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Job DescriptionP37661
Confidence99.76%DateThu Jan 5 11:56:34 GMT 2012
Rank21Aligned Residues269
% Identity16%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   218.220.........230.........240.........250.........260.........270......... 280.........290. ...
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Query Sequence  WARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKLAQE. . KNLAAFRGYSCD. TAT
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Template Sequence  YQVVCKGESHWVDDDCEEIKVPECPAGFVRPPLIIFSVDGFRASYMKK. . . GSKVMPNIEKLRSCGTHAPYMRPVYPTKT
Template Known Secondary structure  TS



GGGS





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TT
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T

GGGGGS...
TTTSS
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S
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   133......140.........150.........160.........170.........180 .........190.........200.........
 
   295....300....... ..310.........320.........330.........340.........350.
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Query Sequence  KLSLRCMFVRQGG. . . . . . . . . . . . . . . . . . . . . . . AEDNPQRTLKEQNIFAVLKQLGFSSDLYAMQSEMWFYSNTMADN
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Template Sequence  FPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVS. . . . . . . . . . .
Template Known Secondary structure 
S
S


SSTTTT
SSSSGGG
TTS

S

TTT

B





TT...........
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   210.........220.........230.........240.........250.........260.........270........
 
   352.......360.........370.........380...... ...390......... 400.........410.........420....
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Query Sequence  IAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNP. DGKHLIILHTKGS. . . . . . HFNYTQRYPRSFAQWKPECIGVDSG
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Template Sequence  . . . . . . . . . . . . . . . . . IPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGP. . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  .................S
TTS
TTT

S
TT
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   279280.........290.........300.........310.........320..
 
   425....430.........440.........450.... .....460.........470........
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Query Sequence  CTKAQMINSYDNSVTYVDHFISSVIDQVRD. . . . KKAIVFYAADHGESINEREHLHGT. . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  . . . . . . . . EMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRA
Template Known Secondary structure  ........GGTT
TTT
S




SSSGGGT
S

TT
BS
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   323......330.........340.........350.........360.........370.........380.........390....
 
   479480.........490.......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PRELAPPEQFRVPMMVWMS
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Template Sequence  KYDPKTIIAALTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVARKPFQGDHGFDNKVNSMQTVFVGYGP
Template Known Secondary structure 


TTSS
STT

GGGS
GGG


SSTTS
S
TT
S





S
TT
GGG
B
SS
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   395....400.........410.........420.........430.........440.........450.........460.........470....
 
   498.500.........510.........520.........530.........540. ........550.........
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Query Sequence  DKYLENPANAQAFAQLKKEADMKVPRRHVELYDTIMGCLGYTSP. . DGGINENNNWCHIPQAKE
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Template Sequence  T. . . . . . . . . . . . . . . FKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRP
Template Known Secondary structure  S...............B
SS
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GGGT



S
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   493 ......500.........510.........520.........530.........540.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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