|   |
26 | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | |
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
G | P | A | W | N | G | D | L | D | R | Q | I | C | I | D | T | I | L | E | A | H | R | C | G | I | N | L | I | D | T | A | P | G | Y | N | F | G | N | S | . |
. |
. |
. |
. |
. |
E | V | I | V | G | Q | A | L | K | K | L | P | R | E | Q | V | V | V | E | T | K | C | G | I | V | W | E | R | . |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|
|
|
|   |   |
|
|   |
|   |
| . | . | . | . | . | . |
|   |   |
|
|   |
|
|   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |   |   |   |   |   | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|   |   |   |
|   |
|
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
Template Sequence |   |
P | M | L | K | D | G | G | V | D | W | K | S | L | E | K | L | V | E | W | H | I | E | Q | G | T | N | S | I | V | A | V | G | T | T | G | E | A | S | T | L | S | M | E | E | H | T | Q | V | I | K | E | I | I | R | V | A | N | K | R | I | P | I | I | A | G | T | G | A | N | S | T | R | E | A | I | E | L | T | K | A |
Template Known Secondary structure |   |
| B |
| T | T | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | S | S | G | G | G | T | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
12 | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . |
  |
  |   |
|
|
93 | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 |
Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
K | G | S | L | F | N | K | V | G | D | R | Q | L | Y | K | N | L | S | P | E | S | I | R | E | E | V | A | A | S | L | Q | R | L | G | I | D | Y | I | D | I | Y | M | T | H | W | Q | S | V | P | P | F | F | T | P | I | A | E | T | V | A | V | L | N | E | L | K | S | E | G | K | I | R | A | I | G | A | A | N |
Query Conservation |   |
. | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|
|   |
|
|
|
|   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   | . | . | . |   |
|
|   |   |
|
|   |
|   |   |
|
|   |   |   |   |   |   |   | . | . | . | . |
|   |   |
|   |   |   |
|   |
|   |
|
|
|   |
|   |
Template Sequence |   |
A | K | D | L | G | A | D | A | A | L | L | V | T | P | Y | Y | N | K | P | T | Q | E | G | L | Y | Q | H | Y | K | A | I | A | E | A | V | E | . |
. |
. |
L | P | L | I | L | Y | N | V | P | G | R | T | G | V | D | L | S | N | D | T | . |
. |
. |
. |
A | V | R | L | A | E | I | P | N | I | V | G | I | K | D | A | T |
Template Known Secondary structure |   |
 |  |  | T | T |
| S |  |  |  |  |  |
|
|
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | S |
|  |  |  |  |  |
|  |  |  |  | S |
|
|
|
|  |  |  | . | . | . | . |  |  |  |  | T | T | S | T | T |  |  |  |  |  |  |
| S |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
|
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | |
|
|
|
. | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
  |
  |   |
171 | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | D | A | D | H | I | R | E | Y | L | Q | Y | G | E | L | D | I | I | Q | A | K | Y | S | I | L | D | R | A | M | E | N | E | L | L | P | L | C | R | D | N | G | I | V | V | Q | V | Y | S | P | L | E | Q | G | L | L | T | G | T | I | T | R | D | Y | V | P | G | G | A | R | A | N | K | V | W | F | Q | R | E | N | M |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . |
|   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
Template Sequence |   |
G | D | V | P | R | G | K | A | L | I | D | A | L | N | G | K | M | A | V | Y | S | . |
. |
. |
. |
. |
. |
. |
G | D | D | E | T | A | W | E | L | M | L | L | G | A | D | G | N | I | S | V | T | A | N | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | P | K | A | M | S | E | V | C | A | V | A | I | A | K | D | E |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  | S | S | T | T | S |  |  |  |  | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  | S | G | G | G | T | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
  |
  |   |
251 | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | V | I | D | M | L | E | Q | W | Q | P | L | C | A | R | Y | Q | C | T | I | P | T | L | A | L | A | W | I | L | K | Q | S | D | L | I | S | I | L | S | G | A | T | A | P | E | Q | V | R | E | N | V | A | A | L | N | I | N | L | S | D | A | D | A | T | L | M | R | E | M | A | E | A | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   | . | . |   |   |
|   |   |
|   |
| . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
Q | Q | A | K | T | L | N | N | K | I | A | N | L | H | N | I | L | F | C | E | S | N | P | I | P | V | K | W | A | L | H | E | M | G | L | . |
. |
I | D | T | G | I | R | L | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | T | P | L | A | E | Q | Y | R | E | P | L | R | N | A | L | K | D | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  | T | T | S | S | S | T | T |  |  |  |  |  |  |  |  | T | T | T | S | . | . | S |
| B |
|
|
| T | T | . | . | . | . | . | . | . | . | . | . | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
227 | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
|
. | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . |
  |