Job Description P27249 Confidence 80.33% Date Thu Jan 5 11:43:29 GMT 2012 Rank 121 Aligned Residues 185 % Identity 16% Template c3ecmA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:high affinity camp-specific and ibmx-insensitive PDBTitle: crystal structure of the unliganded pde8a catalytic domain Resolution 1.90 Å

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		434	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.									.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.
Predicted Secondary structure																								.	.	.	.	.	.	.	.
Query SS confidence																								.	.	.	.	.	.	.	.
Query Sequence		G	L	L	P	M	H	R	H	S	V	L	G	A	Y	M	P	Q	W	S	H	I	V	.	.	.	.	.	.	.	.	G	Q	M	Q	F	D	L	F	H	A	Y	T	V	D	E	H	T	I	R	V	M	L	K	L	E	S	F	A	S	E	E	T	R	Q	R	H	P	L	C	V	D	V	W	P	R	L	P	S	T	E
Query Conservation																								.	.	.	.	.	.	.	.
Alig confidence																								.	.	.	.	.	.	.	.												.	.	.																	.	.	.	.	.	.	.	.	.
Template Conservation																																											.	.	.																	.	.	.	.	.	.	.	.	.
Template Sequence		G	L	K	M	F	A	R	F	G	I	C	E	F	L	H	C	S	E	S	T	L	R	S	W	L	Q	I	I	E	A	N	Y	H	S	S	N	P	Y	H	N	S	.	.	.	T	H	S	A	D	V	L	H	A	T	A	Y	F	L	S	K	.	.	.	.	.	.	.	.	.	E	R	I	K	E	T	L	D	P	I	D
Template Known Secondary structure									T	T						T																T	S		T	T	S	S	S	S	S		.	.	.															T	S	.	.	.	.	.	.	.	.	.					T	T	S
Template Predicted Secondary structure																																											.	.	.																	.	.	.	.	.	.	.	.	.
Template SS confidence
		518	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.				.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.										.	.	.	.	.	580	.	.	.	.	.
				506	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.																	.	.	.	.	.	.				.	.	530	.	.	.	.	.	.	.	.	.	540								.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.
Predicted Secondary structure		.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							.	.	.														.	.	.	.	.	.	.
Query SS confidence		.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							.	.	.														.	.	.	.	.	.	.
Query Sequence		.	.	L	I	F	I	A	A	L	F	H	D	I	A	K	G	R	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	D	H	S	I	L	.	.	.	G	A	Q	D	V	V	H	F	A	E	L	H	G	.	.	.	.	.	.	.	L	N	S	R	E	T	Q	L	V	A	W	L	V	R	Q	H	L
Query Conservation		.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							.	.	.														.	.	.	.	.	.	.
Alig confidence		.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							.	.	.														.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	V	A	A	L	I	A	A	T	I	H	D	V	D	H	P	G	R	T	N	S	F	L	C	N	A	G	S	E	L	A	I	L	Y	N	D	T	A	V	L	E	S	H	H	A	A	L	A	F	Q	L	T	T	G	D	D	K	C	N	I	F	K	N	M	E	R	N	D	Y	R	T	L	R	Q	G	I	I	D	M	V
Template Known Secondary structure												T	T	T	T			S	S								T	T							T	T	T	S	S																T	S	T	T	T		T	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		586	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.
		558	.																				560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.			.	.	.	.	.	.	.	.	600	.	.	.	.			.	.	.	.	.	610	.	.	.	.
Predicted Secondary structure				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.														.	.
Query SS confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.														.	.
Query Sequence		L	M	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	V	T	A	Q	R	R	D	I	Q	D	P	E	V	I	K	Q	F	A	E	E	V	Q	T	E	N	R	L	R	Y	L	V	.	.	C	L	T	V	A	D	I	C	A	T	N	E	T	.	.	L	W	N	S	W	K	Q	S	L	L
Query Conservation				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.														.	.
Alig confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.														.	.
Template Conservation
Template Sequence		L	A	T	E	M	T	K	H	F	E	H	V	N	K	F	V	N	S	I	N	K	P	L	A	T	L	E	E	N	G	E	T	D	K	N	Q	E	V	I	N	T	M	L	R	T	P	E	N	R	T	L	I	K	R	M	L	I	K	C	A	D	V	S	N	P	C	R	P	L	Q	Y	C	I	E	W	A	A	R	I	S
Template Known Secondary structure			T	T		G	G	G												T								T	T	S		S													T	S																	T		G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		666	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.
		615	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Predicted Secondary structure
Query SS confidence
Query Sequence		R	E	L	Y	F	A	T	E	K	Q	L	R	R	G	M	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	E	Y	F	S	Q	T	D	E	E	K	Q	Q	G	L	P
Template Known Secondary structure															T
Template Predicted Secondary structure
Template SS confidence
		746	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions