|   |
42 | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | |
. | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | C | L | I | I | H | D | N | N | K | L | G | D | L | I | V | L | S | S | I | Y | R | E | L | Y | S | K | G | V | K | I | T | L | L | T | N | R | K | G | G | E | F | L | S | N | . |
N | K | N | I | F | E | F | C | I | K | E | S | T | G | F | L | E | M | L | T | L | C | K | H | L | R | D | L | Q | F | D | I | V | L |
Query Conservation |   |
  |
|
|
|
|
|   |   |   |   |
|
|
|   |
|   |   |   |
|   |
|   |   |
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   | . |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |   |   |
| . | . |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
Template Sequence |   |
K | I | G | I | T | C | Y | P | G | . |
. |
G | S | G | V | V | G | T | E | L | G | K | Q | L | A | E | R | G | H | E | I | H | F | I | T | S | G | L | P | K | V | Y | P | N | I | Y | F | H | E | V | T | V | N | F | Q | Y | P | P | Y | D | L | A | L | A | S | K | M | A | E | V | A | Q | R | E | N | L | D | I | L | H |
Template Known Secondary structure |   |
 |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| S | S |
|
|
|
|
| T | T |  |  |  |  |
|
|
|
|
|
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | |
|
. | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
121 | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | P | F | E | T | M | P | S | F | K | H | S | L | I | L | S | S | L | K | D | S | Y | I | L | G | F | D | H | W | Y | K | R | Y | Y | S | F | Y | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | H | D | E | C | L | K | E | H | M | S | T | R | A | I | E | I | L | K | H | I | Y | G | E | G | K | F |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
V | H | Y | A | I | P | H | A | I | C | A | Y | L | A | K | Q | M | I | G | E | R | I | K | I | V | T | T | L | H | G | T | D | I | T | V | L | G | S | D | P | S | L | N | N | L | I | R | F | G | I | E | Q | S | D | V | V | T | A | V | S | H | S | L | I | N | E | T | H | E | L | V | K | P | N | K | D | I | Q | T | V |
Template Known Secondary structure |   |
 |
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S |  |  |  |  |  |
|
|  |  |  |  |  | T | T | T | T |
| T | T | T |  |  |  |  |  |  |  |  |  |  | S | S |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  | T |
|
| S | S |
|  |  |  |
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . |
  |
  |   |
186 | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | |
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
Query Sequence |   |
S | T | N | Y | D | L | H | L | P | V | D | V | E | D | K | I | K | E | F | I | G | D | T | R | I | V | I | I | N | P | L | G | A | K | K | I | C | R | L | T | F | E | Q | I | K | V | I | Y | Q | E | V | K | T | H | F | E | N | Y | R | I | I | F | T | G | L | P | Q | D | L | L | T | I | P | I | L | . |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | N | F | I | D | E | R | V | Y | F | K | R | D | M | T | Q | L | K | K | E | Y | G | I | S | K | I | L | I | H | I | S | N | F | R | K | V | K | R | . |
. |
V | Q | D | V | V | Q | A | F | A | K | I | V | T | E | V | D | A | K | L | L | L | V | G | D | G | P | E | F | C | T | I | L | Q | L | V | K | N | L | H | I |
Template Known Secondary structure |   |
|
|
|
|
| T | T | T |
|
|
|
|
|
|  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |
|
|
|
| G | G | G | T | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  | T | T | T |
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
172 | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | |
|
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
  |
  |   |
261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | I | E | T | L | P | F | D | E | F | I | Y | T | V | A | L | T | K | Y | S | D | F | V | I | S | V | D | T | . |
. |
. |
. |
. |
A | L | V | H | I | A | A | A | Y | H | K | P | T | L | A | F | Y | P | N | S | R | T | P | E | Y | P | S | H | L | I | W | S | P | N | H | H | K | S | I | Q | I | V | S | P | T | Y | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|   |   |
|   |
|   |
|
|   |
|
| . | . | . | . | . |
|   |   |
|
|
|
|
|
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . |   |
|   |   |   |   |   |
|   |
| . | . | . | . | . | . | . |
Template Sequence |   |
E | D | R | V | L | F | L | G | K | Q | D | N | V | A | E | L | L | A | M | S | D | L | M | L | L | L | S | E | K | E | S | F | G | L | V | L | L | E | A | M | A | C | G | V | P | C | I | G | T | R | V | G | G | I | P | E | . |
. |
. |
. |
. |
. |
. |
V | I | Q | H | G | D | T | G | Y | L | . |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
G | G | G | B |
|
|
| B | S |
| S |
| T |  |  |  |  |  | T |
| S |  |  |  |  |
|
| S |
|
| S |
|
|  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
|
| T | T | S | T | T | . | . | . | . | . | . | . | T |
|
| B | T | T | T |  |  |  | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 310 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
  |
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | K | D | I | D | T | E | T | L | T | N | S | V | K | R | L | S |
Query Conservation |   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|
|
Template Sequence |   |
C | E | V | G | D | T | T | G | V | A | D | Q | A | I | Q | L | L |
Template Known Secondary structure |   |
 |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
  |