Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	T	V	P	G	L	C	W	L	C	R	M	P	L	A	L	G	H	W	G	I	C	S	V	C	S	R	A	T	R	T	D	K	T	L	C	P	Q	C	G	L	P	A	T	H	S	H	L	P	C	G	R	C	L	Q	K	P	P	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		W	Q	R	L	V	T	V	A	D	Y	A	P	P	L	S	P	L	I	H	Q	L	K	F	S	R	R	S	E	I	A	S	A	L	S	R	L	L	L	L	E	V	L	H	A	R	R	T	T	G	L	Q	L	P	D	R	I	V	S	V	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	W	Q	R	R	H	W	R	R	G	F	N	Q	S	D	L	L	C	Q	P	L	S	R	W	L	H	C	Q	W	D	S	E	A	V	T	R	T	R	A	T	A	T	Q	H	F	L	S	A	R	L	R	K	R	N	L	K	N	A	F	R
Secondary structure
SS confidence
Disorder																																									?	?	?	?	?	?	?	?								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.
Sequence		L	E	L	P	V	Q	G	R	H	M	V	I	V	D	D	V	V	T	T	G	S	T	V	A	E	I	A	Q	L	L	L	R	N	G	A	A	A	V	Q	V	W	C	L	C	R	T	L
Secondary structure
SS confidence
Disorder																																															?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1ecf chain A domain 1 Region: 83 - 222 Aligned: 122 Modelled: 140 Confidence: 99.8% Identity: 18% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1ecj chain B Region: 83 - 222 Aligned: 122 Modelled: 128 Confidence: 99.8% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer Phyre2 PDB 1gph chain 1 domain 1 Region: 83 - 222 Aligned: 117 Modelled: 128 Confidence: 99.7% Identity: 22% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1gph chain 1 Region: 83 - 222 Aligned: 117 Modelled: 128 Confidence: 99.7% Identity: 22% PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis Phyre2 PDB 1wd5 chain A Region: 82 - 223 Aligned: 122 Modelled: 142 Confidence: 99.6% Identity: 21% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1g2q chain A Region: 86 - 224 Aligned: 122 Modelled: 139 Confidence: 99.5% Identity: 21% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1zn7 chain A domain 1 Region: 85 - 224 Aligned: 122 Modelled: 140 Confidence: 99.5% Identity: 26% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1vch chain A domain 1 Region: 81 - 226 Aligned: 125 Modelled: 146 Confidence: 99.4% Identity: 19% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1a3c chain A Region: 94 - 224 Aligned: 114 Modelled: 121 Confidence: 99.4% Identity: 17% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 2dy0 chain A Region: 85 - 224 Aligned: 119 Modelled: 129 Confidence: 99.3% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli Phyre2 PDB 3kb8 chain A Region: 86 - 223 Aligned: 117 Modelled: 138 Confidence: 99.3% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 2.09 angstrom resolution structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames3 ancestor' in complex with gmp Phyre2 PDB 1w30 chain A Region: 91 - 223 Aligned: 114 Modelled: 133 Confidence: 99.3% Identity: 18% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1tc1 chain A Region: 87 - 225 Aligned: 115 Modelled: 124 Confidence: 99.3% Identity: 17% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1yfz chain A domain 1 Region: 86 - 224 Aligned: 118 Modelled: 139 Confidence: 99.3% Identity: 16% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1yfz chain A Region: 86 - 224 Aligned: 118 Modelled: 139 Confidence: 99.3% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis Phyre2 PDB 1j7j chain A Region: 86 - 225 Aligned: 112 Modelled: 125 Confidence: 99.3% Identity: 17% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1vdm chain A domain 1 Region: 82 - 225 Aligned: 117 Modelled: 144 Confidence: 99.3% Identity: 20% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1mzv chain A Region: 85 - 224 Aligned: 121 Modelled: 136 Confidence: 99.3% Identity: 22% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1o57 chain A domain 2 Region: 85 - 223 Aligned: 118 Modelled: 128 Confidence: 99.2% Identity: 16% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1g9s chain A Region: 87 - 225 Aligned: 108 Modelled: 125 Confidence: 99.2% Identity: 18% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 2kre chain A Region: 7 - 82 Aligned: 57 Modelled: 57 Confidence: 