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Job DescriptionP00904
Confidence100.00%DateWed Jan 25 15:20:09 GMT 2012
Rank10Aligned Residues309
% Identity24%Templatec2j0fC_
PDB info PDB header:transferaseChain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design
Resolution2.31 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   199200.........210.........220.........230.........240.........250.........260......... 270.....
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Query Sequence  TLQPILEKLYQAQTLSQQESHQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRP. . . DYLFAD
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Template Sequence  QLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVD
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GGGTTTB
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   35....40.........50.........60.........70.........80.........90.........100.........110....
 
   276...280.........290.........300.........310.........320..... ....330.........340........ .350...
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Query Sequence  IVGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAF. GINLDMNADKSRQALDELGVCFL. FAPKY
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Template Sequence  KHSTGGVGDKV. . . SLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQL
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   115....120..... ....130.........140.........150.........160.........170.........180.........190.
 
   354.....360.........370.........380.........390.........400.........410........ .420.........430..
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Query Sequence  HTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHS. GGMDEVSLHAPTIV
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Template Sequence  VPADGILYAARDVTA. . TVDSL. . PLITAS. . . . . . . . ILSKKLVEGLSALVVDVKFGAGAVFPNQEQARELA. . KTLVG
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   192.......200...... ...210. ...... ..220.........230.........240.........250.. .....
 
   433......440.........450.........460.........470.........480.........490.........500 .........510.
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Query Sequence  AELHDGEIKSYQLTAEDFGLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHG. HEDLQANAQTV
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Template Sequence  VGASLGLRVAAALTAMDKPLG. . . . . . . RCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARV
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   258.260.........270........ .280.........290.........300.........310.........320.........330
 
   512.......520...... ...530.
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Query Sequence  LEVLRSGSAYDRVTA. LAARG
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Template Sequence  AAALDDGSALGRFERMLAAQG
Template Known Secondary structure  SSTT
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   331........340.........350.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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