|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | I | T | L | P | D | G | S | Q | R | H | Y | D | H | A | V | S | P | M | D | V | A | L | D | I | G | P | G | L | A | K | A | C | I | A | G | R | V | N | G | E | L | V | D | A | C | D | L | I | E | N | D | A | Q | L | S | I | I | T | A | K | D | E | E | G | L | E | I | I | R | H | S | C | A | H | L | L | G | H |
Query Conservation |   |
  |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |
|
|   |   |   |
|   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |
|
|   |   |   |
|   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|
|   |   |
Template Sequence |   |
I | N | I | Q | F | P | D | G | N | K | K | A | F | D | K | G | T | T | T | E | D | I | A | Q | S | I | S | P | G | L | R | K | K | A | V | A | G | K | F | N | G | Q | L | V | D | L | T | K | P | L | E | T | D | G | S | I | E | I | V | T | P | G | S | E | E | A | L | E | V | L | R | H | S | T | A | H | L | M | A | H |
Template Known Secondary structure |   |
|
|  |  |
| S | S | S |
|  |  |
|
|
| S | S | B |
|  |  |  |  |  |  |  |  |
|  |  |  |  | T | T |
|
|  |  |  |  | T | S | S |  |  |  | S | S |
|
| B |
| S |
|
| B |  |  |  |  |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
  |
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | I | K | Q | L | W | P | H | T | K | M | A | I | G | P | V | I | D | N | G | F | Y | Y | D | V | D | L | D | R | T | L | T | Q | E | D | V | E | A | L | E | K | R | M | H | E | L | A | E | K | N | Y | D | V | I | K | K | K | V | S | W | H | E | A | R | E | T | F | A | N | R | G | E | S | Y | K | V | S | I | L | D |
Query Conservation |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |
|
|   |   |   |   |
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |
|   |
|
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |
|
|   |
|   |   |
|
|   |
|
|
|   |   |   |
| . | . |   |   |   |   |   |
|   |   |
|
|   |
Template Sequence |   |
A | I | K | R | L | Y | G | N | V | K | F | G | V | G | P | V | I | E | G | G | F | Y | Y | D | F | D | I | D | Q | N | I | S | S | D | D | F | E | Q | I | E | K | T | M | K | Q | I | V | N | E | N | M | K | I | E | R | K | V | V | S | R | D | E | A | K | E | L | F | . |
. |
S | N | D | E | Y | K | L | E | L | I | D |
Template Known Secondary structure |   |
 |  |  |  |  |
| S | S |
|
|
|
|
|
|
|  |  | T | T |  |  |  |
|
|
|
|
| S | S |
|
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |
| . | . |
| S |
|  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | |
|
. | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | N | I | A | H | D | D | K | P | G | L | Y | F | H | E | E | Y | V | D | M | C | R | G | P | H | V | P | N | M | R | F | C | H | H | F | K | L | M | K | T | A | G | A | Y | W | R | G | D | S | N | N | K | M | L | Q | R | I | Y | G | T | A | W | A | D | K | K | A | L | N | A | Y | L | Q | R | L | E | E | A | A | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |
|
|
|   |
|
|
|
|   |   |
|
|   |
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |
|   |
|   |
|
|
|
|   |   |
|
|   |
|   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
. |
A | I | P | E | D | E | N | V | T | L | Y | S | Q | G | D | F | T | D | L | C | R | G | V | H | V | P | S | T | A | K | I | K | E | F | K | L | L | S | T | A | G | A | Y | W | R | G | D | S | N | N | K | M | L | Q | R | I | Y | G | T | A | F | F | D | K | K | E | L | K | A | H | L | Q | M | L | E | E | R | K | E |
Template Known Secondary structure |   |
. |
|
| S | S | S |
|
|
|
|  |  |  |  | T | T |  |  |  |
|
|
| S |
|
|
| S |
| G | G | G |
|
|  |  |  |  |  |  |  |
|
| B |
| S | T | T |
| T | T | S |
|
| B |
|
|  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
  |
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
| . |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | D | H | R | K | I | G | K | Q | L | D | L | Y | H | M | Q | E | E | . |
A | P | G | M | V | F | W | H | N | D | G | W | T | I | F | R | E | L | E | V | F | V | R | S | K | L | K | E | Y | Q | Y | Q | E | V | K | G | P | F | M | M | D | R | V | L | W | E | K | T | G | H | W | D | N | Y | K | D | A | M | F | T | T |
Query Conservation |   |
|
|
|
|   |   |
|   |   |   |   |
|
|   |   |   |   |   | . |   |
|
|   |   |   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|
|   |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |   |
Template Sequence |   |
R | D | H | R | K | I | G | K | E | L | E | L | F | T | N | S | Q | L | V | G | A | G | L | P | L | W | L | P | N | G | A | T | I | R | R | E | I | E | R | Y | I | V | D | K | E | V | S | M | G | Y | D | H | V | Y | T | P | V | L | A | N | V | D | L | Y | K | T | S | G | H | W | D | H | Y | Q | E | D | M | F | P | P |
Template Known Secondary structure |   |
 |
|  |  |  |  |  |  |  | T | T |
|  |  |
|
| T | T | T |
| T | T |
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
|
|
| S |  |  |  | T |  |  |  |  |  |  | T | S | T | T | T | T | T | T | T | S |
|
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
  |
  |   |
321 | . | . | . | |
|
. | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
| . | . |
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | S | E | N | . |
. |
R | E | Y | C | I | K | P | M | N | C | P | G | H | V | Q | I | F | N | Q | G | L | K | S | Y | R | D | L | P | L | R | M | A | E | F | G | S | C | H | R | N | E | P | S | G | S | L | H | G | L | M | R | V | R | G | F | T | Q | D | D | A | H | I | F | C | T | E | E | Q | I | R | D | E | V | N |