85.5% Identity: 12% PDB header:protein binding Chain: A: PDB Molecule:ubiquitin conjugation factor e4 b; PDBTitle: solution structure of e4b/ufd2a u-box domain Phyre2 PDB 2ko5 chain A Region: 5 - 47 Aligned: 43 Modelled: 43 Confidence: 83.3% Identity: 21% PDB header:transcription Chain: A: PDB Molecule:ring finger protein z; PDBTitle: nmr solution structure of lfv-z Phyre2 1 d1ecfa1 2 c1ecjB_ 3 d1gph11 4 c1gph1_ 5 d1wd5a_ 6 d1g2qa_ 7 d1zn7a1 8 d1vcha1 9 d1a3ca_ 10 c2dy0A_ 11 c3kb8A_ 12 d1w30a_ 13 d1tc1a_ 14 d1yfza1 15 c1yfzA_ 16 d1j7ja_ 17 d1vdma1 18 d1mzva_ 19 d1o57a2 20 d1g9sa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 c2kreA_ 71 72 c2ko5A_ 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1ecfa1 99.8 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 2 c1ecjB_ 99.8 18 PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer 3 d1gph11 99.7 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 4 c1gph1_ 99.7 22 PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis 5 d1wd5a_ 99.6 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 6 d1g2qa_ 99.5 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 7 d1zn7a1 99.5 26 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 8 d1vcha1 99.4 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 9 d1a3ca_ 99.4 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 10 c2dy0A_ 99.3 18 PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli 11 c3kb8A_ 99.3 17 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 2.09 angstrom resolution structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames3 ancestor' in complex with gmp 12 d1w30a_ 99.3 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 13 d1tc1a_ 99.3 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 14 d1yfza1 99.3 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 15 c1yfzA_ 99.3 16 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis 16 d1j7ja_ 99.3 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 17 d1vdma1 99.3 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 18 d1mzva_ 99.3 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 19 d1o57a2 99.2 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 20 d1g9sa_ 99.2 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 21 d2igba1 not modelled 99.2 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 22 c2wnsB_ not modelled 99.2 20 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp) 23 d1p17b_ not modelled 99.2 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 24 d1ufra_ not modelled 99.2 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 25 d1hgxa_ not modelled 99.2 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 26 c1o57A_ not modelled 99.2 16 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 27 d1y0ba1 not modelled 99.2 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 28 c3o7mD_ not modelled 99.2 13 PDB header:transferase Chain: D: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 1.98 angstrom resolution crystal structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-2) from bacillus anthracis str. 'ames3 ancestor' 29 d1pzma_ not modelled 99.1 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 30 c3dezA_ not modelled 99.1 17 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 streptococcus mutans 31 c1pzmB_ not modelled 99.1 19 PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hgprt-ase from leishmania tarentolae in complex2 with gmp 32 d2aeea1 not modelled 99.1 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 33 c2ywtA_ not modelled 99.1 23 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hypoxanthine-guanine2 phosphoribosyltransferase with gmp from thermus3 thermophilus hb8 34 d1l1qa_ not modelled 99.1 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 35 c3mjdA_ not modelled 99.1 15 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.9 angstrom crystal structure of orotate2 phosphoribosyltransferase (pyre) francisella tularensis. 