|   |
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | |
|
|
270 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
T | L | Q | P | I | L | E | K | L | Y | Q | A | Q | T | L | S | Q | Q | E | S | H | Q | L | F | S | A | V | V | R | G | E | L | K | P | E | Q | L | A | A | A | L | V | S | M | K | I | R | G | E | H | P | N | E | I | A | G | A | A | T | A | L | L | E | N | A | A | P | F | P | R | P | . |
. |
. |
D | Y | L | F | A | D |
Query Conservation |   |
  |   |   |   |   |
|   |
|   |   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|   |
|
|
|
|   |
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|   |
|
|   |   |
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|
|
|
|
|
|   |
|
|   |   |
|
|   |
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
Template Sequence |   |
Q | L | P | E | L | I | R | M | K | R | D | G | G | R | L | S | E | A | D | I | R | G | F | V | A | A | V | V | N | G | S | A | Q | G | A | Q | I | G | A | M | L | M | A | I | R | L | R | G | M | D | L | E | E | T | S | V | L | T | Q | A | L | A | Q | S | G | Q | Q | L | E | W | P | E | A | W | R | Q | Q | L | V | D |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
|
|
|
| G | G | G | T | T | T | B |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
35 | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . |
  |
  |   |
276 | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | |
. | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | |
. | 350 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  | . |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
I | V | G | T | G | G | D | G | S | N | S | I | N | I | S | T | A | S | A | F | V | A | A | A | C | G | L | K | V | A | K | H | G | N | R | S | V | S | S | K | S | G | S | S | D | L | L | A | A | F | . |
G | I | N | L | D | M | N | A | D | K | S | R | Q | A | L | D | E | L | G | V | C | F | L | . |
F | A | P | K | Y |
Query Conservation |   |
  |   |
|
|
|
|
|
|   |   |
|   |
|
|
|   |   |   |
|   |
|
|
|
|   |
|
|   |
|   |
|
|
|   |
|   |   |
|
|   |   |
|
|
|
|   |
|
|   |
| . |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   | . |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|
|
|   |
|
| . | . | . |
|
|   |   |
|   |
|   |
|
|   |
|
|   |
|   |
|
|
|   |
|
|
|
|
|   |   |
|
|
|
|   |
|
|
|
|   |
|
|   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
K | H | S | T | G | G | V | G | D | K | V | . |
. |
. |
S | L | V | L | A | P | A | L | A | A | C | G | C | K | V | P | M | I | S | G | R | G | L | G | H | T | G | G | T | L | D | K | L | E | S | I | P | G | F | N | V | I | Q | S | P | E | Q | M | Q | V | L | L | D | Q | A | G | C | C | I | V | G | Q | S | E | Q | L |
Template Known Secondary structure |   |
 |  |  | S |
|
| T | T |
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T |
| B |  |  |  |  |
|
|
|
| B | T | T | B |
|
|  |  |  |  |  | T | T | S | T | T |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | S |  |  |  |  |
|
|
| S | S | S |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
115 | . | . | . | . | 120 | . | . | . | . | . | |
|
|
. | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . |
  |
  |   |
354 | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | |
. | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | T | G | F | R | H | A | M | P | V | R | Q | Q | L | K | T | R | T | L | F | N | V | L | G | P | L | I | N | P | A | H | P | P | L | A | L | I | G | V | Y | S | P | E | L | V | L | P | I | A | E | T | L | R | V | L | G | Y | Q | R | A | A | V | V | H | S | . |
G | G | M | D | E | V | S | L | H | A | P | T | I | V |
Query Conservation |   |
  |
|
|   |   |   |
|   |   |
|
|   |   |
|
|   |
|
|   |   |
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   | . |   |
|   |
|
|   |
|   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
| . | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|   |
|   |   |
|
|   |   |
|
| . | . |
|
|   |   |
| . | . |
|
|
|   |   |
| . | . | . | . | . | . | . | . |
|   |
|
|
|   |
|   |
|   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |
|   |   |   |
|   |
|   |
|
|
| . | . |   |   |   |   |   |
Template Sequence |   |
V | P | A | D | G | I | L | Y | A | A | R | D | V | T | A | . |
. |
T | V | D | S | L | . |
. |
P | L | I | T | A | S | . |
. |
. |
. |
. |
. |
. |
. |
I | L | S | K | K | L | V | E | G | L | S | A | L | V | V | D | V | K | F | G | A | G | A | V | F | P | N | Q | E | Q | A | R | E | L | A | . |
. |
K | T | L | V | G |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  | T | T | T | . | . |
| S | S |
|  | . | . |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  |  |  | S | T | T | S | S | S |
| S |  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|  | . | . |  |  |
|
|  |  | . | . | . | . | . | . | . | . |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  | . | . |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
192 | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
|
. | . | . | 210 | . | |
|
. | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
|
. | . | . | . | . |
  |
  |   |
433 | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | |
. | . | . | . | . | . | . | . | . | 510 | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | E | L | H | D | G | E | I | K | S | Y | Q | L | T | A | E | D | F | G | L | T | P | Y | H | Q | E | Q | L | A | G | G | T | P | E | E | N | R | D | I | L | T | R | L | L | Q | G | K | G | D | A | A | H | E | A | A | V | A | A | N | V | A | M | L | M | R | L | H | G | . |
H | E | D | L | Q | A | N | A | Q | T | V |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|   |   |   |
| . |   |   |   |   |   |
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|
| . | . | . | . | . | . | . |   |   |
|
|   |
|   |
|   |   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|   |   |
|   |   |   |
|   |
|   |
|   |   |
|
|   |   |   |
|
Template Sequence |   |
V | G | A | S | L | G | L | R | V | A | A | A | L | T | A | M | D | K | P | L | G | . |
. |
. |
. |
. |
. |
. |
R | C | V | G | H | A | L | E | V | E | E | A | L | L | C | M | D | G | A | G | P | P | D | L | R | D | L | V | T | T | L | G | G | A | L | L | W | L | S | G | H | A | G | T | Q | A | Q | G | A | A | R | V |
Template Known Secondary structure |   |
 |  |  |  | T | T |
|
|  |  |  |  |  |  |  |
| S | S |
| S | S | . | . | . | . | . | . | . | S |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S | S |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
258 | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 |
  |
  |   |
512 | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | |
. | . | . | 530 | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |  | . |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
L | E | V | L | R | S | G | S | A | Y | D | R | V | T | A | . |
L | A | A | R | G |
Query Conservation |   |
  |   |   |
|   |
|
|   |
|   |   |
|
|   |   | . |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|
|
|
|   |   |
|
|   |   |   |
|   |
|
|
|
Template Sequence |   |
A | A | A | L | D | D | G | S | A | L | G | R | F | E | R | M | L | A | A | Q | G |
Template Known Secondary structure |   |
 |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
331 | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . |
  |