|   |
49 | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | T | P | P | H | I | V | E | K | L | C | T | V | A | Q | R | P | D | T | H | G | Y | S | T | S | R | G | I | P | R | L | R | R | A | I | S | R | W | Y | Q | D | R | Y | D | V | E | I | D | P | E | S | E | A | I | V | T | I | G | S | K | E | G | L | A | H | L | M | L | A | T | L | D | H | G | D | T | V | L | V | P |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|
|
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   | . |   |
|
|   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
Template Sequence |   |
K | V | R | L | E | Q | L | Q | T | L | T | T | T | A | A | A | L | F | G | T | S | H | R | Q | A | P | . |
V | K | N | L | V | G | R | V | R | S | G | L | A | E | L | F | S | L | P | D | G | Y | . |
E | V | I | L | G | N | G | G | A | T | A | F | W | D | A | A | A | F | G | L | I | D | K | R | S | L | H | L | T | Y |
Template Known Secondary structure |   |
|
|
|  |  |  |  | G | G | G | G | T | T | T | G | G | G | T | T | S |
| T | T | S |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T |
| . |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
|  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
28 | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
. | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . |
  |
  |   |
129 | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | P | S | Y | P | I | H | I | Y | G | A | V | I | A | G | A | Q | V | R | S | V | P | L | V | E | G | V | D | F | F | N | E | L | E | R | A | I | R | E | S | Y | P | K | P | K | M | M | I | L | G | F | P | S | N | P | T | A | Q | C | V | E | L | E | F | F | E | K | V | V | A | L | A | K | R | Y | D | V | L | V | V |
Query Conservation |   |
  |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | E | F | S | A | K | F | A | S | A | V | S | K | N | P | F | V | G | E | P | I | I | I | T | S | D | P | G | S | A | P | . |
. |
. |
. |
. |
E | P | Q | T | D | P | S | V | D | V | I | A | W | A | H | N | E | T | S | T | G | V | A | V | A | V | R | R | . |
. |
. |
. |
. |
. |
. |
P | E | G | S | D | A | L | V | V |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|
|
|  |  |  |  |
|
| T | T |
|
|
| . | . | . | . | . |
|
|
|
|
| T | T |
| S |  |  |  |  |  | S |  |  | T | T | T | T |  |  |
|
|
|
|
| . | . | . | . | . | . | . |
| T | T |
|
|
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|  |  | . | . | . | . | . | . | . |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
106 | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | 170 | . | . | . |
  |
  |   |
209 | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
H | D | L | A | Y | A | D | I | V | Y | D | G | W | K | A | P | S | I | M | Q | V | P | G | A | R | D | V | A | V | E | F | F | T | L | S | K | S | Y | N | M | A | G | W | R | I | G | F | M | V | G | N | K | T | L | V | S | A | L | A | R | I | K | S | Y | H | D | Y | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | D | A | T | S | G | A | G | G | L | P | V | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | A | E | T | D | A | Y | Y | F | A | P | Q | K | N | F | A | S | D | G | . |
G | L | W | L | A | I | M | S | P | A | A | L | S | R | I | E | A | I | A | A | T | G | R | W | V | P | D | F | L | S | L | P | I | A | V | E | N |
Template Known Secondary structure |   |
 |  |
| T | T | T | T | T | T | S |
|
|
| . | . | . | . | . | . | . | . | . | . | G | G | G |
| S |  |  |  |  |
| T | T | S | T | T |
| S |
| S | . | S |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| G | G | G |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
175 | . | . | . | . | 180 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
277 | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
. | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | F | T | P | L | Q | V | A | A | I | A | A | L | E | . |
. |
G | D | Q | Q | C | V | R | D | I | A | E | Q | Y | K | R | R | R | D | V | L | V | K | G | L | H | E | A | G | W | M | V | E | M | P | K | . |
. |
. |
. |
. |
A | S | M | Y | V | W | A | K | I | P | E | P | Y | A | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   | . | . | . | . | . |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |
Template Sequence |   |
S | L | K | N | Q | T | Y | N | T | P | A | I | A | T | L | A | L | L | A | E | Q | I | D | W | L | V | G | N | G | G | L | D | W | A | V | K | R | T | A | D | S | S | Q | R | L | Y | S | W | A | Q | E | R | P | Y | T | T | P | F | V | T | D | P | G | L | R | S | Q | V | V | G | T | I | D | F | V | D | . |
. |
. |
D |
Template Known Secondary structure |   |
 | T | T | T |
|
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |  |  |  | S |
|
| S | G | G | G | B |
| S | S |  |  |  |  |  |  |
| T | . | . | . | T |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
| . | . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | |
|
|
320 |
  |
  |   |
341 | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | |
|
. | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | G | S | L | E | F | A | K | K | L | L | N | E | A | K | V | C | V | S | P | G | I | G | F | G | D | Y | G | D | T | H | V | R | F | A | L | I | . |
. |
E | N | R | D | R | I | R | Q | A | I | R | G | I | K | A | M | F | R | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   | . | . |   |   |   |
|   |
|   |   |   |
|   |
|
|   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |
| . |   |   |   |
|
|   |
|   |   |
| . | . |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |
|   |
|
|
|   |   |
|   |   |   |
|   |
|   |   |   |   |
Template Sequence |   |
V | D | A | G | T | V | A | K | I | L | . |
R | A | N | G | I | V | D | T | E | P | . |
. |
Y | R | K | L | G | R | N | Q | L | R | V | A | M | F | P | A | V | E | P | D | D | V | S | A | L | T | E | C | V | D | W | V | V | E | R |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  | . |  |  | T | T |
| B |
|
| S |
| . | . |
| T | T | T |
|
| S |  |  |  |  |  |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  | . |  |  |
|
|
|  |  |  |  |
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
321 | . | . | . | . | . | . | . | . | 330 | |
. | . | . | . | . | . | . | . | . | 340 | |
|
. | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . |
  |