Job Description P27249 Confidence 86.98% Date Thu Jan 5 11:43:29 GMT 2012 Rank 111 Aligned Residues 170 % Identity 15% Template c3bjcA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase; PDBTitle: crystal structure of the pde5a catalytic domain in complex2 with a novel inhibitor Resolution 2.00 Å

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		434	.	.	.	.	.	440	.	.	.	.	.	.	.				.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.				.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.
Predicted Secondary structure																.	.	.																			.	.	.																																									.	.
Query SS confidence																.	.	.																			.	.	.																																									.	.
Query Sequence		G	L	L	P	M	H	R	H	S	V	L	G	A	Y	.	.	.	M	P	Q	W	S	H	I	V	G	Q	M	Q	F	D	L	F	H	A	.	.	.	Y	T	V	D	E	H	T	I	R	V	M	L	K	L	E	S	F	A	S	E	E	T	R	Q	R	H	P	L	C	V	D	V	W	P	R	L	P	S	T	E	.	.
Query Conservation																.	.	.																			.	.	.																																									.	.
Alig confidence																.	.	.													.						.	.	.																					.	.	.	.	.	.	.	.	.												.	.
Template Conservation																															.																													.	.	.	.	.	.	.	.	.
Template Sequence		T	I	R	M	F	T	D	L	N	L	V	Q	N	F	Q	M	K	H	E	V	L	C	R	W	I	L	S	V	K	.	K	N	Y	R	K	N	V	A	Y	H	N	W	R	H	A	F	N	T	A	Q	C	M	F	A	A	L	K	A	.	.	.	.	.	.	.	.	.	G	K	I	Q	N	K	L	T	D	L	E	I	L
Template Known Secondary structure									T	T					T	T															.		T	S		T	T	S	S	S	S	S																	T	.	.	.	.	.	.	.	.	.	T			G	G	G	S
Template Predicted Secondary structure																															.																													.	.	.	.	.	.	.	.	.
Template SS confidence
		575	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.		.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.										.	.	.	.	.	.	.	.	640	.	.	.	.
		506	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.																			.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.							.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.
Predicted Secondary structure																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.
Query SS confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.
Query Sequence		L	I	F	I	A	A	L	F	H	D	I	A	K	G	R	G	G	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	H	S	I	L	G	A	Q	D	V	V	H	F	A	E	L	H	G	L	.	.	.	.	.	.	N	S	R	E	T	Q	L	V	A	W	L	V	R	Q	H	L	L	M	S	V
Query Conservation																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.
Alig confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.	.
Template Conservation
Template Sequence		A	L	L	I	A	A	L	S	H	D	L	D	H	R	G	V	N	N	S	Y	I	Q	R	S	E	H	P	L	A	Q	L	Y	C	H	S	I	M	E	H	H	H	F	D	Q	C	L	M	I	L	N	S	P	G	N	Q	I	L	S	G	L	S	I	E	E	Y	K	T	T	L	K	I	I	K	Q	A	I	L	A	T	D
Template Known Secondary structure										T	T	T	T				T	T			T	G	G	G	S	S		T	T						T	T															T	S	T	T			T	T	T	T	S																		T	T	S
Template Predicted Secondary structure
Template SS confidence
		645	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.
		562	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.										.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.			.	.	.	.	.	610	.	.	.	.	.	.	.	.
Predicted Secondary structure																								.	.	.	.	.	.	.	.	.																						.	.
Query SS confidence																								.	.	.	.	.	.	.	.	.																						.	.
Query Sequence		T	A	Q	R	R	D	I	Q	D	P	E	V	I	K	Q	F	A	E	E	V	Q	T	.	.	.	.	.	.	.	.	.	E	N	R	L	R	Y	L	V	C	L	T	V	A	D	I	C	A	T	N	E	T	.	.	L	W	N	S	W	K	Q	S	L	L	R	E	L	Y
Query Conservation																								.	.	.	.	.	.	.	.	.																						.	.
Alig confidence						.	.	.	.	.														.	.	.	.	.	.	.	.	.																						.	.
Template Conservation						.	.	.	.	.
Template Sequence		L	A	L	Y	.	.	.	.	.	I	K	R	R	G	E	F	F	E	L	I	R	K	N	Q	F	N	L	E	D	P	H	Q	K	E	L	F	L	A	M	L	M	T	A	C	D	L	S	A	I	T	K	P	W	P	I	Q	Q	R	I	A	E	L	V	A	T	E	F	F
Template Known Secondary structure						.	.	.	.	.													T	T				T	T	S																	T	G	G	G	G	S
Template Predicted Secondary structure						.	.	.	.	.
Template SS confidence
		725	.	.	.						.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions