|   |
34 | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
|
|
|
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | G | E | D | I | I | D | F | S | M | G | N | P | D | . |
. |
. |
. |
G | A | T | P | P | H | I | V | E | K | L | C | T | V | A | Q | R | P | D | T | H | G | Y | S | T | S | R | G | I | P | R | L | R | R | A | I | S | R | W | Y | Q | D | R | Y | D | V | E | I | D | P | E | S | E | A | I | V | T | I | G | S | K | E |
Query Conservation |   |
  |
|   |   |   |
|   |
|   |   |
|   |
|   | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|
|
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |   |   |   |   | . |   |   |   |   |   |   | . |   |   |
|   |   |
|   |
|   |
|   |
Template Sequence |   |
P | N | K | T | M | I | S | L | S | I | G | D | P | T | V | F | G | N | L | P | T | D | P | E | V | T | Q | A | M | K | D | A | L | D | S | G | K | Y | N | G | Y | A | P | S | I | G | F | L | S | S | R | E | E | I | A | S | Y | Y | H | C | P | . |
E | A | P | L | E | A | . |
K | D | V | I | L | T | S | G | C | S | Q |
Template Known Secondary structure |   |
T | T | S |
|
|  |  | S |
|
|
|
| T | T | T | T | S | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S | S |
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |
| B | T | . | T | B |
|
|
| G | . | G | G |  |  |  |  | S |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|  | . |  |  |  |  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
69 | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | |
130 | . | . | . | . | . | |
. | . | . | . | 140 | . | . | . | . | . | . |
  |
  |   |
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | L | A | H | L | M | L | A | T | L | D | H | G | D | T | V | L | V | P | N | P | S | Y | P | I | H | I | Y | G | A | V | I | A | G | A | Q | V | R | S | V | P | L | V | E | G | V | D | F | F | N | E | L | E | R | A | I | R | E | S | Y | P | K | P | K | M | M | I | L | G | F | P | S | N | P | T | A | Q | C | V | E |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | I | D | L | C | L | A | V | L | A | N | P | G | Q | N | I | L | V | P | R | P | G | F | S | L | Y | K | T | L | A | E | S | M | G | I | E | V | K | L | Y | N | L | L | P | E | K | S | W | E | I | D | L | K | Q | L | E | Y | L | I | D | E | K | T | A | C | L | I | V | N | N | P | S | N | P | C | G | S | V | F | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  |  | S |
|
| T |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  | G | G | G | T | T |  |  |
|  |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |  | S | S |
| T | T | T |
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
147 | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
  |
  |   |
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | E | F | F | E | K | V | V | A | L | A | K | R | Y | D | V | L | V | V | H | D | L | A | Y | A | D | I | V | Y | D | G | W | K | A | P | S | I | M | Q | V | P | G | A | R | D | V | A | V | E | F | F | T | L | S | K | S | Y | N | M | A | G | W | R | I | G | F | M | V | G | N | K | T | L | V | S | A | L | A | R | I |
Query Conservation |   |
  |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | R | H | L | Q | K | I | L | A | V | A | A | R | Q | C | V | P | I | L | A | D | E | I | Y | G | D | M | V | F | S | D | C | K | Y | E | P | L | A | T | L | . |
S | T | D | V | P | I | L | S | C | G | G | L | A | K | R | W | L | V | P | G | W | R | L | G | W | I | L | I | H | D | R | R | D | I | F | G | N | E | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| T | T | T | T |
| B |
| S | S | S |
|
|
|
| G | G | G | G | . |
| S | S |
|
|  |  |  |  |  |  | S | T | T | T | T | T |
| G | G | G |
|
|  |  |  |  |  |  |
|
| T | T | S | S |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
227 | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . |
  |
  |   |
270 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | |
. | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | |
|
. |
Predicted Secondary structure |   |
 |  |  |  |
| . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . |
|
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
Query Sequence |   |
K | S | Y | H | D | . |
. |
. |
. |
. |
. |
. |
Y | G | T | F | T | P | L | Q | V | A | A | I | A | A | L | E | G | D | Q | Q | C | V | R | D | I | A | E | Q | Y | K | R | R | R | D | V | L | V | K | G | L | H | E | . |
A | G | W | M | V | E | M | P | K | A | S | M | Y | V | W | A | K | I | P | E | P | Y | . |
. |
A |
Query Conservation |   |
  |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   | . |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   | . | . |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
R | D | G | L | V | K | L | S | Q | R | I | L | G | P | C | T | I | V | Q | G | A | L | K | S | I | L | C | R | T | P | G | E | F | Y | H | N | T | L | S | F | L | K | S | N | A | D | L | C | Y | G | A | L | A | A | I | P | G | L | R | P | V | R | P | S | G | A | M | Y | L | M | V | G | I | E | M | E | H | F | P | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | T | T |  |  |  |
|
|
|
| B | T | T |  |  |  |  |  |  |
| G | G | G |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
306 | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . |
  |
  |   |
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | M | G | S | L | E | F | A | K | K | L | L | N | E | A | K | V | C | V | S | P | G | I | G | F | G | D | Y | G | D | T | H | V | R | F | A | L | I | E | N | R | D | R | I | R | Q | A | I | R | G | I | K | A | M | F | R | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |
|   |
|   |   |   |
|   |
|
|   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |
|   |
|
|   |   |
|   | . | . |   |   |   |   |
|
|
|
|   |   |   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |   |   |   |   |
Template Sequence |   |
F | E | N | D | V | E | F | T | E | R | L | V | A | E | Q | S | V | H | C | L | P | A | T | C | F | E | . |
. |
Y | P | N | F | I | R | V | V | I | T | V | P | E | V | M | M | L | E | A | C | S | R | I | Q | E | F | C | E | Q |
Template Known Secondary structure |   |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|  |  | G | G | G | G | T | . | . |
| T | T |  |  |  |  |  | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
386 | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | |
|
. | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 |
  |