|   |
625 | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | C | G | D | V | G | F | G | K | T | E | V | A | M | R | A | A | F | L | A | V | D | N | H | K | Q | V | A | V | L | V | P | T | T | L | L | A | Q | Q | H | Y | D | N | F | R | D | R | F | A | N | W | P | V | R | I | E | M | I | S | R | F | R | S | A | K | E | Q | T | Q | I | L | A | E | V | A | E | G | K | I |
Query Conservation |   |
|
|   |
|
|
|
|   |
|
|
|
|
|
|   |   |
|
|   |   |
|   |   |   |
|
|
|
|   |
|
|
|
|
|   |   |
|
|   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|   |   |
|
|   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |   |
|
|   |   |   |
|   | . | . | . |   |   |
|   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |
|
Template Sequence |   |
H | L | H | A | P | T | G | S | G | K | S | . |
. |
. |
T | K | V | P | A | A | Y | A | A | Q | G | Y | K | V | L | V | L | N | P | S | V | A | A | T | L | G | F | G | A | Y | M | S | K | A | H | G | I | . |
. |
. |
D | P | N | I | R | T | G | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | T | I | T | T | G | A |
Template Known Secondary structure |   |
 |  |  |
|
| T | T | S |
| T | T | . | . | . | T |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|  |  |  |
| S | S | . | . | . | . | . | . | . | . | . | . | . |
|  |  |
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1201 | . | . | . | . | . | . | . | . | 1210 | . | |
|
|
. | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | |
|
|
. | 1250 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | 1260 | . | . | . |
  |
  |   |
705 | . | . | . | . | 710 | . | . | . | . | |
|
. | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |
|
|  |  |  |  | . | . |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | I | L | I | G | T | H | K | L | L | . |
. |
Q | S | D | V | K | F | K | D | L | G | L | L | I | V | D | E | E | H | . |
. |
. |
. |
. |
. |
R | F | G | V | R | H | K | E | R | I | K | A | M | R | A | N | V | D | I | L | T | L | T | A | T | P | I | P | R | T | L | N | M | A | M | S | G | M | R | D | L | S | I | I |
Query Conservation |   |
|
|
|
|
|
|   |   |
|
| . | . |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |
|   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |   | . | . | . | . |   |   |   |   |
|   |
|   |   |   |
Template Sequence |   |
P | V | T | Y | S | T | Y | G | K | F | L | A | D | G | G | C | S | G | G | A | Y | D | I | I | I | C | D | E | C | H | S | T | D | S | T | T | I | L | G | I | G | T | V | L | D | Q | A | E | T | A | G | A | R | L | V | V | L | A | T | A | T | P | P | G | S | V | . |
. |
. |
. |
T | V | P | H | P | N | I | E | E | V |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| T | T | S |
| S |  |  |  |  | T | T | T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T |
| S |  |  |  |  |  |  | S | S |
| T | T |
|
| . | . | . | . |
|
|
|
| T | T |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1264 | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . | . | 1310 | . | . | . | . | . | . | . | . | . | 1320 | . | . | . | . | . | . | . | . | . | |
|
|
|
1330 | . | . | . | . | . | . | . | . | . |
  |
  |   |
777 | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | T | P | P | A | R | R | L | A | V | K | T | F | V | R | E | Y | D | S | M | V | V | R | E | A | I | L | R | E | I | L | R | G | G | Q | V | Y | Y | L | Y | N | D | V | E | N | I | Q | K | A | A | E | R | L | A | E | L | V | P | E | A | R | I | A | I | G | H | G | Q | M | R | E | R | E | L | E | R | V | M | N | D |
Query Conservation |   |
  |   |   |
|   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|
|
|
|
|   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |   | . | . |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . |
Template Sequence |   |
A | L | S | N | T | G | E | I | P | F | Y | G | K | A | I | P | I | E | A | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | G | G | R | H | L | I | F | C | H | S | K | K | K | C | D | E | L | A | A | K | L | S | G | L | . |
. |
G | I | N | A | V | A | Y | Y | R | G | L | D | V | S | V | I | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |
|
| S |
| S | S |  |  |  | T | T |  |  |  |
| G | G | G | T | . | . | . | . | . | . | . | . | . | . | . | S | S | S |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | T |
|
|  |  |  |  |
| T | T | S |
| G | G | G | S | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
| . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1340 | . | . | . | . | . | . | . | . | . | 1350 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
1360 | . | . | . | . | . | . | . | . | . | 1370 | . | . | . | . | . | . | . | . | . | 1380 | . | . | . | . | |
|
. | . | . | . | . | 1390 | . | . | . | . | . | . | . | . | . | 1400 | |
|
|
|
|
|
  |
  |   |
857 | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | H | H | Q | R | F | N | V | L | V | C | T | T | I | I | E | T | G | I | D | I | P | T | A | N | T | I | I | . |
. |
. |
. |
. |
. |
. |
. |
I | E | R | A | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | F | G | L | A | Q | L | H | Q | L | R | G | R | V | G | R | S | H | H | Q | A | Y | A | W | L | L | T |
Query Conservation |   |
|   |   |
|   |   |
|
|
|
|   |
|
|
|
|
|   |
|
|
|
|
|   |   |
|   |
|
| . | . | . | . | . | . | . | . |
|   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|   |   |
|
|
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|   |
|
|   |
|
|
|
|
| . |   |   |
|
|   |
|
|   |
|   |
Template Sequence |   |
. |
P | T | I | G | D | V | V | V | V | A | T | D | A | L | M | T | G | Y | T | G | . |
D | F | D | S | V | I | D | C | N | T | C | V | T | Q | T | V | D | F | S | L | D | P | T | F | T | I | E | T | T | T | V | P | Q | D | A | V | S | R | S | Q | R | R | G | R | T | G | R | . |
G | R | R | G | I | Y | R | F | V | T |
Template Known Secondary structure |   |
. |
| S | S | S | S |  |  |  |  |  |
| T | T |  |  |  |  |
|
|
| . |
|
| S |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
| S | S | S |
|  |  |  |  |  |  |  |  |
| B |  |  |  |  |  |  |  |  | T | T | S |
| S | . | S | S |
|  |  |  |  |  | S |
|
Template Predicted Secondary structure |   |
. |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
1401 | . | . | . | . | . | . | . | . | 1410 | . | . | . | . | . | . | . | . | . | 1420 | |
. | . | . | . | . | . | . | . | . | 1430 | . | . | . | . | . | . | . | . | . | 1440 | . | . | . | . | . | . | . | . | . | 1450 | . | . | . | . | . | . | . | . | . | 1460 | . | . | . | . | . | . | . | |
. | . | 1470 | . | . | . | . | . | . | . |
  |
  |   |
917 | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | H | P | K | A | M | T | T | D | A | Q | K | R | L | E | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | G | E | R | P | S | G | M | F | D | S | S | V | L | C | E |
Template Known Secondary structure |   |
|
|
| B |
|
| S | B |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1478 | . | 1480 | . | . | . | . | . | . | . | . | . | 1490 | . | . | . |
  |