Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	A	I	K	H	P	V	L	L	W	G	L	P	V	A	A	L	I	I	I	F	W	L	S	L	F	C	Y	S	A	I	P	V	S	G	A	D	A	T	R	A	L	L	P	G	H	T	P	T	L	P	E	A	L	V	Q	N	L	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																						?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	P	R	S	L	V	A	V	L	I	G	A	S	L	A	L	A	G	T	L	L	Q	T	L	T	H	N	P	M	A	S	P	S	L	L	G	I	N	S	G	A	A	L	A	M	A	L	T	S	A	L	S	P	T	P	I	A	G	Y	S
Secondary structure
SS confidence
Disorder																																																						?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	S	F	I	A	A	C	G	G	G	V	S	W	L	L	V	M	T	A	G	G	G	F	R	H	T	H	D	R	N	K	L	I	L	A	G	I	A	L	S	A	F	C	M	G	L	T	R	I	T	L	L	L	A	E	D	H	A	Y	G
Secondary structure
SS confidence
Disorder																						?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	F	Y	W	L	A	G	G	V	S	H	A	R	W	Q	D	V	W	Q	L	L	P	V	V	V	T	A	V	P	V	V	L	L	L	A	N	Q	L	N	L	L	N	L	S	D	S	T	A	H	T	L	G	V	N	L	T	R	L	R	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	I	N	M	L	V	L	L	L	V	G	A	C	V	S	V	A	G	P	V	A	F	I	G	L	L	V	P	H	L	A	R	F	W	A	G	F	D	Q	R	N	V	L	P	V	S	M	L	L	G	A	T	L	M	L	L	A	D	V	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.
Sequence		A	R	A	L	A	F	P	G	D	L	P	A	G	A	V	L	A	L	I	G	S	P	C	F	V	W	L	V	R	R	R	G
Secondary structure
SS confidence
Disorder																															?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1l7v chain A Region: 2 - 330 Aligned: 317 Modelled: 329 Confidence: 100.0% Identity: 30% Fold: ABC transporter involved in vitamin B12 uptake, BtuC Superfamily: ABC transporter involved in vitamin B12 uptake, BtuC Family: ABC transporter involved in vitamin B12 uptake, BtuC Phyre2 PDB 2nq2 chain A Region: 8 - 330 Aligned: 305 Modelled: 314 Confidence: 100.0% Identity: 30% PDB header:metal transport Chain: A: PDB Molecule:hypothetical abc transporter permease protein PDBTitle: an inward-facing conformation of a putative metal-chelate2 type abc transporter. Phyre2 PDB 1q1h chain A Region: 224 - 245 Aligned: 22 Modelled: 22 Confidence: 13.2% Identity: 23% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Transcription factor E/IIe-alpha, N-terminal domain Phyre2 1 d1l7va_ 2 c2nq2A_ 3 d1q1ha_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1l7va_ 100.0 30 Fold:ABC transporter involved in vitamin B12 uptake, BtuC Superfamily:ABC transporter involved in vitamin B12 uptake, BtuC Family:ABC transporter involved in vitamin B12 uptake, BtuC 2 c2nq2A_ 100.0 30 PDB header:metal transport Chain: A: PDB Molecule:hypothetical abc transporter permease protein PDBTitle: an inward-facing conformation of a putative metal-chelate2 type abc transporter. 3 d1q1ha_ 13.2 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Transcription factor E/IIe-alpha, N-terminal domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0