|   |
44 | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | T | D | F | K | V | N | A | A | K | A | L | S | P | Y | A | S | A | I | L | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | Q | Q | F | C | Y | R | Q | V | V | E | Q | N | A | I | A | K | S | C | A | M | I | V | A | A | D | E | F | I | P | G | N | G | I | P | V | D | S | V | V | I | D | R | K | I | N | P |
Query Conservation |   |
  |
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . |
|
Template Conservation |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   | . | . | . | . | . | . |   |   |   |
|   |   | . | . | . | . |
|
Template Sequence |   |
C | R | A | S | L | K | K | L | I | D | Y | H | V | A | S | G | T | S | A | I | V | S | V | G | T | T | G | E | S | A | T | L | N | H | D | E | H | A | D | V | V | M | M | T | L | D | L | A | D | G | R | I | P | V | I | A | G | T | G | A | N | A | T | . |
. |
. |
. |
. |
. |
A | E | A | I | S | L | . |
. |
. |
. |
T |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | S | S | T | T | T | T | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
|  |  |  |  |
|
|
| S | S |  | . | . | . | . | . | . |  |  |  |  |  |  | . | . | . | . |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . |  |  |  |  |  |  | . | . | . | . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | |
|
|
|
. |
  |
  |   |
113 | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | Q | I | K | Q | D | G | G | K | A | L | K | L | L | V | L | W | R | S | D | E | D | A | Q | Q | R | L | D | M | V | K | E | F | N | E | L | C | H | S | H | G | L | V | S | I | I | E | P | V | V | R | P | P | R | R | G | D | K | F | D | R | E | Q | A | I | I | D | A | A | K | E | L | G | D | S | G | A | D | L | Y |
Query Conservation |   |
|   |
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|   |   |   |
|
|
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   | . | . | . |   |   |
|
|   |
| . | . |
|
|   |
|   |   |
|
|   |   |   |
| . |   |   |   |
|   |   |
|   |   |   | . | . | . |
|   |
|   |
|
|
Template Sequence |   |
Q | R | F | N | D | S | G | I | V | G | C | L | T | V | T | P | Y | Y | N | R | P | S | Q | E | G | L | Y | Q | H | F | K | A | I | A | E | H | T | . |
. |
. |
D | L | P | Q | I | L | . |
. |
Y | N | V | P | S | A | T | G | C | D | L | L | . |
P | E | T | V | G | R | L | A | K | V | . |
. |
. |
K | N | I | I | G | I |
Template Known Secondary structure |   |
 | T | T | T | T | S | S |
|
|  |  |  |  |  |
|
|
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| . | . | . | S | S |
|  |  |  | . | . |  |  |
|  |  |  |  | S |
|
|
|
| . |  |  |  |  |  |  |  |  | T | S | . | . | . | T | T |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|  |  |  | . | . |  |  |
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
|
|
. | . | . | 130 | . | . | |
|
. | . | . | . | . | . | . | 140 | . | . | . | . | |
. | . | . | . | . | 150 | . | . | . | . | |
|
|
. | . | . | . | . | 160 |
  |
  |   |
193 | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | V | E | M | P | L | Y | G | K | G | P | Q | Q | E | L | L | C | A | S | Q | R | L | N | D | H | I | N | M | P | W | V | I | L | S | S | G | V | D | E | K | L | F | P | R | A | V | R | V | A | M | T | A | G | A | S | G | F | L | A | G | R | A | V | W | A | S | V | V | G | L | P | D | N | E | L | M | L | R | D | V |
Query Conservation |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |
|
|
|   |
|
|   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |
| . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
| . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|
Template Sequence |   |
K | E | A | T | G | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
L | T | R | V | N | Q | I | K | E | L | V | S | D | D | F | V | L | L | S | G | D | D | . |
. |
. |
. |
. |
. |
A | S | A | L | D | F | M | Q | L | G | G | H | G | V | I | S | V | T | A | N | V | A | A | R | D | M | A | Q | M | C | K | L | A | A | E | G | H |
Template Known Secondary structure |   |
 |  |
| S |
|
| . | . | . | . | . | . | . | . | . | T | T |  |  |  |  |  |  | T | T | S |
| T | T | S |  |  |  |  |
|
| G | . | . | . | . | . | . | G | G |  |  |  |  |  |  | T | T |
|
|  |  |  |  | S | G | G | G | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . |
  |
  |   |
273 | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
C | A | P | K | L | Q | Q | L | G | D | I | V | D | E | M | M | A | K | R | R |
Query Conservation |   |
  |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
F | A | E | A | R | V | I | N | Q | R | L | M | P | L | H | N | K | L | F |
Template Known Secondary structure |   |
. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
  |