Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	T	Q	I	K	V	R	G	Y	H	L	D	V	Y	Q	H	V	N	N	A	R	Y	L	E	F	L	E	E	A	R	W	D	G	L	E	N	S	D	S	F	Q	W	M	T	A	H	N	I	A	F	V	V	V	N	I	N	I	N	Y
Secondary structure
SS confidence
Disorder		?																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	R	P	A	V	L	S	D	L	L	T	I	T	S	Q	L	Q	Q	L	N	G	K	S	G	I	L	S	Q	V	I	T	L	E	P	E	G	Q	V	V	A	D	A	L	I	T	F	V	C	I	D	L	K	T	Q	K	A	L	A	L	E
Secondary structure
SS confidence
Disorder																																																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.
Sequence		G	E	L	R	E	K	L	E	Q	M	V	K
Secondary structure
SS confidence
Disorder											?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1njk chain A Region: 1 - 132 Aligned: 132 Modelled: 131 Confidence: 100.0% Identity: 98% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2o5u chain A domain 1 Region: 1 - 131 Aligned: 130 Modelled: 131 Confidence: 100.0% Identity: 21% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2nuj chain A domain 1 Region: 1 - 130 Aligned: 129 Modelled: 130 Confidence: 100.0% Identity: 15% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 3ck1 chain B Region: 1 - 132 Aligned: 131 Modelled: 132 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of a putative thioesterase (reut_a2179) from2 ralstonia eutropha jmp134 at 1.74 a resolution Phyre2 PDB 2oiw chain A domain 1 Region: 1 - 132 Aligned: 128 Modelled: 130 Confidence: 100.0% Identity: 18% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2oaf chain A domain 1 Region: 1 - 131 Aligned: 129 Modelled: 129 Confidence: 100.0% Identity: 15% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2gf6 chain A domain 1 Region: 1 - 128 Aligned: 126 Modelled: 128 Confidence: 100.0% Identity: 21% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 1s5u chain A Region: 1 - 127 Aligned: 126 Modelled: 127 Confidence: 100.0% Identity: 29% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2pzh chain C Region: 2 - 128 Aligned: 125 Modelled: 125 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: C: PDB Molecule:hypothetical protein hp_0496; PDBTitle: ybgc thioesterase (hp0496) from helicobacter pylori Phyre2 PDB 2w3x chain E Region: 1 - 132 Aligned: 132 Modelled: 132 Confidence: 100.0% Identity: 11% PDB header:hydrolase Chain: E: PDB Molecule:cale7; PDBTitle: crystal structure of a bifunctional hotdog fold2 thioesterase in enediyne biosynthesis, cale7 Phyre2 PDB 2xfl chain B Region: 1 - 130 Aligned: 130 Modelled: 130 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:dyne7; PDBTitle: induced-fit and allosteric effects upon polyene binding2 revealed by crystal structures of the dynemicin3 thioesterase Phyre2 PDB 2hx5 chain A domain 1 Region: 1 - 129 Aligned: 127 Modelled: 127 Confidence: 100.0% Identity: 21% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2ali chain A Region: 1 - 127 Aligned: 125 Modelled: 127 Confidence: 100.0% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein pa2801; PDBTitle: structure of protein of unknown function pa2801 from pseudomonas2 aeruginosa, putative thioesterase Phyre2 PDB 2ali chain A domain 1 Region: 1 - 127 Aligned: 125 Modelled: 127 Confidence: 100.0% Identity: 22% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2hlj chain A domain 1 Region: 1 - 132 Aligned: 129 Modelled: 131 Confidence: 100.0% Identity: 14% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2own chain A domain 1 Region: 1 - 128 Aligned: 127 Modelled: 128 Confidence: 100.0% Identity: 17% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: Acyl-ACP thioesterase-like Phyre2 PDB 2cye chain A domain 1 Region: 1 - 131 Aligned: 122 Modelled: 127 Confidence: 100.0% Identity: 27% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 1z54 chain A domain 1 Region: 3 - 131 Aligned: 125 Modelled: 127 Confidence: 100.0% Identity: 24% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 1lo7 chain A Region: 1 - 127 Aligned: 127 Modelled: 127 Confidence: 100.0% Identity: 17% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2egi chain E Region: 1 - 127 Aligned: 123 Modelled: 125 