conservation					.
Alig confidence					.															.	.	.
Template Conservation																				.	.	.
Template Sequence		E	A	L	S	P	I	K	F	N	R	W	D	L	P	E	V	D	P	.	.	.	E	T	M	Q	T	S	E	P	W	V	F	A	G	G	D	I	V	G	M	A	N	T	T	V	E	S	V	N	D	G	K	Q	A	S	W	Y	I	H	K	Y	I	Q	A	Q
Template Known Secondary structure			T	T	T	T	S		B		T	T	S	S	B				T	.	.	.	T	T		B		S	S	T	T					G	G	G	G	T				S
Template Predicted Secondary structure																				.	.	.
Template SS confidence
		449	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.				.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510