|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | |
. | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |
|
|  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | P | V | T | L | S | E | P | H | F | S | Q | H | T | L | N | K | Y | A | S | L | M | A | Q | G | N | G | Y | L | G | L | R | A | S | H | E | E | D | Y | T | R | Q | T | . |
R | G | M | Y | L | A | G | L | Y | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | A | G | K | G | E | I | N | E | L | V | N | L | P | D | V |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
|
|   |
|
|
|
|
|   |   |
|
|   |   |   |   |   |   | . |   |   |
|   |   |   |
|   |
|   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
Q | P | W | N | V | I | T | H | T | F | D | P | K | D | K | R | L | Q | E | S | M | T | S | L | G | N | G | Y | M | G | M | R | G | D | F | E | E | G | Y | S | G | D | S | L | Q | G | I | Y | L | G | G | V | W | Y | P | D | K | T | R | V | G | W | W | K | N | G | Y | P | K | Y | F | G | K | V | V | N | A | V | N | F |
Template Known Secondary structure |   |
| S | S |  |  |  |  | S |
|
|
| G | G | G |  |  |  |  |  |  |  | T |
|  |  |
| S | S |  |  |  |
|
|
|
| T | T |
|
|
| S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| S | S |
|
| T | T |
|
| S |  |  |  |  |  |  |  |
|
| B |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . |
  |
  |   |
72 | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | |
|
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | |
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Query Sequence |   |
V | G | M | E | I | A | I | N | G | E | V | F | S | L | S | H | . |
. |
. |
E | A | W | Q | R | E | L | D | F | A | S | G | E | L | R | R | N | V | V | W | R | T | S | N | G | S | G | Y | T | I | A | S | R | R | F | V | S | A | D | Q | L | P | L | I | A | L | E | I | T | I | T | P | L | . |
D | A | D | A | S | V | L |
Query Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . |
|   |
|   |
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |
|   |
|   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |   | . |
|   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
I | K | L | P | I | E | I | N | G | E | P | V | D | L | A | K | D | K | I | S | D | F | T | L | D | L | D | M | H | Q | G | V | L | N | R | S | F | V | V | E | R | . |
G | A | V | R | V | A | L | N | F | Q | R | F | L | S | V | A | Q | P | E | L | S | V | Q | K | V | T | V | K | N | L | S | D | A | E | V | D | V | T |
Template Known Secondary structure |   |
|
|
|
|  |  |  | T | T |  |  |
|
| T | T | T | S |  |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |  | . | T | T |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S | T | T |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
88 | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | |
. | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . |
  |
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | |
|
|
. | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | S | T | G | I | D | A | T | Q | T | N | H | G | R | Q | H | . |
. |
. |
L | D | E | T | Q | V | R | V | F | G | Q | H | L | M | Q | G | S | Y | T | T | Q | D | G | . |
. |
. |
. |
. |
R | S | D | V | A | I | S | C | C | C | K | V | S | G | D | V | Q | Q | C | Y | T | A | K | E | R | R | L | L | Q | H | T | S | A |
Query Conservation |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | K | P | S | I | D | A | D | V | M | N | E | E | A | N | Y | D | E | R | F | W | D | V | L | A | T | D | Q | Q | A | D | R | G | S | I | V | A | K | T | T | P | N | P | F | G | T | P | R | F | T | S | G | M | E | M | R | L | V | T | D | L | K | N | V | A | I | T | Q | P | N | E | K | E | V | T | T | A | Y | T | G |
Template Known Secondary structure |   |
 |
|
|  |  |  |
|
|
|
|
| T | T |
| T | T | S |
|
|
|  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |
|
|
| S | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | S | S |  |  |  |
|
|
|
|
| B | T | T |  |  |  |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
167 | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . |
  |
  |   |