36 d1z7ga1 not modelled 99.1 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 37 c2p1zA_ not modelled 99.0 22 PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase; PDBTitle: crystal structure of phosphoribosyltransferase from corynebacterium2 diphtheriae 38 d1lh0a_ not modelled 99.0 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 39 c3efhB_ not modelled 99.0 24 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1 40 c2yzkC_ not modelled 99.0 24 PDB header:transferase Chain: C: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 aeropyrum pernix 41 d1cjba_ not modelled 98.9 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 42 c2c4kD_ not modelled 98.9 21 PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39) 43 d1qb7a_ not modelled 98.9 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 44 d1dkua2 not modelled 98.9 24 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 45 c3lpnB_ not modelled 98.9 26 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of the phosphoribosylpyrophosphate (prpp) synthetase2 from thermoplasma volcanium in complex with an atp analog (ampcpp). 46 c3m3hA_ not modelled 98.9 12 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.75 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase from bacillus anthracis str. 'ames3 ancestor' 47 d1u9ya2 not modelled 98.9 33 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 48 c3n2lA_ not modelled 98.9 15 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 2.1 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase (pyre) from vibrio cholerae o1 biovar eltor3 str. n16961 49 c2przB_ not modelled 98.8 15 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase 1; PDBTitle: s. cerevisiae orotate phosphoribosyltransferase complexed2 with omp 50 c2jkzB_ not modelled 98.8 18 PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: saccharomyces cerevisiae hypoxanthine-guanine2 phosphoribosyltransferase in complex with gmp (guanosine 5'3 -monophosphate) (orthorhombic crystal form) 51 c1dkrB_ not modelled 98.8 21 PDB header:transferase Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase; PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation. 52 d2c4ka2 not modelled 98.8 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 53 d1fsga_ not modelled 98.8 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 54 c3qw4B_ not modelled 98.7 26 PDB header:transferase, lyase Chain: B: PDB Molecule:ump synthase; PDBTitle: structure of leishmania donovani ump synthase 55 c3dahB_ not modelled 98.7 25 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: 2.3 a crystal structure of ribose-phosphate pyrophosphokinase from2 burkholderia pseudomallei 56 c1u9yD_ not modelled 98.6 29 PDB header:transferase Chain: D: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of phosphoribosyl diphosphate synthase2 from methanocaldococcus jannaschii 57 c2jbhA_ not modelled 98.4 28 PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase domain-containing protein 1; PDBTitle: human phosphoribosyl transferase domain containing 1 58 d1nula_ not modelled 98.4 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 59 c2ehjA_ not modelled 98.1 30 PDB header:transferase Chain: A: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of uracil phosphoribosyl transferase 60 d1i5ea_ not modelled 98.1 30 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 61 c2e55D_ not modelled 98.0 20 PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of aq2163 protein from aquifex aeolicus 62 d1dqna_ not modelled 97.9 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 63 d1o5oa_ not modelled 97.9 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 64 d1xtta1 not modelled 97.8 12 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 65 c3dmpD_ not modelled 97.4 22 PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: 2.6 a crystal structure of uracil phosphoribosyltransferase2 from burkholderia pseudomallei 66 d1v9sa1 not modelled 97.4 23 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 67 d1bd3a_ not modelled 97.2 