Job Description P27249 Confidence 91.86% Date Thu Jan 5 11:43:29 GMT 2012 Rank 96 Aligned Residues 178 % Identity 16% Template c1xozA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase; PDBTitle: catalytic domain of human phosphodiesterase 5a in complex2 with tadalafil Resolution 1.37 Å

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		431	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.		.	.	450							.	.	.	.	.	.	.	.		.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.
Predicted Secondary structure																			.				.	.	.	.	.	.									.
Query SS confidence																			.				.	.	.	.	.	.									.
Query Sequence		V	R	R	G	L	L	P	M	H	R	H	S	V	L	G	A	Y	.	M	P	Q	.	.	.	.	.	.	W	S	H	I	V	G	Q	M	.	Q	F	D	L	F	H	A	Y	T	V	D	E	H	T	I	R	V	M	L	K	L	E	S	F	A	S	E	E	T	R	Q	R	H	P	L	C	V	D	V	W	P	R	L	P
Query Conservation																			.				.	.	.	.	.	.									.
Alig confidence																			.				.	.	.	.	.	.									.									.	.	.																														.	.	.	.
Template Conservation																																														.	.	.																														.	.	.	.
Template Sequence		A	L	C	T	I	R	M	F	T	D	L	N	L	V	Q	N	F	Q	M	K	H	E	V	L	C	R	W	I	L	S	V	K	K	N	Y	R	K	N	V	A	Y	H	N	W	.	.	.	R	H	A	F	N	T	A	Q	C	M	F	A	A	L	K	A	G	K	I	Q	N	K	L	T	D	L	E	I	L	.	.	.	.
Template Known Secondary structure												T	T					T	T																T	S		T	T	S	S	S	S	S		.	.	.																T	T			G	G	G	S							.	.	.	.
Template Predicted Secondary structure																																														.	.	.																														.	.	.	.
Template SS confidence
		572	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.				.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.
		503	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.																	.	.	.	.	.	.				.	.	530	.	.	.	.	.	.	.	.							.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.
Predicted Secondary structure																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							.	.	.												.	.	.	.	.	.
Query SS confidence																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							.	.	.												.	.	.	.	.	.
Query Sequence		S	T	E	L	I	F	I	A	A	L	F	H	D	I	A	K	G	R	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	D	H	S	I	L	.	.	.	G	A	Q	D	V	V	H	F	A	E	L	.	.	.	.	.	.	H	G	L	N	S	R	E	T	Q	L	V	A	W	L	V	R	Q	H	L
Query Conservation																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							.	.	.												.	.	.	.	.	.
Alig confidence		.	.	.																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							.	.	.												.	.	.	.	.	.
Template Conservation		.	.	.
Template Sequence		.	.	.	A	L	L	I	A	A	L	S	H	D	L	D	H	P	G	V	S	N	Q	F	L	I	N	T	N	S	E	L	A	L	M	Y	N	D	E	S	V	L	E	H	H	H	F	D	Q	C	L	M	I	L	N	S	P	G	N	Q	I	L	S	G	L	S	I	E	E	Y	K	T	T	L	K	I	I	K	Q	A	I
Template Known Secondary structure		.	.	.									T	T	T	T			S	S								T	T							T	T	T	S	S															T	S	T	T			T	T	T	T	S
Template Predicted Secondary structure		.	.	.
Template SS confidence
					645	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.
		558	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.										.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.			.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.
Predicted Secondary structure																												.	.	.	.	.	.	.	.	.																						.	.
Query SS confidence																												.	.	.	.	.	.	.	.	.																						.	.
Query Sequence		L	M	S	V	T	A	Q	R	R	D	I	Q	D	P	E	V	I	K	Q	F	A	E	E	V	Q	T	.	.	.	.	.	.	.	.	.	E	N	R	L	R	Y	L	V	C	L	T	V	A	D	I	C	A	T	N	E	T	.	.	L	W	N	S	W	K	Q	S	L	L	R	E	L	Y	F	A	T	E	K
Query Conservation																												.	.	.	.	.	.	.	.	.																						.	.
Alig confidence										.	.	.	.	.														.	.	.	.	.	.	.	.	.																						.	.
Template Conservation										.	.	.	.	.
Template Sequence		L	A	T	D	L	A	L	Y	.	.	.	.	.	I	K	R	R	G	E	F	F	E	L	I	R	K	N	Q	F	N	L	E	D	P	H	Q	K	E	L	F	L	A	M	L	M	T	A	C	D	L	S	A	I	T	K	P	W	P	I	Q	Q	R	I	A	E	L	V	A	T	E	F	F	D	Q	G	D	R
Template Known Secondary structure				T	S					.	.	.	.	.													T	T				T	T	S																	T	G	G	G	G	S
Template Predicted Secondary structure										.	.	.	.	.
Template SS confidence
		721	.	.	.	.	.	.	.						.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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