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | L | H | A | G | E | T | M | T | L | Q | K | L | V | W | I | D | W | R | D | D | R | Q | A | A | L | D | E | W | G | S | A | S | L | R | Q | L | E | M | C | A | Q | Q | S | Y | D | Q | L | L | A | A | S | T | E | N | W | R | Q | W | W | Q | K | R | R | I | T | V | N | G | G | E | A | H | D | Q | Q | A | L | D | Y |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |
|   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|   |
|   |   | . |
|   |   |
|
|   |   |   |   |   |
Template Sequence |   |
K | L | A | P | Q | A | S | A | E | L | E | K | R | V | I | V | V | T | S | R | D | Y | D | T | Q | . |
E | S | L | T | A | A | M | H | Q | L | S | D | K | V | A | Q | S | S | Y | E | D | L | L | N | A | H | T | A | I | W | A | Q | R | W | E | K | S | D | V | V | I | K | G | . |
D | D | E | S | Q | Q | G | I | R | F |
Template Known Secondary structure |   |
 |  |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S | S |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  | S | . |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
. | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
. | . | . | . | . | 320 | . | . | . | . |
  |
  |   |
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
. | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | Y | H | L | R | I | M | T | P | A | H | D | E | R | S | S | I | A | A | K | G | L | T | G | E | G | Y | K | G | H | V | F | W | D | T | E | V | F | L | L | P | F | H | L | F | . |
S | D | P | T | V | A | R | S | L | L | R | Y | R | W | H | N | L | P | G | A | Q | E | K | A | R | R | N | G | W | Q | G | A | L |
Query Conservation |   |
  |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |
|
|   |
|
|
|   |
|
|   |   |   |
|   |   |   |   | . |   |   |
|
|   |
|   |   |
|
|   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|
|   |
Template Sequence |   |
N | L | F | Q | L | F | S | T | Y | Y | G | E | D | A | R | L | N | I | G | P | K | G | F | T | G | E | K | Y | G | G | A | T | Y | W | D | T | E | A | F | A | F | P | V | Y | L | G | I | T | D | P | K | V | T | R | N | L | L | M | Y | R | Y | K | Q | L | D | G | A | Y | I | N | A | Q | E | Q | G | L | K | G | A | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
|
| S | S |
| T | T |
|
|
|
| T | T | T | T | S |
| S | T | T | T | T |
| B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
325 | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . |
  |
  |   |
379 | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | P | W | E | S | A | R | S | G | E | E | E | T | P | E | F | A | A | I | N | I | R | T | G | L | R | Q | K | V | A | S | A | Q | A | E | H | H | L | V | A | D | I | A | W | A | V | I | Q | Y | W | Q | T | T | G | D | E | S | F | I | A | H | E | G | M | A | L | L | L | E | T | A | K | F | W | I | S | R | A | V | R |
Query Conservation |   |
|
|
|   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |
|
|   |   |
|   |
|   |   |
|
|   |   |   |   |   |
|   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   | . |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|
|   |   |   |   |   |
|   |
|   |
|   |
|   |
|   |   |   |   |
|   |   |
Template Sequence |   |
F | P | M | V | T | F | . |
D | G | I | E | C | H | N | E | W | E | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | F | E | E | I | H | R | N | G | D | I | A | F | A | I | Y | N | Y | T | R | Y | T | G | D | D | S | Y | V | L | H | E | G | A | K | V | L | T | E | I | S | R | F | W | A | D | R | V | H | F |
Template Known Secondary structure |   |
|
| S | S | B | S | . | S | S | S |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  | T | T |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
Template Predicted Secondary structure |   |
 |
|  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
405 | . | . | . | . | 410 | |
. | . | . | . | . | . | . | . | . | 420 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 |
  |
  |   |
459 | |
|
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | . |
. |
N | D | R | L | E | I | H | D | V | I | G | P | D | E | Y | T | E | H | V | N | N | N | A | Y | T | S | Y | M | A | R | Y | N | V | Q | Q | A | L | N | . |
. |
. |
. |
. |
. |
. |
. |
I | A | R | Q | F | G | C | S | D | D | A | F | I | H | R | A | E | M | F | L | K | E | L | W | M | P | E | I | Q | P | D |
