|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
|
|
|
|
|
Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|
|  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
Query Sequence |   |
K | K | I | P | L | G | T | T | D | I | T | L | S | R | M | G | L | G | T | W | A | I | G | G | G | P | A | W | N | G | D | L | D | R | Q | I | C | I | D | T | I | L | E | A | H | R | C | G | I | N | L | I | D | T | A | P | G | Y | N | F | G | N | S | E | V | I | V | G | Q | A | L | K | K | L | . |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |
|   |
|
|   |
|
|   |   |
|
|   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|
|
|
|   |   |
|
|   |
|   |
|
|   |   |
|
|   |
|
|   |   |   | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |
| . |   |
|
|   |   |
|   |   |
|
|   |
|
|   |   |   |
|   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|
|
|
|   |   |
|
| . | . | . |
|
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | C | V | K | L | . |
N | D | G | H | F | M | P | V | L | G | F | G | T | Y | A | P | P | E | . |
. |
. |
. |
. |
. |
. |
V | P | R | S | K | A | L | E | V | T | K | L | A | I | E | A | G | F | R | H | I | D | S | A | H | L | Y | N | . |
. |
. |
N | E | E | Q | V | G | L | A | I | R | S | K | I | A | D | G | S | V |
Template Known Secondary structure |   |
|  |  |  |
| . | T | T | S |
|  |  |  | S |  |  |  |  |
|
|
|
| T | T | . | . | . | . | . | . | . | S |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
|
| G | G | G | T | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
Template Predicted Secondary structure |   |
|  |  |  |
| . |
|
|
|
|  |  |
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
6 | . | . | . | 10 | |
. | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
. | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . |
  |
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
P | R | E | Q | V | V | V | E | T | K | C | G | I | V | W | E | R | K | G | S | L | F | N | K | V | G | D | R | Q | L | Y | K | N | L | S | P | E | S | I | R | E | E | V | A | A | S | L | Q | R | L | G | I | D | Y | I | D | I | Y | M | T | H | W | Q | S | V | P | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|
|
|   |   |
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|   |   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|   |   |
|   |
|
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | R | E | D | I | F | Y | T | S | K | L | W | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | F | H | R | P | E | L | V | R | P | A | L | E | N | S | L | K | K | A | Q | L | D | Y | V | D | L | Y | L | I | H | S | P | M | S | L | K | P | G | E | E | L | S | P | T | D | E | N | G | K |
Template Known Secondary structure |   |
| G | G | G |
|  |  |  |  |  |  |
| G | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G | G |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
|  |  |  |  |  |  |
|
| S |
|
| B |
|
| S | S |
| S | S |
| B |
| T | T | S |
|
Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . |
  |
  |   |
|
|
|
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
. | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
F | F | T | P | I | A | E | T | V | A | V | L | N | E | L | K | S | E | G | K | I | R | A | I | G | A | A | N | V | D | A | D | H | I | R | E | Y | L | Q | Y | G | . |
. |
E | L | D | I | I | Q | A | K | Y | S | I | L | D | R | A | M | E | N | E | L | L | P | L | C | R | D | N | G | I | V | V | Q | V | Y |
Query Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|
|   |
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
Template Sequence |   |
V | I | F | D | I | V | D | L | C | T | T | W | E | A | M | E | K | C | K | D | A | G | L | A | K | S | I | G | V | S | N | F | N | R | R | Q | L | E | M | I | L | N | K | P | G | L | K | Y | K | P | V | C | N | Q | V | E | C | H | P | Y | F | N | R | S | K | L | L | D | F | C | K | S | K | D | I | V | L | V | A | Y |
Template Known Secondary structure |   |
B |
| B |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  | T |
| T | T |
|
|
|
|
| S |  |  |  |  |  |
| B | T | T | B |
|
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
137 | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
  |
  |   |
218 | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | P | L | E | Q | G | L | L | T | G | T | I | T | R | D | Y | V | P | G | G | A | R | A | N | K | V | W | F | Q | R | E | N | M | L | K | V | I | D | M | L | E | Q | W | Q | P | L | C | A | R | Y | Q | C | T | I | P | T | L | A | L | A | W | I | L | K | Q | S | D | L | I | S | I | L | S | G | A | T | A | P | E | Q |
Query Conservation |   |
  |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|
|   |   |   |   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |
| . | . |
|
|   |
|   |   |   |   |
|   |
Template Sequence |   |
S | A | L | G | S | Q | R | D | K | R | W | V | D | P | N | S | P | V | L | L | E | D | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | L | C | A | L | A | K | K | H | K | R | T | P | A | L | I | A | L | R | Y | Q | L | Q | R | G | V | V | . |
. |
V | L | A | K | S | Y | N | E | Q | R |
Template Known Secondary structure |   |
S | T | T | S |
|
|
|
| T | T | T | S |
| T | T | S |
|
| G | G | G |
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|  | . | . |  |  |  |  |
|
| S |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
|
. | . | . | 270 | . | . | . | . | . | . |
  |
  |   |
298 | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | R | E | N | V | A | A | L | N | I | N | L | S | D | A | D | A | T | L | M | R | E | M | A | E | A | L | E | R |
Query Conservation |   |
|   |
|
|
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|   |
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|   |
|   |   |   |   |
|   |
Template Sequence |   |
I | R | Q | N | V | Q | V | F | E | F | Q | L | T | A | E | D | M | K | A | I | D | G | L | D | R | N | L | H | Y |
Template Known Secondary structure |   |
 |  |  |  | G | G | G | G | G |
|
|
|
|  |  |  |  |  |  |  |  | T | T |
|
|
|
|
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
277 | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . |
  |