|   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
|
. | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | |
|
|
. | . | . | . | 120 | . | . | . | . | . | . | . | |
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|  |  |  |
|
|
|
|
|  | . |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | A | L | A | E | S | V | K | N | I | F | G | Y | Q | . |
. |
Y | T | I | P | T | H | Q | G | R | G | A | E | Q | I | Y | I | P | V | L | I | K | . |
. |
. |
K | R | E | Q | E | K | G | L | D | R | S | K | . |
M | V | A | F | S | N | Y | F | F | D | T | T | Q | G | H | S | Q | I | N | G | C | T | V | R | N | V | Y |
Query Conservation |   |
  |   |
|
|
|   |   |
|   |
|   |
|   |
| . | . |   |   |
|   |   |   |
|
|
|   |
|   |   |
|
|   |   |   |   |   |   | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
Template Sequence |   |
E | K | A | V | A | L | L | G | S | L | L | N | N | K | D | A | Y | G | H | I | V | S | G | G | T | E | A | N | L | X | A | L | R | C | I | K | N | I | W | R | E | K | R | R | K | G | L | S | K | N | E | H | P | K | I | I | V | P | I | T | A | H | F | S | F | E | K | G | R | E | X | X | D | L | E | Y | I | Y | A | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
| T | T |
|  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| S | S |
|  |  |  |  |  | T | T |
|
| T |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 |
  |
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | K | E | A | F | D | T | G | V | R | Y | D | F | K | G | N | F | D | L | E | G | L | E | R | G | I | E | E | V | G | P | N | N | V | P | Y | I | V | A | T | I | T | S | N | S | A | G | G | Q | P | V | S | L | A | N | L | K | A | M | Y | S | I | A | K | K | Y | D | I | P | V | V | M | D | S | A | R | F | A | E | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |
Template Sequence |   |
I | K | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | Y | T | I | D | E | K | F | V | K | D | A | V | E | D | . |
. |
. |
Y | D | V | D | G | I | I | G | I | A | G | T | T | E | L | G | . |
. |
. |
. |
T | I | D | N | I | E | E | L | S | K | I | A | K | E | N | N | I | Y | I | H | V | D | A | A | F | G | G | L | V |
Template Known Secondary structure |   |
B |
| T | . | . | . | . | . | . | . | . | . | . | T | S | S | B |
|  |  |  |  |  |  |  |  |  |  | . | . | . | S |
|
|
|  |  |  |  |  | B | S |
| T | T | T |
| . | . | . | . |
| B |
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
| T | T | G | G | G | T |
Template Predicted Secondary structure |   |
 |
|
| . | . | . | . | . | . | . | . | . | . |
|
|  |  |
|  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
151 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | |
|
|
. | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
|
. | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . |
  |
  |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | |
. | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  | . |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Y | F | I | K | Q | R | E | A | E | Y | K | D | W | T | I | E | Q | I | T | R | E | T | Y | K | Y | A | D | M | L | A | M | S | A | K | K | D | A | M | V | P | M | G | . |
G | L | L | C | M | K | D | D | S | F | F | D | V | Y | T | E | C | R | T | L | C | V | V | Q | E | G | F | P | T | Y | G | G | L | E | G | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |
|   |
|   |
| . |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | P | F | L | D | D | K | Y | K | K | K | G | V | N | Y | K | F | D | F | S | L | G | V | . |
. |
. |
. |
D | S | I | T | I | D | P | H | K | X | G | H | C | P | I | P | S | G | G | I | L | F | K | D | I | G | Y | K | R | Y | L | D | V | D | A | P | Y | L | T | E | T | R | Q | A | T | I | L | G | T | R | V | G | F |
Template Known Secondary structure |   |
G | G | G |
|
| G | G | G |
|
| T | T |
|
|
|
|
| S | G | G | G | T |
| . | . | . | . | S |  |  |  |
|
| T | T | T | T | T |
|
|
| S | S |
|  |  |  |  |  | S | S | G | G | G | G | G | G | T |
|  |  |
| T | T | S | S | S | S |  |  |
| S | S |
| S | S |
|
| S |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
214 | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | |
|
|
|
. | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
  |
  |   |
314 | . | . | . | . | . | 320 | . | . | . | . | . | . | . | |
|
|
. | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | |
. | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | M | E | R | L | A | V | G | L | Y | D | G | M | N | . |
. |
. |
L | D | W | L | A | Y | R | I | A | Q | V | Q | Y | L | V | D | G | L | E | E | I | G | V | . |
V | C | Q | Q | A | G | G | H | A | A | F | V | D | A | G | K | L | L | P | H | I | P | A | D | Q | F | P | A | Q | A | L | A | C | E | L | Y | K | V | A |
Query Conservation |   |
  |   |   |
|   |
|   |
|
|   |   |   |   |   | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   | . |   |
|   |   |   |
|
|
|   |
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
G | G | A | C | T | Y | A | V | L | R | Y | L | G | R | E | G | Q | R | K | I | V | N | E | C | X | E | N | T | L | Y | L | Y | K | K | L | K | E | N | N | F | K | P | V | I | E | P | I | L | N | I | V | A | I | E | D | E | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| B | S | S |
|
| S | S | S |  |  |  |  |  |
| T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | I | R | A | V | E | I | G | S | F | L | L | G | R | D | P | K | T | G | K | Q | L | P | C | P | A | E | L | L | R | L | T | I | P | R | A | T | Y | T | Q | T | H | M | D | F | I | I | E | A | F | K | H | V | K |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |
|
|   |   |
|   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   | . | . |   |   |
|
|
|   | . |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |
|   |   |
|
|
Template Sequence |   |
. |
. |
. |
Y | K | E | V | C | K | K | L | R | D | R | G | I | Y | V | S | V | C | N | C | V | . |
. |
K | A | L | R | I | V | . |
V | X | P | H | I | K | R | E | H | I | D | N | F | I | E | I | L | N | S | I | K |
Template Known Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
|  |  |
| S | S | S | . | . | S |  |  |  |  |  | . |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
| . | . |
|  |  |  |  |  | . |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
347 | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | |
|
. | . | 370 | . | . | . | |
. | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . |
  |