Query Conservation |   |
  | . | . |   |   |   |
|   |
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
S | K | R | N | N | Q | Y | M | I | H | G | V | T | G | A | D | E | Y | E | N | N | V | D | N | N | W | D | T | N | M | L | A | Q | W | T | L | K | Y | T | L | E | I | L | G | K | V | D | Q | D | T | A | K | Q | L | D | V | . |
S | D | E | E | K | T | K | W | Q | D | I | V | D | R | M | Y | L | P | Y | D | K | D | L |
Template Known Secondary structure |   |
 | T | T | T | T |  |  |  |
|
| S | B |
|
| S |
| T | T | S |
| S | B | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  | T |
| . |
|  |  |  |  |  |  |  |  |  |  |  |  | T | B |
|
|
|  |  | T | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
471 | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | |
. | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . |
  |
  |   |
529 | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | L | P | Q | D | D | S | F | M | A | K | P | A | I | N | L | A | K | Y | K | A | A | A | G | K | Q | T | I | L | L | D | Y | S | R | A | E | V | N | E | M | Q | I | L | K | Q | A | D | V | V | M | L | N | Y | M | L | P | E | Q | F | S | A | A | S | C | L | A | N | L | Q | F | Y | E | P | R | T | I | H | D | S |
Query Conservation |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|
Template Sequence |   |
N | I | F | V | Q | H | D | G | F | L | D | K | D | I | E | P | V | S | S | I | P | A | D | Q | R | P | I | N | Q | N | W | S | W | D | K | I | L | . |
. |
R | S | P | Y | I | K | Q | G | D | V | L | Q | G | I | W | D | F | I | D | D | Y | T | P | E | Q | K | K | A | N | F | D | F | Y | E | P | L | T | V | H | E | S |
Template Known Secondary structure |   |
T |  |  |
| S | S | T | T | G | G | G | S |
|
|
|
| G | G | G | S |
| G | G | G |
| S |  |  |  |  | S |
|  |  |  |  |  | . | . |  | S | S |
| B | S | S |
| S |  |  |  |  |  |  |  | T | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  | G | G | G | B |
|
|
| S |
Template Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | |
|
. | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . |
  |
  |   |
609 | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | L | S | K | A | I | H | G | I | V | A | A | R | C | G | L | L | T | Q | S | Y | Q | F | W | R | E | G | T | E | I | D | L | G | A | D | P | H | S | C | D | D | G | I | H | A | A | A | T | G | A | I | W | L | G | A | I | Q | G | F | A | G | V | S | V | R | D | G | E | L | H | L | N | P | A | L | P | E | Q | W | Q |
Query Conservation |   |
|   |
|   |   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|
|   |
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |
|
|   |
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |
|
|
|
|   |   |
|   |
Template Sequence |   |
S | L | S | P | A | I | H | S | V | L | A | A | D | L | H | Y | E | D | K | A | V | E | L | Y | S | R | T | A | R | L | D | L | D | N | Y | N | N | D | T | T | D | G | L | H | I | T | S | M | T | G | A | W | I | A | V | V | Q | G | F | A | G | M | R | V | R | D | G | Q | L | H | Y | A | P | F | L | P | K | T | W | T |
Template Known Secondary structure |   |
T | T | S |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T | T | T | T | S |
| G | G | G |
|
|
| G | G | G | G | G |  |  |  |  |  |  |  | T | T | T | T |
|
|  |  |  | T | T |  |  |  |  |
|
|
|
|
| T | T |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
628 | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . |
  |
  |   |
689 | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | |
|
. | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | L | S | F | P | L | F | W | Q | G | C | E | L | Q | V | T | L | D | A | Q | R | I | A | I | R | . |
. |
T | S | A | P | V | S | L | R | L | N | G | Q | L | I | T | V | A | E | E |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
S | Y | T | F | R | Q | V | F | R | D | R | L | I | E | V | S | V | H | A | D | G | P | H | F | K | L | L | S | G | E | P | L | T | I | D | V | A | G | A | A | A | A | A | A | A | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  | T | T |  |  |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
708 | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . |
  |