Query Conservation |   |
  |   |   |   | . | . |   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|   |
|   |
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
M | Q | L | D | E | T | E | S | M | V | L | R | P | M | N | C | P | H | H | M | M | I | Y | A | N | K | P | H | S | Y | R | E | L | P | I | R | I | A | E | L | G | T | M | H | R | Y | E | A | S | G | A | V | S | G | L | Q | R | V | R | G | M | T | L | N | D | S | H | I | F | V | R | P | D | Q | I | K | E | E | F | K |
Template Known Secondary structure |   |
B |
| S | T | T | S |
|
|  |  |  |
| S |
| S |  |  |  |  |  |  |  |  |  | T | S |
|
| B | T | T | T |
| S |  |  |  |  |  |  |  |  |  |  |
|
|
|
| T | T | T |
| B | T | T | T | B |
| S |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
321 | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 |
  |
  |   |
399 | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | |
|
|
|
. | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | C | I | R | L | V | Y | D | M | Y | S | T | F | G | F | E | K | I | V | V | K | L | S | T | R | . |
. |
. |
. |
P | E | K | R | I | G | S | D | E | M | W | D | R | A | E | A | D | L | A | V | A | L | E | E | N | N | I | P | F | E | Y | Q | L | G | E | G | A | F | Y | G | P | K | I | E | F | T | L | Y | D | C | L |
Query Conservation |   |
  |   |
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |
|   |
|
|   |   | . | . | . | . |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |
Template Sequence |   |
R | V | V | N | M | I | I | D | V | Y | K | D | F | G | F | E | D | Y | S | F | R | L | S | Y | R | D | P | E | D | K | E | K | Y | F | D | D | D | D | M | W | N | K | A | E | N | M | L | K | E | A | A | D | E | L | G | L | S | Y | E | E | A | I | G | E | A | A | F | Y | G | P | K | L | D | V | Q | V | K | T | A | M |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| B |
|
|  |  |  |
|
| S |
|
|
| S | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|  |  |  | T |
| S | B | T | T | B |
|  |  |  |  |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
401 | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 |
  |
  |   |
475 | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | |
. | 550 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
D | R | A | W | Q | C | G | T | V | Q | L | D | F | S | L | P | S | R | L | S | A | S | Y | V | G | E | D | N | E | R | K | V | P | V | M | I | H | R | A | I | L | G | S | M | E | R | F | I | G | I | L | T | E | E | F | A | G | F | F | P | T | W | L | A | P | V | Q | V | V | I | M | N | I | T | . |
D | S | Q | S | E |
Query Conservation |   |
|
|   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
|
|   |
|
|   |
|   |   |
|   |
|   |   |   |
|   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|
|   | . |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|
|
|   |
|   |   |
|   |
|   |   |   |
|   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|
|   |   |
|   |   |   |   |
Template Sequence |   |
G | K | E | E | T | L | S | T | A | Q | L | D | F | L | L | P | E | R | F | D | L | T | Y | I | G | Q | D | G | E | H | H | R | P | V | V | I | H | R | G | V | V | S | T | M | E | R | F | V | A | F | L | T | E | E | T | K | G | A | F | P | T | W | L | A | P | K | Q | V | Q | I | I | P | V | N | V | D | L | H | Y | D |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  |  |  | S | S |  |  |  |  | T | T |
|
|  |  |
| S | S | S |
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | T |
| S | S |
|  |  |  |  |  | S | S | T | T | T | T |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
481 | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 |
  |
  |   |
554 | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | V | N | E | L | T | Q | K | L | S | N | A | G | I | R | V | K | A | D | L | R | N | E | K | I | G | F | K | I | R | E | H | T | L | R | R | V | P | Y | M | L | V | C | G | D | K | E | V | E | S | G | K | V | A | V | R | T | R | R | G | K | D | L | G | S | M | D | V | N | E | V | I | E | K | L | Q | Q | E | I | R |
Query Conservation |   |
  |
|   |   |
|   |   |   |
|
|   |   |
|
|   |
|   |   |
|   |   |   |   |   |
|   |
|
|
|
|   |
|   |   |   |
|
|
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |   |
|
|   |   |
|
|   |
|   |   |
|   |   |   |   |   |
|   |
|
|
|   |   |
|   |   |   |
|   |
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |
|   |   |
|   |
|   |
|   |
|   |   |
|   |   |   |
|   |
Template Sequence |   |
Y | A | R | Q | L | Q | D | E | L | K | S | Q | G | V | R | V | S | I | D | D | R | N | E | K | M | G | Y | K | I | R | E | A | Q | M | Q | K | I | P | Y | Q | I | V | V | G | D | K | E | V | E | N | N | Q | V | N | V | R | Q | Y | G | S | Q | D | Q | E | T | V | E | K | D | E | F | I | W | N | L | V | D | E | I | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |
|
|
| S | S |
|  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
|  |  |  |  |  |  | T |  |  |  |  |  |  | S | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
561 | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 |
  |
  |   |
634 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
Query Sequence |   |
S | R | S | L | K |
Query Conservation |   |
  |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
Template Sequence |   |
L | K | K | H | R |
Template Known Secondary structure |   |
T | T |
|
|
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
  |   |
641 | . | . | . | . |
  |