Job Description P77434 Confidence 99.95% Date Thu Jan 5 12:29:17 GMT 2012 Rank 141 Aligned Residues 336 % Identity 14% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		33	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.					.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.
Predicted Secondary structure																																		.	.	.	.
Query SS confidence																																		.	.	.	.
Query Sequence		R	R	G	E	D	I	I	D	F	S	M	G	N	P	D	G	A	T	P	P	H	I	V	E	K	L	C	T	V	A	Q	R	.	.	.	.	P	D	T	H	G	Y	S	T	S	R	G	I	P	R	L	R	R	A	I	S	R	W	Y	Q	D	R	Y	D	V	E	I	D	P	E	S	E	A	I	V	T	I	G	S	K
Query Conservation																																		.	.	.	.
Alig confidence												.																						.	.	.	.																															.	.	.
Template Conservation												.																																																								.	.	.
Template Sequence		N	K	D	E	N	A	I	Y	F	L	.	G	N	S	L	G	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	.	.	.	E	K	E	I	A	L	M	N	A	L	T
Template Known Secondary structure			T	T		B					B	.	T	T	T	S			B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					T			.	.	.	G	G	G					S
Template Predicted Secondary structure												.																																																								.	.	.
Template SS confidence
		63	.	.	.	.	.	.	70	.	.		.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.				.	.	130	.	.	.	.	.	.	.	.
		109	110	.	.	.	.	.	.	.	.	.	120	.				.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.										.	.	.	.	.	.	.	150	.	.	.	.	.	.	.		.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.
Predicted Secondary structure															.	.	.																						.	.	.	.	.	.	.	.	.																.
Query SS confidence															.	.	.																						.	.	.	.	.	.	.	.	.																.
Query Sequence		E	G	L	A	H	L	M	L	A	T	L	D	H	.	.	.	G	D	T	V	L	V	P	N	P	S	Y	P	I	H	I	Y	G	A	V	I	A	.	.	.	.	.	.	.	.	.	G	A	Q	V	R	S	V	P	L	V	E	G	V	D	F	.	F	N	E	L	E	R	A	I	R	E	S	Y	P	K	P	K	M	M
Query Conservation															.	.	.																						.	.	.	.	.	.	.	.	.																.
Alig confidence															.	.	.																						.	.	.	.	.	.	.	.	.																.
Template Conservation
Template Sequence		V	N	L	H	L	L	M	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	V	I
Template Known Secondary structure																S	S	S							T	T																T	T														T	T		S	S														G	G	G
Template Predicted Secondary structure
Template SS confidence
		139	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.
		176	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	L	G	F	P	S	N	P	T	A	Q	C	V	E	L	E	F	F	E	K	V	V	A	L	A	K	R	Y	D	V	L	V	V	H	D	L	A	Y	A	D	I	V	Y	D	G	W	K	A	P	S	I	M	Q	V	P	G	A	R	D	V	A	V	E	F	F	T	L	S	K	S	Y	N	M	A	G	W	R	I	G	F
Query Conservation
Alig confidence																.	.	.																														.	.	.	.	.	.	.	.
Template Conservation																.	.	.																														.	.	.	.	.	.	.	.
Template Sequence		L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	.	.	.	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	N	V	E	L	Y	.	.	.	.	.	.	.	.	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G
Template Known Secondary structure					S	B		T	T	T		B	B			.	.	.											T	T								T	T	T	T	T	T	S				.	.	.	.	.	.	.	.					T								S	S	S	T	T				T	T
Template Predicted Secondary structure																.	.	.																														.	.	.	.	.	.	.	.
Template SS confidence
		219	220	.	.	.	.	.	.	.	.	.	230	.	.				.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.									.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.
		256	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.																										.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.		.	.	.	.	300	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.
Query SS confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.
Query Sequence		M	V	G	N	K	T	L	V	S	A	L	A	R	I	K	S	Y	H	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	Y	G	T	F	T	P	L	Q	V	A	A	I	A	A	L	E	G	D	Q	Q	C	.	V	R	D	I	A	E	Q	Y	K	R	R	R	D	V
Query Conservation																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.
Alig confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.
Template Conservation
Template Sequence		A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y
Template Known Secondary structure						G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		288	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.
		310	.	.	.	.	.	.			.	.	.	320	.	.	.	.	.	.					.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.				.	380
Predicted Secondary structure									.	.											.	.	.	.																																																					.	.	.
Query SS confidence									.	.											.	.	.	.																																																					.	.	.
Query Sequence		L	V	K	G	L	H	E	.	.	A	G	W	M	V	E	M	P	K	A	.	.	.	.	S	M	Y	V	W	A	K	I	P	E	P	Y	A	A	M	G	S	L	E	F	A	K	K	L	L	N	E	A	K	V	C	V	S	P	G	I	G	F	G	D	Y	G	D	T	H	V	R	F	A	L	I	E	.	.	.	N	R
Query Conservation									.	.											.	.	.	.																																																					.	.	.
Alig confidence									.	.											.	.	.	.											.	.	.	.	.										.									.	.	.	.	.	.														.	.	.
Template Conservation																																			.	.	.	.	.										.									.	.	.	.	.	.
Template Sequence		L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	.	.	.	.	.	P	N	K	D	V	F	Q	E	L	.	E	K	R	G	V	V	C	D	.	.	.	.	.	.	K	R	N	P	N	G	I	R	V	A	P	V	P	L	Y	N	S	F
Template Known Secondary structure																	S		S	S	G	G	G	B		S									.	.	.	.	.	T	T								.		T	T	T					.	.	.	.	.	.			T	T	T					B			T	T	T
Template Predicted Secondary structure																																			.	.	.	.	.										.									.	.	.	.	.	.
Template SS confidence
		368	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400						.	.	.	.	.	.	.	.	.		410	.	.	.	.	.	.	.							.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.
		381	.	.	.	.	.	.	.	.	390	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	R	I	R	Q	A	I	R	G	I	K	A	M	F	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	D	V	Y	K	F	T	N	L	L	T	S	I	L	D
Template Known Secondary structure																T
Template Predicted Secondary structure
Template SS confidence
		445	.	.	.	.	450	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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