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 68 d1u9ya1 not modelled 92.7 14 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 69 d2c4ka1 not modelled 90.3 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 70 c2kreA_ 85.5 12 PDB header:protein binding Chain: A: PDB Molecule:ubiquitin conjugation factor e4 b; PDBTitle: solution structure of e4b/ufd2a u-box domain 71 d1dkua1 not modelled 83.4 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 72 c2ko5A_ 83.3 21 PDB header:transcription Chain: A: PDB Molecule:ring finger protein z; PDBTitle: nmr solution structure of lfv-z 73 c1z6uA_ not modelled 75.9 16 PDB header:ligase Chain: A: PDB Molecule:np95-like ring finger protein isoform b; PDBTitle: np95-like ring finger protein isoform b [homo sapiens] 74 c2csyA_ not modelled 72.2 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:zinc finger protein 183-like 1; PDBTitle: solution structure of the ring domain of the zinc finger2 protein 183-like 1 75 c2k0aA_ not modelled 70.8 22 PDB header:metal binding protein Chain: A: PDB Molecule:pre-mrna-splicing factor rds3; PDBTitle: 1h, 15n and 13c chemical shift assignments for rds3 protein 76 d1wgma_ not modelled 69.4 11 Fold:RING/U-box Superfamily:RING/U-box Family:U-box 77 c2ecyA_ not modelled 68.1 19 PDB header:apoptosis Chain: A: PDB Molecule:tnf receptor-associated factor 3; PDBTitle: solution structure of the zinc finger, c3hc4 type (ring2 finger)" domain of tnf receptor-associated factor 3 78 d2gmga1 not modelled 66.1 24 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:PF0610-like 79 c3fl2A_ not modelled 65.9 21 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase uhrf1; PDBTitle: crystal structure of the ring domain of the e3 ubiquitin-2 protein ligase uhrf1 80 c2f42A_ not modelled 64.8 12 PDB header:chaperone Chain: A: PDB Molecule:stip1 homology and u-box containing protein 1; PDBTitle: dimerization and u-box domains of zebrafish c-terminal of hsp702 interacting protein 81 d1wfga_ not modelled 64.6 15 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 82 c3eggC_ not modelled 64.1 21 PDB header:hydrolase Chain: C: PDB Molecule:spinophilin; PDBTitle: crystal structure of a complex between protein phosphatase 1 alpha2 (pp1) and the pp1 binding and pdz domains of spinophilin 83 c2komA_ not modelled 63.5 20 PDB header:signaling protein Chain: A: PDB Molecule:partitioning defective 3 homolog; PDBTitle: solution structure of humar par-3b pdz2 (residues 451-549) 84 d1wifa_ not modelled 62.1 23 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 85 d1t1ha_ not modelled 61.9 16 Fold:RING/U-box Superfamily:RING/U-box Family:U-box 86 c2d8tA_ not modelled 61.4 15 PDB header:metal binding protein Chain: A: PDB Molecule:ring finger protein 146; PDBTitle: solution structure of the ring domain of the human ring2 finger protein 146 87 d1jm7a_ not modelled 61.2 21 Fold:RING/U-box Superfamily:RING/U-box Family:RING finger domain, C3HC4 88 c2djbA_ not modelled 61.0 20 PDB header:gene regulation Chain: A: PDB Molecule:polycomb group ring finger protein 6; PDBTitle: solution structure of the ring domain of the human polycomb2 group ring finger protein 6 89 d1ur6b_ not modelled 60.5 43 Fold:RING/U-box Superfamily:RING/U-box Family:RING finger domain, C3HC4 90 c3mmnA_ not modelled 60.0 17 PDB header:transferase Chain: A: PDB Molecule:histidine kinase homolog; PDBTitle: crystal structure of the receiver domain of the histidine kinase cki12 from arabidopsis thaliana complexed with mg2+ 91 d2fiya1 not modelled 59.5 31 Fold:FdhE-like Superfamily:FdhE-like Family:FdhE-like 92 d1miob_ not modelled 59.1 14 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 93 c2eciA_ not modelled 58.8 23 PDB header:metal binding protein Chain: A: PDB Molecule:tnf receptor-associated factor 6; PDBTitle: solution structure of the ring domain of the human tnf2 receptor-associated factor 6 protein 94 d1dgsa1 not modelled 58.5 33 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:NAD+-dependent DNA ligase, domain 3 95 