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Job DescriptionP27249
Confidence95.22%DateThu Jan 5 11:43:29 GMT 2012
Rank77Aligned Residues183
% Identity17%Templatec3g3nA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:high affinity camp-specific 3',5'-cyclic PDBTitle: pde7a catalytic domain in complex with 3-(2,6-2 difluorophenyl)-2-(methylthio)quinazolin-4(3h)-one
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   434.....440....... ..450 ....... ..460.........470.........480.........490.........500.....
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Query Sequence  GLLPMHRHSVLGAY. MPQ. . . . . . WSHIVGQ. MQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTE
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Template Sequence  TFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNA. . . VHAADVTQAMHCYLKE. . . . . . . . . PKLANSVTPWD
Template Known Secondary structure  TTTT

TS
TTSSSSS...TS.........TT

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   174.....180.........190.........200.........210.... .....220.........230 .........240.
 
   506...510.........520... ......530.........540.........550.........560
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Query Sequence  . . LIFIAALFHDIAKGRGGD. . . . . . . . . . . . . . . . . . . . . . . HSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMS
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Template Sequence  ILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLPLESRQQMETQIGALILAT
Template Known Secondary structure  TTTT

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   242.......250.........260.........270.........280.........290.........300.........310.........320.
 
   561........570.........580. ........590.........600.... .....610.........620.........
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Query Sequence  VTAQRRDIQDPEVIKQFAEEV. . . . . . . . . QTENRLRYLVCLTVADICATNET. . LWNSWKQSLLRELYFATEKQLRRGM
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Template Sequence  DISRQ. . . . . NEYLSLFRSHLDRGDLCLEDTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHL
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GGG.....T


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GGGS
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   322.... ...330.........340.........350.........360.........370.........380.........390......
 
   630...
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Query Sequence  QNTP
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Template Sequence  GVSP
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   397..400
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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