Confidence: 100.0% Identity: 23% PDB header:structural genomics, unknown function Chain: E: PDB Molecule:hypothetical protein aq_1494; PDBTitle: crystal structure of a hypothetical protein(aq1494) from aquifex2 aeolicus Phyre2 1 d1njka_ 2 d2o5ua1 3 d2nuja1 4 c3ck1B_ 5 d2oiwa1 6 d2oafa1 7 d2gf6a1 8 d1s5ua_ 9 c2pzhC_ 10 c2w3xE_ 11 c2xflB_ 12 d2hx5a1 13 c2aliA_ 14 d2alia1 15 d2hlja1 16 d2owna1 17 d2cyea1 18 d1z54a1 19 d1lo7a_ 20 c2egiE_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1njka_ 100.0 98 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 2 d2o5ua1 100.0 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 3 d2nuja1 100.0 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 4 c3ck1B_ 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of a putative thioesterase (reut_a2179) from2 ralstonia eutropha jmp134 at 1.74 a resolution 5 d2oiwa1 100.0 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 6 d2oafa1 100.0 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 7 d2gf6a1 100.0 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 8 d1s5ua_ 100.0 29 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 9 c2pzhC_ 100.0 24 PDB header:hydrolase Chain: C: PDB Molecule:hypothetical protein hp_0496; PDBTitle: ybgc thioesterase (hp0496) from helicobacter pylori 10 c2w3xE_ 100.0 11 PDB header:hydrolase Chain: E: PDB Molecule:cale7; PDBTitle: crystal structure of a bifunctional hotdog fold2 thioesterase in enediyne biosynthesis, cale7 11 c2xflB_ 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:dyne7; PDBTitle: induced-fit and allosteric effects upon polyene binding2 revealed by crystal structures of the dynemicin3 thioesterase 12 d2hx5a1 100.0 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 13 c2aliA_ 100.0 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein pa2801; PDBTitle: structure of protein of unknown function pa2801 from pseudomonas2 aeruginosa, putative thioesterase 14 d2alia1 100.0 22 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 15 d2hlja1 100.0 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 16 d2owna1 100.0 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 17 d2cyea1 100.0 27 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 18 d1z54a1 100.0 24 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 19 d1lo7a_ 100.0 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 20 c2egiE_ 100.0 23 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:hypothetical protein aq_1494; PDBTitle: crystal structure of a hypothetical protein(aq1494) from aquifex2 aeolicus 21 d2essa1 not modelled 100.0 11 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 22 c3hm0C_ not modelled 100.0 28 PDB header:hydrolase Chain: C: PDB Molecule:probable thioesterase; PDBTitle: crystal structure of probable thioesterase from bartonella2 henselae 23 c2ownA_ not modelled 99.9 17 PDB header:hydrolase Chain: A: PDB Molecule:putative oleoyl-[acyl-carrier protein] thioesterase; PDBTitle: crystal structure of oleoyl thioesterase (putative) (np_784467.1) from2 lactobacillus plantarum at 2.00 a resolution 24 c2essA_ not modelled 99.9 11 PDB header:hydrolase Chain: A: PDB Molecule:acyl-acp thioesterase; PDBTitle: crystal structure of an acyl-acp thioesterase (np_810988.1) from2 bacteroides thetaiotaomicron vpi-5482 at 1.90 a resolution 25 d2fuja1 not modelled 99.9 32 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 26 d2owna2 not modelled 99.8 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 27 d2essa2 not modelled 99.6 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 28 c3d6lA_ not modelled 99.3 15 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of cj0915, a hexameric hotdog fold2 thioesterase of campylobacter jejuni 29 c2eisA_ not modelled 99.3 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tthb207; PDBTitle: x-ray structure of acyl-coa hydrolase-like protein, tt1379, from2 thermus thermophilus hb8 30 d1ylia1 not modelled 99.2 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 31 d1vpma_ not modelled 99.2 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 