Return to main results Retrieve Phyre Job Id

Job DescriptionP27249
Confidence93.33%DateThu Jan 5 11:43:29 GMT 2012
Rank84Aligned Residues185
% Identity19%Templatec1xotB_
PDB info PDB header:hydrolaseChain: B: PDB Molecule:camp-specific 3',5'-cyclic phosphodiesterase 4b; PDBTitle: catalytic domain of human phosphodiesterase 4b in complex with2 vardenafil
Resolution2.34 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   434.....440....... ..450.........460..... ....470.........480.........490.........500.....
Predicted Secondary structure 


...












...













..
Query SS confidence 













. . .

















. . .







































. .
Query Sequence  GLLPMHRHSVLGAY. . . MPQWSHIVGQMQFDLFHA. . . YTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTE. .
Query Conservation   
  
   


   ...


   
    
 
 

 ...



 


  
  
            
             ..
Alig confidence 













...











.




...



















.........










..
Template Conservation     

    
     
    
  

  
 .  
   




  

 

 
    

  .........      
   
  
Template Sequence  MYAIFQERDLLKTFRISSDTFITYMMTLE. DHYHSDVAYHNSLHAADVAQSTHVLLST. . . . . . . . . PALDAVFTDLEIL
Template Known Secondary structure  TTTT

.TS
TTSSSSSTT
.........GGGTTTS
Template Predicted Secondary structure 






.








.........




Template SS confidence 















































































   196...200.........210.........220.... .....230.........240.........250.. .......260.....
 
   506...510.........520... ......530........ .540.........550.........560
Predicted Secondary structure 







.........................



Query SS confidence 

















. .














. . . . . . . . . . . . . . . . . . . . . . .





















Query Sequence  LIFIAALFHDIAKGRGGD. . HSILGAQDVVHFAEL. . . . . . . . . . . . . . . . . . . . . . . HGLNSRETQLVAWLVRQHLLMS
Query Conservation   
 

 







   
..

  

  
     
.......................
 
       
  

  

 

Alig confidence 

















..














.......................





















Template Conservation 






 


 


  
 


     

  
 
 



  
      

          
           

  



Template Sequence  AAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLAT
Template Known Secondary structure  TTTT

SS
TT
TTSSTTSSGGG
TTTTS
TT
Template Predicted Secondary structure 























Template SS confidence 















































































   266...270.........280.........290.........300.........310.........320.........330.........340.....
 
   561........570.........580... ......590.........600.... .....610.........620...
Predicted Secondary structure 








...............



..


Query SS confidence 






















. . . . . . . . . . . . . . .




















. .


















Query Sequence  VTAQRRDIQDPEVIKQFAEEVQT. . . . . . . . . . . . . . . ENRLRYLVCLTVADICATNET. . LWNSWKQSLLRELYFATEK
Query Conservation    
 



 

 

  

  
  ...............   
  
 


 

  



 .. 

 

  

  

  
  
Alig confidence 




.....












...............




















..


















Template Conservation 

  
.....   
                         
   
  

  



   

      
   
  

  


 
Template Sequence  DMSKH. . . . . MSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK
Template Known Secondary structure 
GGG.....T



TTS




ST
GGGS
Template Predicted Secondary structure  .....


















Template SS confidence 















































































   346...350 .........360.........370.........380.........390.........400.........410.........420
 
   624.....630...
Predicted Secondary structure 






Query SS confidence 









Query Sequence  QLRRGMQNTP
Query Conservation   
  
     
Alig confidence 









Template Conservation 
   

  
 
Template Sequence  ERERGMEISP
Template Known Secondary structure  T



T
Template Predicted Secondary structure 






Template SS confidence 









   421........430
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions