|   |
35 | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | L | H | A | A | G | K | G | I | N | V | A | K | V | L | K | D | L | G | . |
I | D | V | T | V | G | G | F | L | G | K | D | N | Q | D | G | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | Q | L | F | S | E | L | G | I | A | N | R | F | Q | V | V | Q | G | R | T | R | I |
Query Conservation |   |
  |   |   |   |
|
|   |   |   |
|
|
|   |   |
|   |   |
|
| . |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|   |   |
|   |   |
Template Sequence |   |
E | L | R | I | G | G | Q | A | G | I | M | A | N | L | L | G | G | V | Y | R | I | P | T | I | V | H | V | P | Q | N | P | K | L | Q | A | E | L | F | V | D | G | P | I | Y | V | P | V | F | E | G | N | K | L | K | L | V | H | P | K | D | A | I | A | E | E | E | E | L | I | H | Y | I | Y | E | F | P | R | G | F | Q |
Template Known Secondary structure |   |
 |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
|
|  |  |  |
|
| S |
|
|
|  |  |  |  | T | T | S |
| S | S | S |  |  |  |  |  |  |
| S | S |
|  |  |  |  |
| G | G | G | S |
|
| S |
|
|
|
|  |  |  |  |  |  |  |
| S | S |
|  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
115 | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . |
  |
  |   |
93 | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | V | K | L | T | E | K | D | G | E | V | T | D | F | N | F | S | G | F | E | V | T | P | A | D | W | E | R | F | V | T | D | S | L | S | W | L | G | Q | F | D | M | V | C | V | S | G | S | L | P | S | G | V | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | A | F | T | D | W | M | T | R | L | R | S | Q | C | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |   |
|   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
V | F | D | V | Q | A | P | R | E | N | R | F | I | A | N | A | D | D | Y | N | A | R | V | Y | M | R | R | E | F | R | E | G | F | E | E | I | T | R | N | V | E | L | A | I | I | S | G | L | Q | V | L | K | E | Y | Y | P | D | G | T | T | Y | K | D | V | L | D | R | V | E | S | H | L | N | I | L | N | R | Y | N | V |
Template Known Secondary structure |   |
 | T | T |  |  |
| S | S |
|  |  |  |  |  |  |
|
| S | S | T | T | T | T |
|
|
|  |  |  |  |  | S |  |  |  |  |  | T | T |
| S |  |  |  |  |
|
| G | G | G |
|
| S | B |
| T | T | S |
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
195 | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . |
  |
  |   |
163 | . | . | . | . | . | . | 170 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | |
. | . | . | . | . | . | 220 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
C | I | I | F | D | S | S | R | . |
. |
. |
. |
. |
. |
E | A | L | V | A | G | L | K | A | A | P | W | L | V | K | P | N | R | R | E | L | E | I | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | G | R | K | L | P | E | M | K | D | V | I | E | A | A | H | A | L | R | . |
E | Q | G | I | A | H | V | V | I | S | L | G |
Query Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . |   |   |   |   |   |   |
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|
|
|
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
Template Sequence |   |
K | S | H | F | E | F | A | Y | T | A | N | R | R | V | R | E | A | L | V | E | L | L | P | K | F | T | S | V | G | L | N | E | V | E | L | A | S | I | M | E | I | I | G | D | E | E | L | A | K | E | V | L | E | G | H | I | F | S | V | I | D | A | M | N | V | L | M | D | E | T | G | I | E | R | I | H | F | H | T | Y |
Template Known Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | G | G | G |
| S |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
275 | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . |
  |
  |   |
226 | . | . | . | 230 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 240 |
Predicted Secondary structure |   |
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
A | E | G | A | L | W | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | A | S | G | E | W | I | A |
Query Conservation |   |
  |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
Template Sequence |   |
G | Y | Y | L | A | L | T | Q | Y | R | G | E | E | V | R | D | A | L | L | F | A | S | L | A | A | A | A | K | A | M | K | G | N | L | E | R | I | E | Q | I | R | D | A | L | S | V | P | T | N | E | R | A | I | V | L | E | E | E | L | E | K | E | F | T | E | F | E | N | G | L | I | D | M | V | D | R | Q | L | A | F |
Template Known Secondary structure |   |
T |  |  |  |  |  |  | S | S |
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
| S | T | T | G | G | G | G | G | G | G | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |  |  | T | T |  |  |  |
| S | S |
|  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
355 | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . |
  |
  |   |
241 | . | . | . | . | |
|
. | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | |
. | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
K | P | P | S | V | . |
. |
D | V | V | S | T | V | G | A | G | D | S | M | V | G | G | . |
L | I | Y | G | L | L |
Query Conservation |   |
  |   |   |   |   | . | . |   |
|
|
|
|
|
|
|
|
|   |
|   |
|
| . |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
|   |   |
|   |   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |   |   |   |
Template Sequence |   |
V | P | T | K | I | V | A | S | P | K | S | T | V | G | I | G | D | T | I | S | S | S | A | F | V | S | E | F | G |
Template Known Secondary structure |   |
 |  |
|
|
|
| S | S |
| S |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
435 | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . |
  |