32 c2qq2C_ not modelled 99.0 13 PDB header:hydrolase Chain: C: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase; PDBTitle: crystal structure of c-terminal domain of human acyl-coa thioesterase2 7 33 d1y7ua1 not modelled 99.0 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 34 c2v1oF_ not modelled 99.0 15 PDB header:hydrolase Chain: F: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase; PDBTitle: crystal structure of n-terminal domain of acyl-coa2 thioesterase 7 35 c3b7kA_ not modelled 98.9 12 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 12; PDBTitle: human acyl-coenzyme a thioesterase 12 36 d2gvha2 not modelled 98.8 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 37 d2gvha1 not modelled 98.8 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 38 d2f0xa1 not modelled 98.7 19 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 39 d2h4ua1 not modelled 98.7 19 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 40 c3lbeA_ not modelled 98.7 19 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein smu.793; PDBTitle: the crystal structure of smu.793 from streptococcus mutans ua159 bound2 to acetyl coa 41 c2gvhC_ not modelled 98.6 12 PDB header:hydrolase Chain: C: PDB Molecule:agr_l_2016p; PDBTitle: crystal structure of acyl-coa hydrolase (15159470) from agrobacterium2 tumefaciens at 2.65 a resolution 42 d2cy9a1 not modelled 98.5 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 43 c2qwzB_ not modelled 98.5 14 PDB header:hydrolase Chain: B: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase (tm1040_1390) from2 silicibacter sp. tm1040 at 2.15 a resolution 44 d1ixla_ not modelled 98.5 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 45 d1wlua1 not modelled 98.5 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 46 c3gekA_ not modelled 98.5 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative thioesterase yhda; PDBTitle: crystal structure of putative thioesterase yhda from lactococcus2 lactis. northeast structural genomics consortium target kr113 47 c2pimA_ not modelled 98.4 16 PDB header:hydrolase Chain: A: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase, phenylacetic acid2 degradation-related protein (reut_b4779) from ralstonia eutropha3 jmp134 at 2.20 a resolution 48 c3lwgB_ not modelled 98.4 10 PDB header:unknown function Chain: B: PDB Molecule:hp0420 homologue; PDBTitle: crystal structure of hp0420-homologue c46a from helicobacter2 felis 49 d2hboa1 not modelled 98.4 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 50 d1q4ua_ not modelled 98.4 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 51 c3nwzD_ not modelled 98.3 13 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:bh2602 protein; PDBTitle: crystal structure of bh2602 protein from bacillus halodurans with coa,2 northeast structural genomics consortium target bhr199 52 c2f3xA_ not modelled 98.3 6 PDB header:gene regulation Chain: A: PDB Molecule:transcription factor fapr; PDBTitle: crystal structure of fapr (in complex with effector)- a2 global regulator of fatty acid biosynthesis in b. subtilis 53 d1vh5a_ not modelled 98.3 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 54 c3s4kA_ not modelled 98.3 18 PDB header:hydrolase Chain: A: PDB Molecule:putative esterase rv1847/mt1895; PDBTitle: structure of a putative esterase rv1847/mt1895 from mycobacterium2 tuberculosis 55 c3e1eE_ not modelled 98.3 12 PDB header:hydrolase Chain: E: PDB Molecule:thioesterase family protein; PDBTitle: crystal structure of a thioesterase family protein from2 silicibacter pomeroyi. northeast structural genomics3 target sir180a 56 d1zkia1 not modelled 98.2 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 57 d2f41a1 not modelled 98.2 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 58 d1sc0a_ not modelled 98.2 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 59 d2fs2a1 not modelled 98.2 19 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 60 d2ov9a1 not modelled 98.2 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 61 c3f1tB_ not modelled 98.2 9 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein q9i3c8_pseae; PDBTitle: crystal structure of the q9i3c8_pseae protein from pseudomonas2 aeruginosa. northeast structural genomics consortium target par319a. 62 d1vh9a_ not modelled 98.1 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 63 c3hduB_ not modelled 98.0 8 PDB header:hydrolase Chain: B: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of a putative thioesterase (syn_01977) from2 syntrophus aciditrophicus sb at 2.50 a resolution 64 c3bnvD_ not modelled 98.0 14 PDB header:unknown function Chain: D: PDB Molecule:cj0977; PDBTitle: crystal structure of cj0977, a sigma28-regulated virulence protein2 from campylobacter jejuni. 65 c3e8pA_ not modelled 98.0 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the protein q8e9m7 from shewanella2 oneidensis related to thioesterase superfamily. northeast3 structural genomics consortium target sor246. 66 d2cwza1 not modelled 97.9 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:TTHA0967-like 67 c3dkzA_ not modelled 97.7 16 PDB header:hydrolase Chain: A: PDB Molecule:thioesterase superfamily protein; PDBTitle: crystal structure of the q7w9w5_borpa protein from2 bordetella parapertussis. northeast structural genomics3 consortium target bpr208c. 68 c3kuvB_ not modelled 97.6 11 PDB header:hydrolase Chain: B: PDB Molecule:fluoroacetyl coenzyme a thioesterase; PDBTitle: structural basis of the activity and substrate specificity of the2 fluoroacetyl-coa thioesterase flk - t42s mutant in complex with3 acetate. 69 c3e29C_ not modelled 97.5 13 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein q7we92_borbr; PDBTitle: x-ray structure of the protein q7we92_borbr from thioesterase2 superfamily. northeast structural genomics consortium target bor214a. 70 c3ir3B_ not modelled 97.5 10 PDB header:lyase Chain: B: PDB Molecule:3-hydroxyacyl-thioester dehydratase 2; PDBTitle: crystal structure of human 3-hydroxyacyl-thioester dehydratase 22 (htd2) 71 c3qooA_ not modelled 97.4 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of hot-dog-like taci_0573 protein from2 thermanaerovibrio acidaminovorans 72 d1yoca1 not modelled 97.4 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 73 c2prxB_ not modelled 97.3 12 PDB header:hydrolase Chain: B: PDB Molecule:thioesterase superfamily protein; PDBTitle: crystal structure of thioesterase superfamily protein (zp_00837258.1)2 from shewanella loihica pv-4 at 1.65 a resolution 74 d2q78a1 not modelled 97.1 8 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:TTHA0967-like 75 d1t82a_ not modelled 96.9 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 76 c2glvA_ not modelled 96.7 13 PDB header:lyase Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-acyl carrier protein PDBTitle: crystal structure of (3r)-hydroxyacyl-acyl carrier protein2 dehydratase(fabz) mutant(y100a) from helicobacter pylori 77 d2b3na1 not modelled 96.7 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 78 d1sh8a_ not modelled 96.7 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 79 d1iq6a_ not modelled 96.5 10 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 80 c3lmbA_ not modelled 96.5 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein olei01261 with unknown function2 from chlorobaculum tepidum tls 81 c3exzA_ not modelled 96.4 14 PDB header:lyase Chain: A: PDB Molecule:maoc-like dehydratase; PDBTitle: crystal structure of the maoc-like dehydratase from rhodospirillum2 rubrum. northeast structural genomics consortium target rrr103a. 82 d1q6wa_ not modelled 95.6 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 83 d2bi0a1 not modelled 95.2 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 84 d2c2ia1 not modelled 95.0 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 85 c2bi0A_ not modelled 94.7 17 PDB header:hypothetical protein Chain: A: PDB Molecule:hypothetical protein rv0216; PDBTitle: rv0216, a conserved hypothetical protein from mycobacterium2 tuberculosis that is essential for bacterial survival3 during infection, has a double hotdogfold 86 d1u1za_ not modelled 