|   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
|
|
. | . | . | . | . | 100 | |
. | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | Y | A | L | A | E | S | V | K | N | I | F | G | Y | Q | . |
. |
. |
Y | T | I | P | T | H | . |
Q | G | R | G | A | E | Q | I | Y | I | P | V | L | I | K | K | R | E | Q | E | K | G | L | D | R | S | K | M | V | A | F | S | N | Y | F | F | D | T | T | Q | G | H | S | Q | I | N | G | C | T | V | R | N | V | Y | I |
Query Conservation |   |
  |   |   |
|
|
|   |   |
|   |
|   |
|   |
| . | . | . |   |   |
|   |   |   | . |
|
|
|   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |
|
|   |
|   |
|   |   |   |   |   |   |
|
|
|   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . |   |
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
I | N | N | T | E | N | L | V | R | E | L | L | A | V | P | D | N | Y | K | V | I | F | L | Q | G | G | G | C | G | Q | F | S | A | V | P | L | N | L | I | G | L | K | . |
. |
. |
. |
. |
. |
A | G | R | C | A | D | Y | V | V | T | G | A | W | S | A | K | A | A | E | E | A | K | K | F | G | T | I | N | I | V | H | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | S | . | . | . | . | . | . | T | T |
|  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  | T | T | T | S |  |  |  |  |
| S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
53 | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . |
  |
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | E | A | F | D | T | G | V | R | Y | D | F | K | G | N | F | D | L | E | G | L | E | R | G | I | E | E | V | G | P | N | N | V | P | Y | I | V | A | T | I | T | S | N | S | A | G | G | Q | P | V | S | L | A | N | L | K | A | M | Y | S | I | A | K | K | Y | D | I | P | V | V | M | D | S | A | R | F | A | E | N | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |
|
|   |   |   |   |   |   |
|   |
| . |
|   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |
Template Sequence |   |
K | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | S | Y | T | K | I | P | D | P | S | T | W | N | L | N | . |
. |
. |
P | D | A | S | Y | V | Y | Y | C | A | N | E | T | V | H | . |
G | V | E | F | D | . |
. |
. |
. |
. |
. |
. |
. |
F | I | P | D | V | K | G | A | V | L | V | C | D | M | S | S | N | F | L | S | K |
Template Known Secondary structure |   |
|
| . | . | . | . | . | . | . | . | . | . | S | S | S |
| S |
|
|
| G | G | G |
|
|
|
| . | . | . | T | T |
| S |
|  |  |  |  | S |  |  | T | T | T | . | T |  |  |
| S | . | . | . | . | . | . | . | . | S |
|
|
|
| T | T |
|
|  |  |  |  |
| T | T | T | T | T | S | S |
Template Predicted Secondary structure |   |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . |
|
|  |  |
| . | . | . | . | . | . | . | . |
|
|  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
127 | . | |
|
|
|
|
|
|
|
|
|
. | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | |
|
|
. | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | |
. | 160 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
  |
  |   |
236 | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
|
|
. | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | F | I | K | Q | R | E | A | E | Y | K | D | W | T | I | E | Q | I | T | R | E | T | Y | K | Y | A | D | M | L | A | M | S | A | K | K | D | A | M | V | P | M | G | G | L | L | C | M | K | D | D | S | F | F | D | V | Y | T | E | C | R | T | L | . |
. |
. |
C | V | V | Q | E | G | F | P | T | Y | G | G | L | E | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |
|   |
|   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
P | V | D | V | S | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | G | V | I | F | A | G | A | Q | K | N | V | G | S | A | G | V | T | V | V | I | V | R | D | D | L | L | G | F | A | L | R | E | C | P | S | V | L | E | Y | K | V | Q | A | G | N | S | S | L | Y | N | T | P | P | C |
Template Known Secondary structure |   |
|
|
| G | G | G | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S |  |  |  |  |  | G | G | G | T | T | S |
| T | T |
|  |  |  |  |  |  | T | T | S |
| S |
|
|
| T | T | S |
| G | G | G |
|  |  |  |  |  | T | T | T | T |
| S | S |
|
|
|  |
Template Predicted Secondary structure |   |
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
185 | . | . | . | . | 190 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . |
  |
  |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | |
. | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | A | M | E | R | L | A | V | G | L | Y | D | G | M | N | L | D | W | L | A | Y | R | I | A | Q | V | Q | Y | L | V | D | G | L | E | E | I | G | V | V | C | Q | Q | A | G | G | H | A | A | F | V | . |
D | A | G | K | L | L | P | H | I | P | A | D | Q | F | P | A | Q | A | L | A | C | E | L | Y | K | V | A | G | I |
Query Conservation |   |
  |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|   |
| . |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
Template Sequence |   |
F | S | I | Y | V | M | G | L | V | L | E | W | I | K | N | N | G | G | A | A | A | M | E | K | L | S | S | I | K | S | Q | T | I | Y | E | I | . |
. |
. |
I | D | N | S | Q | G | F | Y | V | C | P | V | E | P | Q | N | R | S | K | M | N | I | P | F | R | I | G | N | A | K | G | D | D | A | L | E | K | R | F | L | D |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  | T | S | T | T | S |  |  |
|
| S |
| G | G | G | B |
| S | S |  |  |  |  |  |  | S | S | T | T |
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | |
|
|
. | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
  |
  |   |
392 | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | V | E | I | G | S | F | L | L | G | R | D | P | K | T | G | K | Q | L | P | C | P | A | E | L | L | R | L | T | I | P | R | A | T | Y | T | Q | T | H | M | D | F | I | I | E | A | F | K | H | V | K | E | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |
|
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   | . |
|   |
|
|
|   |   |
|
|   |   |
|   |
|   |   |   |   |
Template Sequence |   |
K | A | L | E | L | N | M | L | . |
. |
. |
. |
. |
. |
. |
. |
S | L | K | G | H | R | S | V | G | G | I | R | A | S | L | Y | N | A | V | . |
T | I | E | D | V | Q | K | L | A | A | F | M | K | K | F | L | E | M |
Template Known Secondary structure |   |
 |  |  |  | T | T |  |  | . | . | . | . | . | . | . | . | S |
| B |
|
| T | T | T |
| S |  |  |  |  |
|
| T | T | S | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
323 | . | . | . | . | . | . | 330 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | |
350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . |
  |