|   |
18 | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | |
|
. | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | S | V | A | L | I | L | A | G | G | R | G | T | R | L | K | D | L | T | N | K | R | A | K | P | A | V | H | F | G | G | K | F | R | I | I | D | F | A | L | S | N | C | I | N | S | G | I | R | R | M | G | V | I | T | Q | Y | Q | S | . |
. |
H | T | L | V | Q | H | I | Q | R | G | W | S | F | F | N | E | E | M |
Query Conservation |   |
|
|   |   |
|
|
|
|
|
|
|   |
|
|
|
|   |
|
|
|   |   |   |
|
|   |
|
|
|
|   |
|
|   |
|
|
|   |   |   |
|   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |   |   |   |   | . | . |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   | . |
|
|
|
|
|   |
|   |
|
|
|
|   | . | . | . |   |   |   |
|
|   |
|   |   |
|   |
|   | . |
|
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
M | N | V | . |
A | I | L | L | A | A | G | K | G | E | R | M | S | . |
. |
. |
E | N | V | P | K | Q | F | L | E | I | E | G | R | . |
M | L | F | E | Y | P | L | S | T | F | L | K | S | E | A | I | D | G | V | V | I | V | T | R | R | E | W | F | E | V | V | E | K | R | V | F | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|  |  | . |  |  |  |  |  |
|
|
|
| G | G | G |
| . | . | . |
| S | S |
| G | G | G |
|  |  | T | T |  | . |  | T | T |  |  |  |  |  |  |  |  |  |
| T | T |
| S |  |  |  |  |  |  |
| G | G | G |  |  |  |  |  | T | T |
|
|
| . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  | . |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | |
. | . | . | . | . | . | 10 | . | . | . | . | . | . | |
|
|
. | . | . | 20 | . | . | . | . | . | . | . | . | . | |
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
  |
  |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | |
|
. | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  | . | . |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | E | F | V | D | L | L | P | A | Q | Q | R | M | K | G | E | N | W | Y | R | G | T | A | D | A | V | T | Q | N | L | D | I | I | R | R | Y | K | A | E | Y | V | V | I | L | A | G | D | H | . |
. |
I | Y | K | Q | D | Y | S | R | M | L | I | D | H | V | E | K | G | A | R | C | T | V | A | C | M | P | V | P | I | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |
|
|   | . | . |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | K | V | L | G | I | V | E | G | G | D | T | R | S | Q | S | V | R | S | A | L | E | F | L | E | K | F | S | P | S | Y | V | L | V | H | D | S | A | R | P | F | L | R | K | K | H | V | S | E | V | L | R | R | A | R | E | T | G | A | A | T | L | A | L | K | N | S | D | A | L | V |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | T | T |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|
| S |  |  |  |  |  |  | T | T | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |  |  |  |  |  |
|
| S |
|  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
67 | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . |
  |
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | S | A | F | G | V | M | A | V | D | E | N | D | K | I | I | E | F | V | E | K | P | A | N | P | P | S | M | P | N | D | P | S | K | S | L | A | S | M | G | I | Y | V | F | D | A | D | Y | L | Y | E | L | L | E | E | D | D | R | D | E | N | S | S | H | D | F | G | K | D | L | I | P | K | I | T | E | A | G | L |
Query Conservation |   |
  |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
R | V | E | N | D | R | I | E | Y | I | P | R | K | G | V | Y | R | I | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | P | Q | A | F | S | Y | E | I | L | K | K | A | H | E | N | G | G | E | W | A | D | D | T | E | P | V | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  | T | T |  |  |  |  |  |
|
| T | T |
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| S | S | S |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
138 | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
254 | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Y | A | H | P | F | P | L | S | C | V | Q | S | D | P | D | A | E | P | Y | W | R | D | V | G | T | L | E | A | Y | W | K | A | N | L | D | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |
|
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |
|
|   |
|
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
K | L | G | V | K | I | A | L | V | E | G | D | P | L | C | F | K | V | T | F | K | E | D | L | E | L | A | R | I | I | A |
Template Known Secondary structure |   |
. | . | . | . | . | . | T | T | T |
|
|
|  |  |  |  |
|
| G | G | G |
|
|
|
| S | T | T |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . |
  |