|   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | L | W | G | L | P | V | A | A | L | I | I | I | F | W | L | S | L | F | C | Y | S | A | I | P | V | S | G | A | D | A | T | R | A | L | L | P | G | H | T | P | T | L | P | E | A | L | V | Q | N | L | R | L | P | R | S | L | V | A | V | L | I | G | A | S | L | A | L | A | G | T | L | L | Q | T | L | T | H | N |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|   |
|   |
|   |
|   |
|   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|   |
|   |
|   |
|   |
|   |   |
|   |   |
|
|   |
|   |
|   |
|   |
|
|
Template Sequence |   |
Y | P | K | I | L | F | G | L | T | L | L | L | V | I | T | A | V | I | S | L | G | I | G | R | Y | S | L | S | V | P | Q | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
D | P | V | Q | Q | Q | V | I | F | Q | V | R | L | P | R | I | L | T | A | L | C | V | G | A | G | L | A | L | S | G | V | V | L | Q | G | I | F | R | N |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | T | T |
|
| S | S |
|
|
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
| . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . |
  |
  |   |
88 | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | M | A | S | P | S | L | L | G | I | N | S | G | A | A | L | A | M | A | L | T | S | A | L | S | P | T | P | I | A | G | Y | S | L | S | F | I | A | A | C | G | G | G | V | S | W | L | L | V | M | T | A | G | G | G | F | R | H | T | H | D | R | N | K | L | I | L | A | G | I | A | L | S | A | F | C | M | G | L | T |
Query Conservation |   |
|
|
|   |
|   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |
|   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |
|
|
|   |
|
|
|
|   |   |   |   |   |
|
|   |
Template Sequence |   |
P | L | V | N | P | H | I | I | G | V | T | S | G | S | A | F | G | G | T | L | A | I | F | F | G | F | S | L | Y | . |
. |
. |
G | L | F | T | S | T | I | L | F | G | F | G | T | L | A | L | V | F | L | F | S | . |
. |
. |
. |
. |
F | K | S | L | L | M | L | I | L | I | G | M | I | L | S | G | L | F | S | A | L | V |
Template Known Secondary structure |   |
T | T |
|
| T | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
|
|
. | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
168 | . | 170 | . | . | . | . | . | |
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | I | T | L | L | L | A | E | . |
. |
D | H | A | Y | G | I | F | Y | W | L | A | G | G | V | S | H | A | R | W | Q | D | V | W | Q | L | L | P | V | V | V | T | A | V | P | V | V | L | L | L | A | N | Q | L | N | L | L | N | L | S | D | S | T | A | H | T | L | G | V | N | L | T | R | L | R | L | V | I | N | M | L |
Query Conservation |   |
  |
|
|   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|   |   |   |
|   |
|
|
|
|
|
|   |   |   |
|   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
S | L | L | Q | Y | I | S | D | T | E | E | K | L | P | S | I | V | F | W | L | M | G | S | F | A | T | S | N | W | E | K | L | L | F | F | F | V | P | F | L | L | C | S | S | I | L | L | S | L | S | W | R | L | N | L | L | S | L | D | E | K | E | A | K | A | L | G | V | K | M | A | P | L | R | W | L | V | I | F | L |
Template Known Secondary structure |   |
 |  |  |  |  | S | S |
| T | T | T |  |  |  |  |  |  |  |  | T | T |
|
| S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | G | G | G | G | G | G | S |
|  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
166 | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . |
  |
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | L | L | V | G | A | C | V | S | V | A | G | P | V | A | F | I | G | L | L | V | P | H | L | A | R | F | W | A | G | F | D | Q | R | N | V | L | P | V | S | M | L | L | G | A | T | L | M | L | L | A | D | V | L | A | R | A | L | A | F | P | G | D | L | P | A | G | A | V | L | A | L | I | G | S | P | C | F | V |
Query Conservation |   |
  |   |
|
|   |
|   |   |
|
|   |
|
|   |
|   |
|
|
|
|
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|   |
|
|   |   |
|
|   |
|   |
|   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|   |
|
|
|   |
|
|   |
|   |
|
|
|
|
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|   |
|
|
|   |   |
|   |
|   |
|   |
| . |   |   |   |   |
|
|
|
|   |
|   |   |   |
|
|   |
|   |
|
|
Template Sequence |   |
S | G | S | L | V | A | C | Q | V | A | I | S | G | S | I | G | W | V | G | L | I | I | P | H | L | S | R | M | L | V | G | A | N | H | Q | S | L | L | P | C | T | M | L | V | G | A | T | Y | M | L | L | V | D | N | V | A | R | S | L | . |
S | D | A | E | I | P | I | S | I | L | T | A | L | I | G | A | P | L | F | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | . |
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | |
. | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . |
  |
  |   |
326 | . | . | . | 330 |
Predicted Secondary structure |   |
 |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
Query Sequence |   |
W | L | V | R | R |
Query Conservation |   |
  |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|
Template Sequence |   |
V | L | V | Y | K |
Template Known Secondary structure |   |
 |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
  |   |
325 | . | . | . | . |
  |