|   |
587 | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | |
. | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | |
|
|
. | . | . | . | . | . | . | . | . | 660 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |  |  |  |  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | E | Q | Y | Q | L | F | C | D | S | F | P | F | E | . |
T | T | P | D | Q | A | Q | A | I | N | A | V | L | S | D | M | C | Q | P | L | A | M | D | R | L | V | C | G | D | V | G | F | G | K | T | E | V | A | M | R | A | A | F | L | A | V | D | N | H | K | . |
. |
. |
Q | V | A | V | L | V | P | T | T | L | L | A |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |   | . |   |
|   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |
|
|
|
|
|   |
|
|
|
|   |
|
|
|
|
|
|   |   |
|
|   |   |
|   |   |   |
|
| . | . | . |
|
|   |
|
|
|
|
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |
|   | . | . | . | . |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |
Template Sequence |   |
K | P | Q | L | L | Q | G | V | Y | A | M | G | F | N | R | P | S | K | I | Q | E | N | A | L | P | L | M | L | A | E | P | P | Q | . |
. |
. |
. |
N | L | I | A | Q | S | Q | S | G | T | G | K | T | A | A | F | V | L | A | M | L | S | Q | V | E | P | A | N | K | Y | P | Q | C | L | C | L | S | P | T | Y | E | L | A |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  | S | S | S |
|
| . | . | . | . |
|  |  |  |  |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T | S |
| S |
|
|  |  |  |  |
| S | S |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | |
|
|
|
. | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . |
  |
  |   |
663 | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | |
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
Q | Q | H | Y | D | N | F | R | D | R | F | A | N | W | P | V | R | I | E | M | I | S | R | F | R | S | A | K | E | Q | T | Q | I | L | A | E | V | A | E | G | K | I | D | I | L | I | G | T | H | K | L | L | Q | S | . |
. |
. |
. |
. |
. |
D | V | K | F | K | D | L | G | L | L | I | V | D | E | E | H | . |
. |
. |
. |
Query Conservation |   |
  |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |   |
|
|   |   | . | . | . | . | . | . |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | Q | T | G | K | V | I | E | Q | M | G | K | F | Y | P | E | L | K | L | A | Y | A | V | R | G | N | K | . |
. |
. |
. |
. |
. |
L | E | R | G | Q | K | I | S | E | Q | I | V | I | G | T | P | G | T | V | L | D | W | C | S | K | L | K | F | I | D | P | K | K | I | K | V | F | V | L | D | E | A | D | V | M | I | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T | T | S | T | T |
|
|  |  |  |  |
| T | T |
|
| . | . | . | . | . | . |
|
| T | T |
|
|
|
|
| S |  |  |  |  |
|  |  |  |  |  |  |  |  | T | T | S |
| S | S |
| G | G | G |
|
|  |  |  |  |  | T |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
176 | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
733 | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
R | F | G | V | R | H | K | E | R | I | K | A | M | R | A | N | V | D | I | L | T | L | T | A | T | P | I | P | R | T | L | N | M | A | M | S | G | M | R | D | L | S | I | I | A | T | P | P | A | R | R | L | A | V | . |
. |
. |
. |
. |
K | T | F | V | R | E | Y | D | S | M | V | V | R | E | A | I | L | R | E |
Query Conservation |   |
. | . |
|
|
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |
|   |   |
|   |
|   |
|   |   |   |
|   |   |
|   |   |
| . | . | . | . | . |   |
|   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | Q | G | H | Q | D | Q | S | I | R | I | Q | R | M | L | P | R | N | C | Q | M | L | L | F | S | A | T | F | E | D | S | V | W | K | F | A | Q | K | V | V | P | D | P | N | V | I | K | L | K | R | E | E | E | T | L | D | T | I | K | Q | Y | Y | V | L | C | S | S | R | D | E | K | F | Q | A | L | C | N | L | Y | G |
Template Known Secondary structure |   |
T | T | T | T |  |  |  |  |  |  |  |  |  | T | S |
| T | T |
|  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  | S | S | S |
|  |  |  |
|
|
| G | G | G | S | S |
| T | T |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . |
  |
  |   |
806 | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | L | R | G | G | Q | V | Y | Y | L | Y | N | D | V | E | N | I | Q | K | A | A | E | R | L | A | E | L | V | P | E | A | R | I | A | I | G | H | G | Q | M | R | E | R | E | L | E | R | V | M | N | D | F | H | H | Q | R | F | N | V | L | V | C | T | T | I | I | E | T | G | I | D | I | P | T | A | N | T | I | I | I |
Query Conservation |   |
|   |
|
|
|
|
|   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |   |
|
|
|
|   |
|
|
|
|
|   |
|
|
|
|
|   |   |
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|
|   |
Template Sequence |   |
A | I | T | I | A | Q | A | M | I | F | C | H | T | R | K | T | A | S | W | L | A | A | E | L | S | K | E | . |
. |
G | H | Q | V | A | L | L | S | G | E | M | M | V | E | Q | R | A | A | V | I | E | R | F | R | E | G | K | E | K | V | L | V | T | T | N | V | C | A | R | G | I | D | V | E | Q | V | S | V | V | I | N |
Template Known Secondary structure |   |
 |  | S | S | S |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | T |
|
|
|  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  |
| G | G | G | T | S | S |
|
|
| T | T |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | |
|
. | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . |
  |
  |   |
886 | . | . | . | 890 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | R | A | D | H | . |
. |
. |
. |
. |
F | G | L | A | Q | L | H | Q | L | R | G | R | V | G | R | S | H | H | Q | A | Y | A | W | L | L | T | P | H | P | K | A | M | T | T | D | A | Q | K | R | L | E | A | I | A | S | L |
Query Conservation |   |
  |   |
|
|   | . | . | . | . | . |   |
|
|
|   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|   |   |
|   |   |   |   |
|   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
F | D | L | P | V | D | K | D | G | N | P | D | N | E | T | Y | L | H | R | I | G | R | T | G | R | F | G | K | R | G | L | A | V | N | M | V | D | S | . |
. |
. |
. |
. |
K | H | S | M | N | I | L | N | R | I | Q | E | H |
Template Known Secondary structure |   |
S | S |
|
| B |
| S | S | S | S | B |
|  |  |  |  |  |  |  |  | T | T | S | S |
| T | T |
|
|  |  |  |  |  |  |  |
| S | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
408 | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 450 | . | . | . | . | . | . | . | . |
  |