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Job DescriptionP33937
Confidence100.00%DateThu Jan 5 11:52:56 GMT 2012
Rank20Aligned Residues711
% Identity17%Templated1y5ia2
SCOP infoFormate dehydrogenase/DMSO reductase, domains 1-3 Formate dehydrogenase/DMSO reductase, domains 1-3 Formate dehydrogenase/DMSO reductase, domains 1-3
Resolution1.90

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   37..40...... ...50.........60.........70........ .80.........90.........100...
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Query Sequence  EAIKWDKAPC. RFCGTGCGVLVGTQQGRVVACQGDPDAPVNRG. . . . . . . LNCIKGYFLPKIMYGKDRLTQPLLR. . . . .
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Template Conservation    
         

   
   
 



 
 
     
 
    
 
    
 
 

 
    

 







 
     
Template Sequence  QHDKIVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMK
Template Known Secondary structure 

S


SSSS



TT


S



TTS


TT


TGGGGGTSTTB

S
Template Predicted Secondary structure 


















































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   40.........50.........60.........70.........80.........90.........100.........110.........
 
   104.....110.........120.........130.........140.........150....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . MKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIW
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Template Sequence  MWREAKALHSDPVEAWASIIEDADKAKSFKQ. . . ARGRGGFVRSSWQEVNELIAASNVYTIKNYGPDRVAGFSPIPAMSM
Template Known Secondary structure  TT
SST
T...TTTSS


T
GGG


GGGS
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   120.........130.........140.........150 .........160.........170.........180.........190......
 
   155....160.........170.........180.........190.........200.........210.........220.........230....
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Query Sequence  EGYAASKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAEMHPILWSRITNRRLSN
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Template Sequence  VSYASGARYLSLIGGTCLSFYDWYCDLPP. . ASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVR. . Y
Template Known Secondary structure  T


TTTTT
S
T..S
S




TT
SS

SGGGG..G
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   197..200.........210.........220..... ....230.........240.........250.........260.........270. .
 
   235....240.........250.........260.........270.........280... ......290.........
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Query Sequence  QNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYIIQNNAINQ. . . . . . DFFSKHVNLRKGATDI. . . . . . . . .
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Template Sequence  KGTKTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRYTDMPMLVMLEERDGYYAAG
Template Known Secondary structure  GT

SS

TSS


TT
TTTS

BSTTB
SSS
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   273......280.........290.........300.........310.........320.........330.........340.........350..
 
  
Predicted Secondary structure  ................................................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation    

 

               

 
  
    
 
  
        
                                
Template Sequence  RMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIGFRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFP
Template Known Secondary structure 
BGGGBTTGGG

SSGGG
B
BTTS

BTTSGGGTSSS
S

S
SSBBTTT

B

B



TTS
S
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   353......360.........370.........380.........390.........400.........410.........420.........430..
 
   300.........310.........320.........330.. .......340......
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Query Sequence  . . . . . . . . . . . . . . . GYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAF. . . . . . . . . . . . . . . . . . VAEYTLEKTAEMTG
Query Conservation  ...............                          
  
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Template Sequence  YFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWAEQITG
Template Known Secondary structure 

TT


TTS





SBTTS
TTB

SS

TTSBSSTTS

TT

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   433......440.........450.........460.........470.........480.........490.........500.........510..
 
   347..350.........360. ........370.........380.........390.........400.........410.....
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Query Sequence  VPKDQLEQLAQLYAD. . . . PNKKVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQPGCGPFSLTGQPSACG. . . . . . .
Query Conservation 

   
  

   
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Template Sequence  VSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQPL
Template Known Secondary structure 

TS

TSTTTT
TTSTT

SS



SS
Template Predicted Secondary structure 









































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   513......520.........530.........540.........550.........560.........570.........580.........590..
 
   416...420.........430.........440.........450.........460....
Predicted Secondary structure  ...............................






























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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPSGTIPAKIGLHAVAQ
Query Conservation  ...............................            
                                    
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Template Conservation    
 
         
                       
                     

 
  
             
Template Sequence  AFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEA
Template Known Secondary structure  TTTT
S


TTGGGG



SGGGS
TTS
GGGS
S
TTSS

SS
BSS
TTS
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   593......600.........610.........620.........630.........640.........650.........660.........670..
 
   465.. ..470.........480.........
Predicted Secondary structure 
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Query Sequence  DRA. . . . . . . . . . . . . . . . . . . . . . . . . LKDGKLNVYWTMCTNNMQAGPN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Conservation                                    
  

   
 
 
   
  
 

       
               
Template Sequence  EKAGMNPVDYTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQGKDLGQQGGVKPE
Template Known Secondary structure  TTS
TSS
BGGG
TTSSSSS

S

TTTTT
SSTT
S




S

TTTTT



S
Template Predicted Secondary structure 






































































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   673......680.........690.........700.........710.........720.........730.........740.........750..
 
   490.........500.........510.........520.........530... ......540.........550.........560........
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Query Sequence  INEERMPGWRDPRNFIIVSDPYPTVSALAADLILPTAMWVEKEG. AYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFSRR
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Template Sequence  EVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKK
Template Known Secondary structure  SS


SS





SSB

T
SB

TTSS


SSSS

SS

STT
B
Template Predicted Secondary structure 































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   753......760.........770.........780.........790.........800.........810.........820.........830..
 
   569570.........580.........590.........600.........610........ .620..
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Query Sequence  FKTEEVWPEDLLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDES. . . . . . . . . . . . . . . . . . . . . . . . . . RELG
Query Conservation 

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Template Sequence  FS. . EVCVGHLGKETDIVTLPIQHDSAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIG
Template Known Secondary structure  ..TTTT




TTSGGG


SSS


GGGTSS


BTTTB
GGGTB

TT
Template Predicted Secondary structure  ..












































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   833. .....840.........850.........860.........870.........880.........890.........900.........910
 
   623......630.........640.........650.........660.........670.... .....680
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Query Sequence  FYLQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGN. . . . . . . . . . . . . . . . . . . . . . DPYVKA
Query Conservation                                                      ......................      
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Template Conservation                  
                            
                      
     
     
Template Sequence  NGGKGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAWAALSEFTGRDHTHLALNKE
Template Known Secondary structure  TT


B

SSTTTTSBB

S
TTTBSS

GGGTGGGT
Template Predicted Secondary structure 
















































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   911........920.........930.........940.........950.........960.........970.........980.........990
 
   681........690.........700.........710.........720.........730.... .....740.........750.....
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Query Sequence  GEGYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRV. . . . . PELHRAFPEAVLFIHPLDAKA
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Template Conservation                     
           
           

 
 

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Template Sequence  DEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHELIPWRTLSG. RQQLYQDHQWMRDFGESLLVYRPPIDTRS
Template Known Secondary structure  T
B

S




TTSSS


SSS


TT



SSTTS.SB




STT
SS










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   991........1000.........1010.........1020.........1030.........1040 .........1050.........1060.........
 
   756.
Predicted Secondary structure 
Query SS confidence 

Query Sequence  RD
Query Conservation 

Alig confidence 

Template Conservation    
Template Sequence  VK
Template Known Secondary structure  ST
Template Predicted Secondary structure 
Template SS confidence 

   1070.
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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