|   |
616 | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | |
. | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | C | Q | P | L | A | M | D | R | L | V | C | G | D | V | G | F | G | K | T | E | V | A | M | R | . |
A | A | F | L | A | V | D | N | H | K | Q | V | A | V | L | V | P | T | T | L | L | A | Q | Q | H | Y | D | N | F | R | D | R | F | A | N | W | P | V | R | I | E | M | I | S | R | F | R | S | A | K | E | Q | T | Q |
Query Conservation |   |
  |   |   |   |   |   |
|
|
|
|
|   |
|
|
|
|   |
|
|
|
|
|
|   |   | . |
|
|   |   |
|   |   |   |
|
|
|
|   |
|
|
|
|
|   |   |
|
|   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |
|   | . | . |   |   |
|
|   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
L | K | K | G | X | . |
. |
T | T | V | L | D | F | H | P | G | A | G | K | T | R | R | F | L | P | Q | I | L | A | E | C | A | R | R | R | L | R | T | L | V | L | A | P | T | R | V | V | L | S | E | X | K | E | A | F | H | G | L | D | V | K | F | H | T | Q | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T | S | T | T |
| . | . |  |  |  |  |
|
|
| T | T | S |
| T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |
| S | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
| . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
188 | . | 190 | . | . | |
|
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
695 | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | |
|
|
|
. | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | L | A | E | V | A | E | G | K | I | D | I | L | I | G | T | H | K | L | L | Q | S | . |
. |
. |
. |
D | V | K | F | K | D | L | G | L | L | I | V | D | E | E | H | R | F | G | V | R | H | K | E | R | I | K | A | M | R | A | . |
. |
. |
. |
. |
N | V | D | I | L | T | L | T | A | T | P | I | P | R | T | L | N | M |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |   |
|
|   |   | . | . | . | . |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |   |   | . | . |
Template Sequence |   |
. |
F | S | A | H | G | S | G | R | E | V | I | D | A | X | C | H | A | T | L | T | Y | R | X | L | E | P | T | R | V | V | N | W | E | V | I | I | X | D | E | A | H | F | L | D | P | A | S | I | A | A | R | G | W | A | A | H | R | A | R | A | N | E | S | A | T | I | L | X | T | A | T | P | P | G | T | S | D | . |
. |
Template Known Secondary structure |   |
. |
|
|
|
|
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
|
|
|
|
| S |  |  |  |  | T | T | T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |
| S | S |
| T | T |
|
|
| . | . |
Template Predicted Secondary structure |   |
. |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | |
|
  |
  |   |
766 | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | M | S | G | M | R | D | L | S | I | I | A | T | P | P | A | R | R | L | A | V | K | T | F | V | R | E | Y | D | S | M | V | V | R | E | A | I | L | R | E | I | L | R | G | G | Q | V | Y | Y | L | Y | N | D | V | E | N | I | Q | K | A | A | E | R | L | A | E | L | V | P | E | A | R | I | A | I | G | H | G | Q | M |
Query Conservation |   |
|
|   |
|   |   |
|   |
|   |
|   |   |   |
|   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|
|
|
|
|   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   | . | . |
|   |   |
|   |   |
|
|
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | F | P | H | S | N | G | E | I | E | D | V | Q | T | D | I | P | S | E | P | W | N | T | G | H | D | W | I | L | A | D | K | R | P | T | A | W | F | L | P | S | I | R | A | A | N | V | X | A | A | S | L | R | K | A | . |
. |
G | K | S | V | V | V | L | N | R | K | T |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | S | S |
|
|
| S | S |
|  |  |  |  |  |
|
|
|
| S | S |
|
| S | S | S |
| T |  |  |  |  |
|
| S |
|  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | T |
|
|  |  |  |
|
| S | S | S |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
329 | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | |
|
. | . | . | . | . | . | 390 | . | . | . | . |
  |
  |   |
846 | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |
|
|
| . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | E | R | E | L | E | R | V | M | N | D | F | H | H | Q | R | F | N | V | L | V | C | T | T | I | I | E | T | G | I | . |
. |
. |
. |
. |
D | I | P | T | A | N | T | I | I | I | E | R | A | D | H | F | G | L | A | Q | L | H | Q | L | R | G | R | V | G | R | S | H | H | Q | A | Y | A | W | L | L | T | P | H | P | K |
Query Conservation |   |
  |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |   |
|
|
|
|   |
|
|
|
|
|   |
|
| . | . | . | . | . |
|
|
|   |   |
|   |
|
|
|   |   |
|
|   |   |
|
|
|   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
F | E | K | K | P | D | F | I | L | A | T | D | I | A | E | X | G | A | N | L | C | V | E | R | V | L | D | C | R | T | A | F | K | P | V | L | V | D | E | G | R | K | V | A | I | K | G | P | L | R | I | S | A | S | S | A | A | Q | R | R | G | R | I | G | R | N | P | N | R | D | G | D | S | Y | Y | Y | S | E | P | T |
Template Known Secondary structure |   |
|
|
|
|
| S |  |  |  |  | S | S | G | G | G |
|
| T | T |
|
|
| S |  |  |  |  |
|
|  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | T | T | S | S |
|
| T | T |
|
|
|  |  |  |  |  |
| S |
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
395 | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . |
  |
  |   |
921 | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . | . | . | 960 | . | . | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . | . | . | 980 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | M | T | T | D | A | Q | K | R | L | E | A | I | A | S | L | E | D | L | G | A | G | F | A | L | A | T | H | D | L | E | I | R | G | A | G | E | L | L | G | E | E | Q | S | G | S | M | E | T | I | G | F | S | L | Y | M | E | L | L | E | N | A | V | D | A | L |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |
|
|   |   |
|
|   |
|   |   |
|
|   |   |
|   |
|   |
|   |   |
|
|   |
|
|
|   |   |
|
|   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | E | N | N | A | H | H | V | C | W | L | E | A | S | . |
. |
. |
. |
. |
. |
. |
. |
X | L | L | D | N | X | E | V | R | G | G | X | V | A | P | L | Y | G | V | E | G | T | K | T | P | V | S | P | G | E | X | R | L | R | D | D | Q | R | K | V | F | R | E | L |
Template Known Secondary structure |   |
|
|
|
| T | T | B |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  | T | T | S |
|
| G | G | G |
|
|
|
|
| S | T | T |  |  |  |  |
| S | S |
| T | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
483 | . | . | . | . | . | . | 490 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 |
  |