|   |
52 | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
. | 120 | . | . | . | . | . | . | . | . | . | 130 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | H | I | V | E | K | L | C | T | V | A | Q | R | P | D | T | H | G | Y | S | T | S | R | G | I | P | R | L | R | R | A | I | S | R | W | Y | Q | D | R | Y | D | V | E | I | D | P | E | S | E | A | I | V | T | I | G | S | K | E | G | L | A | H | L | M | L | A | T | . |
L | D | H | G | D | T | V | L | V | P | N | P |
Query Conservation |   |
  |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|
|
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   | . |   |   |   |
|
|   |
|
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |
| . | . | . |   |   |   |   |
|
|   |   |   |   |
|
|   |   |
|
|   |   |   |
| . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |
|
|   |   |   |   |
Template Sequence |   |
Y | E | I | K | F | K | F | E | E | I | Y | K | R | N | . |
. |
. |
W | F | I | L | G | D | E | D | K | K | F | E | Q | E | F | A | D | Y | C | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
V | N | Y | C | I | G | C | G | N | G | L | D | A | L | H | L | I | L | K | G | Y | D | I | G | F | G | D | E | V | I | V | P | S | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . |
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . | . | . | . | . | S | S |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T |
|  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
17 | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | |
|
|
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | Y | P | I | H | I | Y | G | A | V | I | A | G | A | Q | V | R | S | V | P | L | V | E | G | V | D | F | F | N | E | L | E | R | A | I | R | E | S | Y | P | K | P | K | M | M | I | L | G | F | P | S | N | P | T | A | Q | C | V | E | L | E | F | F | E | K | V | V | A | L | A | K | R | Y | D | V | L | V | V | H | D |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|   |
|
Template Sequence |   |
T | F | I | A | T | A | L | A | V | S | Y | T | G | A | K | P | I | F | V | E | P | D | I | R | T | Y | N | I | D | . |
. |
. |
. |
P | S | L | I | E | S | A | I | T | E | K | T | K | A | I | I | A | V | H | L | Y | G | Q | P | A | D | . |
. |
. |
M | D | E | I | K | R | I | A | K | K | Y | N | L | K | L | I | E | D |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|  |  | T | T | T | T |  |  |
| . | . | . | . | G | G | G | T | G | G | G |
|
| T | T |  |  |  |  |  |  |  |
| G | G | G | S |
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | |
|
|
|
. | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . |
  |
  |   |
211 | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 280 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | Y | A | D | I | V | Y | D | G | W | K | A | P | S | I | M | Q | V | P | G | A | R | D | V | A | V | E | F | F | T | L | S | K | S | Y | N | M | A | G | W | R | I | G | F | M | V | G | N | K | T | L | V | S | A | L | A | R | I | K | S | Y | . |
. |
. |
. |
. |
. |
. |
. |
H | D | Y | G | T | F | T | P | L | Q |
Query Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | A | Q | A | H | G | S | L | Y | K | G | . |
. |
. |
. |
. |
M | K | V | G | S | L | G | D | A | A | G | F | S | F | Y | P | A | K | N | L | G | S | L | G | D | G | G | A | V | V | T | N | D | K | D | L | A | E | K | I | K | A | L | S | N | Y | G | S | E | K | K | Y | H | H | I | Y | K | G | F | N | S | R | L | D |
Template Known Secondary structure |   |
| T | T |
| T | T |
|  |  | T | T | . | . | . | . | . |  |  | T | T | S | S | S | S |  |  |  |  |  |
|
| T | T | S | T | T |
|
| S | S |
|
|  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  | B | T | T |
| S | B | T | T | B |
|
| S |
|
|
| B |
|
|
|
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
158 | . | 160 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
  |
  |   |
283 | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | A | A | I | A | A | L | E | G | D | Q | Q | C | V | R | D | I | A | E | Q | Y | K | R | R | R | D | V | L | V | K | G | L | H | E | A | G | W | M | V | E | M | P | K | A | S | M | Y | V | W | A | K | I | P | E | P | Y | A | A | M | G | S | L | E | F | A | K | K | L | L | N | E | A | K | V | C | V | S | P | G | I |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| . |   |   |   |
|
|   |   |   |   |   |   |
Template Sequence |   |
E | L | Q | A | G | F | L | R | V | K | L | K | Y | L | D | K | W | N | E | E | R | R | K | I | A | Q | K | Y | I | A | G | I | N | N | P | N | V | I | I | P | V | E | A | D | Y | A | K | H | V | W | . |
Y | T | F | V | I | R | S | E | K | R | D | E | L | Q | K | Y | L | . |
N | N | N | G | I | G | T | L | I | H | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| B | T | T | B | B |
|
|
|
|
| T | T |  |  |
|
|
| . | S |
|
|  |  |  |
| T | T |  |  |  |  |  |  |  |  | . |  |  | T | T | B |
|
| B |
| S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  | . |  |  |
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | |
. | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
300 | . | . | . | . | . | . | . | . | . | 310 |
  |
  |   |
363 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 370 | . | . | . | . | . | . | . | |
|
. | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | F | G | D | Y | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | T | H | V | R | F | A | L | I | . |
. |
E | N | R | D | R | I | R | Q | A | I | R | G | I | K | A | M |
Query Conservation |   |
  |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|
|   |   | . | . |   |   |   |
|   |
|   |   |   |
|   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |
|
|   |   |   |
Template Sequence |   |
P | I | P | I | H | L | Q | Q | A | Y | K | D | L | G | F | K | T | G | N | F | P | I | A | E | K | I | A | N | E | I | L | S | I | P | I | W | Y | G | M | K | N | E | E | I | E | Y | V | I | D | K | I | N | A | W |
Template Known Secondary structure |   |
S | S |
| G | G | G | S | G | G | G | G | G | G |
|
|
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
311 | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
  |