94.6 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:FabZ-like 87 c3khpB_ not modelled 94.5 19 PDB header:oxidoreductase Chain: B: PDB Molecule:maoc family protein; PDBTitle: crystal structure of a possible dehydrogenase from2 mycobacterium tuberculosis at 2.3a resolution 88 c3d6xA_ not modelled 94.1 16 PDB header:lyase Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; PDBTitle: crystal structure of campylobacter jejuni fabz 89 d1s9ca2 not modelled 93.5 6 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 90 d1pn2a1 not modelled 93.4 7 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 91 c3esiD_ not modelled 92.0 13 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from2 erwinia carotovora subsp. atroseptica. northeast3 structural genomics target ewr179 92 c3kh8B_ not modelled 91.3 12 PDB header:lyase Chain: B: PDB Molecule:maoc-like dehydratase; PDBTitle: crystal structure of maoc-like dehydratase from phytophthora capsici 93 d1z6ba1 not modelled 90.8 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:FabZ-like 94 d1s9ca1 not modelled 89.6 10 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 95 c1s9cK_ not modelled 87.6 12 PDB header:lyase Chain: K: PDB Molecule:peroxisomal multifunctional enzyme type 2; PDBTitle: crystal structure analysis of the 2-enoyl-coa hydratase 22 domain of human peroxisomal multifunctional enzyme type 2 96 d2bi0a2 not modelled 86.9 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 97 c1c8uA_ not modelled 86.0 6 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coa thioesterase ii; PDBTitle: crystal structure of the e.coli thioesterase ii, a2 homologue of the human nef-binding enzyme 98 c2cdhT_ not modelled 84.8 12 PDB header:transferase Chain: T: PDB Molecule:dehydratase; PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution. 99 d1tbua1 not modelled 81.9 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 100 c3rd7A_ not modelled 81.3 11 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coa thioesterase; PDBTitle: crystal structure of acyl-coa thioesterase from mycobacterium avium 101 c3bbjA_ not modelled 81.3 14 PDB header:hydrolase Chain: A: PDB Molecule:putative thioesterase ii; PDBTitle: crystal structure of a putative thioesterase ii (tfu_2367) from2 thermobifida fusca yx at 2.45 a resolution 102 d1pn2a2 not modelled 80.7 6 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 103 d1c8ua1 not modelled 80.0 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 104 c3rqbB_ not modelled 77.8 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of conserved protein of unknown function with hot2 dog fold from alicyclobacillus acidocaldarius 105 d1c8ua2 not modelled 77.1 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 106 c1pn2D_ not modelled 76.5 7 PDB header:lyase Chain: D: PDB Molecule:peroxisomal hydratase-dehydrogenase-epimerase; PDBTitle: crystal structure analysis of the selenomethionine labelled2 2-enoyl-coa hydratase 2 domain of candida tropicalis3 multifunctional enzyme type 2 107 c2uvaI_ not modelled 66.7 9 PDB header:transferase Chain: I: PDB Molecule:fatty acid synthase beta subunits; PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the beta subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400 108 c3cjyA_ not modelled 57.0 18 PDB header:hydrolase Chain: A: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of putative thioesterase (yp_496845.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.70 a resolution 109 c3omlA_ not modelled 45.8 8 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:peroxisomal multifunctional enzyme type 2, cg3415; PDBTitle: structure of full-length peroxisomal multifunctional enzyme type 22 from drosophila melanogaster 110 c2pfcA_ not modelled 37.2 9 PDB header:unknown function Chain: A: PDB Molecule:hypothetical protein rv0098/mt0107; PDBTitle: structure of mycobacterium tuberculosis rv0098 111 d1mkaa_ not modelled 34.3 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:beta-Hydroxydecanol thiol ester dehydrase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0