|   |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
. | . | . | |
|
|
|
|
130 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|  | . | . | . | . | . |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| . |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
G | A | Y | S | L | V | D | H | G | I | K | A | M | N | G | A | L | R | D | K | K | Y | G | G | W | Y | A | C | V | N | D | E | G | V | V | D | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | K | Q | G | Y | Q | H | F | F | A | L | L | G | A | A | S | A | V | T | T | . |
G | H | P | . |
. |
. |
. |
. |
E | A | R |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |
|
|   |
|   |
|
|
|   |   |   |   |
| . |   |   |   | . | . | . | . | . |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|
|   |   |   |   |   |
Template Sequence |   |
H | F | I | E | R | L | A | A | N | G | K | K | T | A | E | I | N | Y | G | A | R | G | W | V | A | H | H | N | A | D | L | W | G | Q | T | A | P | V | G | D | F | G | H | G | D | P | V | W | A | F | W | P | X | G | G | V | W | L | T | Q | H | L | W | E | H | Y | T | F | G | E | D | E | A | Y | L | R | D | T | A | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S |
|
|
|
| S |  |  |
| T | T |
|
|
| S |
|
| B | T | T | T | T | S |
|  |  |  |  |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  | T |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
396 | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . |
  |
  |   |
133 | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
170 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | |
190 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Query Sequence |   |
K | L | L | D | Y | T | I | E | I | I | E | K | Y | F | W | S | E | E | E | Q | M | C | L | E | S | W | D | E | A | F | S | K | T | E | E | Y | R | . |
. |
. |
. |
. |
. |
. |
. |
G | G | N | A | N | M | . |
. |
. |
. |
. |
. |
H | A | V | E | A | F | L | I | V | Y | D | V | T | H | . |
D | K | K | W | L | D | R | A |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . |   |   |
|   |   |
| . | . | . | . | . | . |
|
|
|
|
|   |
|
|   |   |   |
|
|   | . |
|   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |   | . | . |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|
Template Sequence |   |
P | I | X | K | E | A | A | L | F | C | L | D | W | L | I | E | N | E | A | G | Y | L | V | . |
. |
T | S | P | S | T | S | P | E | Q | R | F | R | I | G | E | K | G | Y | A | V | S | S | A | T | T | X | D | L | S | L | I | A | E | C | F | D | N | C | I | Q | A | A | K | R | L | S | I | D | E | D | F | V | K | A | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
| T | T | S |
|  |  | . | . |
| S | S | B |
| B | T | T | B |
|  |  |  | T | T |  |  |  |
|
| B | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|
|
|
|  |  |  | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
476 | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | |
|
. | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . |
  |
  |   |
198 | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | R | V | A | S | V | I | I | H | D | V | A | R | N | N | H | Y | R | V | N | E | H | F | D | T | Q | W | N | P | L | P | D | Y | N | K | D | N | P | A | H | R | F | R | A | F | G | G | T | P | G | H | W | I | E | W | G | R | L | M | L | H | I | H | A | A | L | E | A | R | C | E | Q | P | P | A | W | L | L | E | D |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
| . | . | . | . | . | . |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |
|   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|
Template Sequence |   |
S | D | A | K | Q | R | L | L | P | L | Q | I | G | K | R | G | Q | L | . |
. |
. |
. |
. |
. |
Q | E | W | S | N | D | F | E | D | E | D | V | H | H | R | H | V | S | H | L | V | G | I | Y | P | G | R | L | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | E | Q | S | A | P | N | L | F | E | A |
Template Known Secondary structure |   |
 |  |  |  |  |  | B |
|
|
|
| B |
| T | T | S | S | B | . | . | . | . | . | . |
| S | S | S | S |
|
|  |  | S |
| T | T |
| S |
|
| G | G | G | T | T | T | T | T |
|
| S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T | T |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
554 | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 610 | . |
  |
  |   |
278 | . | 280 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
Query Sequence |   |
A | K | G | L | F | N | A |
Query Conservation |   |
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |
Template Sequence |   |
A | K | T | S | L | E | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
  |   |
612 | . | . | . | . | . | . |
  |