d2baya1 not modelled 57.8 10 Fold:RING/U-box Superfamily:RING/U-box Family:U-box 96 d2cssa1 not modelled 56.6 15 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 97 c2y43B_ not modelled 56.3 30 PDB header:ligase Chain: B: PDB Molecule:e3 ubiquitin-protein ligase rad18; PDBTitle: rad18 ubiquitin ligase ring domain structure 98 c2ecmA_ not modelled 56.0 20 PDB header:metal binding protein Chain: A: PDB Molecule:ring finger and chy zinc finger domain- PDBTitle: solution structure of the ring domain of the ring finger2 and chy zinc finger domain-containing protein 1 from mus3 musculus 99 c3bvoA_ not modelled 55.9 27 PDB header:chaperone Chain: A: PDB Molecule:co-chaperone protein hscb, mitochondrial precursor; PDBTitle: crystal structure of human co-chaperone protein hscb 100 d1e4ua_ not modelled 55.4 40 Fold:RING/U-box Superfamily:RING/U-box Family:RING finger domain, C3HC4 101 c2cklA_ not modelled 54.7 19 PDB header:transcription Chain: A: PDB Molecule:polycomb group ring finger protein 4; PDBTitle: ring1b-bmi1 e3 catalytic domain structure 102 d1iyma_ not modelled 54.3 27 Fold:RING/U-box Superfamily:RING/U-box Family:RING finger domain, C3HC4 103 c1nsfA_ not modelled 54.1 16 PDB header:protein transport Chain: A: PDB Molecule:n-ethylmaleimide sensitive factor; PDBTitle: d2 hexamerization domain of n-ethylmaleimide sensitive factor (nsf) 104 c2i04B_ not modelled 53.7 28 PDB header:peptide binding protein Chain: B: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: x-ray crystal structure of magi-1 pdz1 bound to the c-2 terminal peptide of hpv18 e6 105 c2jrpA_ not modelled 53.6 28 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative cytoplasmic protein; PDBTitle: solution nmr structure of yfgj from salmonella typhimurium2 modeled with two zn+2 bound, northeast structural genomics3 consortium target str86 106 c1u37A_ not modelled 53.4 8 PDB header:protein transport Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding, PDBTitle: auto-inhibition mechanism of x11s/mints family scaffold2 proteins revealed by the closed conformation of the tandem3 pdz domains 107 c1u38A_ not modelled 53.4 8 PDB header:protein transport Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding, PDBTitle: auto-inhibition mechanism of x11s/mints family scaffold2 proteins revealed by the closed conformation of the tandem3 pdz domains 108 c2opgB_ not modelled 52.9 21 PDB header:structural protein Chain: B: PDB Molecule:multiple pdz domain protein; PDBTitle: the crystal structure of the 10th pdz domain of mpdz 109 d1weoa_ not modelled 52.3 31 Fold:RING/U-box Superfamily:RING/U-box Family:RING finger domain, C3HC4 110 d1vaea_ not modelled 51.9 26 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 111 d2c2vv1 not modelled 51.6 9 Fold:RING/U-box Superfamily:RING/U-box Family:U-box 112 d1ueqa_ not modelled 49.6 25 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 113 d1rmda2 not modelled 49.3 26 Fold:RING/U-box Superfamily:RING/U-box Family:RING finger domain, C3HC4 114 c3tsuA_ not modelled 49.3 22 PDB header:transferase Chain: A: PDB Molecule:transcriptional regulatory protein; PDBTitle: crystal structure of e. coli hypf with amp-pnp and carbamoyl phosphate 115 d1v6ba_ not modelled 49.3 22 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 116 c2hcuA_ not modelled 48.5 16 PDB header:lyase Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit; PDBTitle: crystal structure of smu.1381 (or leud) from streptococcus2 mutans 117 d1t2ma1 not modelled 48.4 21 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 118 c2owoA_ not modelled 48.3 16 PDB header:ligase/dna Chain: A: PDB Molecule:dna ligase; PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate 119 c3grfA_ not modelled 48.3 9 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia 120 c2vsvB_ not modelled 47.1 21 PDB header:protein-binding Chain: B: PDB Molecule:rhophilin-2; PDBTitle: crystal structure of the pdz domain of human rhophilin-2

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0